Search Results - "Pearlman, David S"

Pathogenesis, prevalence, diagnosis, and management of exercise-induced bronchoconstriction: a practice parameter by Weiler, John M., MD, MBA, Anderson, Sandra D., PhD, DSc, Randolph, Christopher, MD, Bonini, Sergio, MD, Craig, Timothy J., DO, Pearlman, David S., MD, Rundell, Kenneth W., PhD, FACSM, Silvers, William S., MD, Storms, William W., MD, Bernstein, David I., MD, Blessing-Moore, Joann, MD, Cox, Linda, MD, Khan, David A., MD, Lang, David M., MD, Nicklas, Richard A., MD, Oppenheimer, John, MD, Portnoy, Jay M., MD, Schuller, Diane E., MD, Spector, Sheldon L., MD, Tilles, Stephen A., MD, Wallace, Dana, MD, Henderson, William, MD, Schwartz, Lawrence, MD, PhD, Kaufman, David, MD, Nsouli, Talal, MD, Schieken, Lawrence, MD, Rosario, Nelson, MD

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Comparison of mannitol and methacholine to predict exercise-induced bronchoconstriction and a clinical diagnosis of asthma by Anderson, Sandra D, Charlton, Brett, Weiler, John M, Nichols, Sara, Spector, Sheldon L, Pearlman, David S

“…Asthma can be difficult to diagnose, but bronchial provocation with methacholine, exercise or mannitol is helpful when used to identify bronchial…”
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Efficacy and safety of budesonide/formoterol pMDI vs budesonide pMDI in asthmatic children (6–<12 years) by Pearlman, David S., MD, Eckerwall, Göran, MD, PhD, McLaren, Julie, MD, Lamarca, Rosa, PhD, Puu, Margareta, PhD, Gilbert, Ileen, MD, Jorup, Carin, MD, Sandin, Kristina, DDS, Lanz, Miguel J., MD

“…Abstract Background The efficacy and safety of budesonide/formoterol pressurized metered-dose inhaler (pMDI) have been demonstrated in patients with asthma at…”
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Safety profile and clinical activity of multiple subcutaneous doses of MEDI-528, a humanized anti-interleukin-9 monoclonal antibody, in two randomized phase 2a studies in subjects with asthma by Parker, Joseph M, Oh, Chad K, LaForce, Craig, Miller, S David, Pearlman, David S, Le, Chenxiong, Robbie, Gabriel J, White, Wendy I, White, Barbara, Molfino, Nestor A

“…Interleukin-9 (IL-9)-targeted therapies may offer a novel approach for treating asthmatics. Two randomized placebo-controlled studies were conducted to assess…”
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Efficacy and safety of budesonide administered by pressurized metered-dose inhaler in children with asthma by Meltzer, Eli O., MD, Pearlman, David S., MD, Eckerwall, Gӧran, MD, PhD, Uryniak, Tom, MS, DePietro, Michael, MD, Lampl, Kathy, MD

“…Abstract Background Budesonide is approved for delivery using a nebulized solution and dry-powder inhaler, but its use through a pressurized metered-dose…”
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Reproducibility of the airway response to an exercise protocol standardized for intensity, duration, and inspired air conditions, in subjects with symptoms suggestive of asthma by Anderson, Sandra D, Pearlman, David S, Rundell, Kenneth W, Perry, Claire P, Boushey, Homer, Sorkness, Christine A, Nichols, Sara, Weiler, John M

“…Exercise testing to aid diagnosis of exercise-induced bronchoconstriction (EIB) is commonly performed. Reproducibility of the airway response to a standardized…”
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Fluticasone/Formoterol Combination Therapy Compared With Monotherapy in Adolescent and Adult Patients With Mild to Moderate Asthma by Pearlman, David S., MD, LaForce, Craig F., MD, Kaiser, Kirsten, MD

“…Abstract Objectives This study investigated the efficacy and tolerability of a new asthma therapy combining fluticasone propionate and formoterol fumarate…”
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Once-daily Tiotropium Respimat® Add-on to at Least ICS Maintenance Therapy Reduces Airflow Obstruction in Patients with Symptomatic Asthma, Independent of Allergic Status by Murphy, Kevin R., MD, Pearlman, David S., MD, FAAAAI, Dahl, Ronald, MD, Paggiaro, Pierluigi, MD, Engel, Michael, MD, Moroni-Zentgraf, Petra, Lühmann, Reinhold, Kerstjens, Huib A.M., MD

“…Conclusions Once-daily tiotropium Respimat® add-on to at least ICS maintenance therapy reduces airflow obstruction in patients with mild to severe symptomatic…”
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Bronchodilator efficacy of indacaterol, a novel once-daily β2 -agonist, in patients with persistent asthma by Pearlman, David S., MD, Greos, Leon, MD, LaForce, Craig, MD, Orevillo, Chadwick J., MPH, Owen, Roger, PhD, Higgins, Mark, MD

“…Background Indacaterol is a novel once-daily inhaled β2 -agonist in development for the treatment of patients with asthma or chronic obstructive pulmonary…”
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Single-dose montelukast or salmeterol as protection against exercise-induced bronchoconstriction by Philip, George, Pearlman, David S, Villarán, César, Legrand, Catherine, Loeys, Tom, Langdon, Ronald B, Reiss, Theodore F

“…It has been previously established that montelukast provides protection against exercise-induced bronchoconstriction (EIB) after a single dose. The present…”
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Novel albuterol multidose dry powder inhaler in patients with exercise-induced bronchoconstriction: A single-dose, double-blind, randomized, 2-way crossover study by Ostrom, Nancy K, Taveras, Herminia, Iverson, Harald, Pearlman, David S

“…Abstract Background A novel, inhalation-driven, multidose dry powder inhaler (MDPI) was developed that eliminates the need to coordinate device actuation with…”
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Long-term safety and efficacy studies of epinephrine HFA metered-dose inhaler (Primatene® Mist): a two-stage randomized controlled trial by Kerwin, Edward M., Tashkin, Donald P., Korenblat, Phillip E., Greos, Leon S., Pearlman, David S., Bensch, George W., Miller, S. David, Marrs, Tony, Luo, Mary Z., Zhang, Jack Y.

“…Objective: A new epinephrine hydrofluoroalkane (HFA) asthma metered-dose inhaler (MDI) was reformulated to replace the previously marketed epinephrine…”
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Once-daily ciclesonide improves lung function and is well tolerated by patients with mild-to-moderate persistent asthma by Pearlman, David S., Berger, William E., Kerwin, Edward, LaForce, Craig, Kundu, Sudeep, Banerji, Donald

“…Inhaled corticosteroids are recommended as first-line therapy for persistent asthma. We sought to assess the efficacy and safety of ciclesonide once daily in…”
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Pathophysiology of the inflammatory response by Pearlman, David S.

“…Airway allergic reactions enlist diverse cells and a multitude of chemical mediators that are responsible for the clinical symptoms of allergic rhinitis and…”
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The effect of GSK2190915, a 5-lipoxygenase-activating protein inhibitor, on exercise-induced bronchoconstriction by Kent, Sandra E, Bentley, Jane H, Miller, David, Sterling, Richard, Menendez, Rogelio, Tarpay, Martha, Pearlman, David S, Norris, Virginia

“…Exercise-induced bronchoconstriction (EIB) describes the condition whereby exercise causes airflow obstruction that lasts for up to 90 minutes without…”
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Onset and duration of protection against exercise-induced bronchoconstriction by a single oral dose of montelukast by Pearlman, David S, van Adelsberg, Janet, Philip, George, Tilles, Stephen A, Busse, William, Hendeles, Leslie, Loeys, Thomas, Dass, S Balachandra, Reiss, Theodore F

“…Leukotriene modifiers have been shown to protect against exercise-induced bronchoconstriction (EIB) with repeated, chronic dosing. To study the onset and…”
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Absence of Growth Retardation in Children With Perennial Allergic Rhinitis After One Year of Treatment With Mometasone Furoate Aqueous Nasal Spray by Schenkel, Eric J, Skoner, David P, Bronsky, Edwin A, Miller, S. David, Pearlman, David S, Rooklin, Anthony, Rosen, James P, Ruff, Michael E, Vandewalker, Mark L, Wanderer, Alan, Damaraju, Chandrasekharrao V, Nolop, Keith B, Mesarina-Wicki, Barbara

“…Intranasal corticosteroids are used widely for the treatment of allergic rhinitis because they are effective and well tolerated. However, their potential to…”
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Prevention of Exercise-induced Bronchospasm in Pediatric Asthma Patients: A Comparison of Two Salmeterol Powder Delivery Devices by Bronsky, Edwin A, Pearlman, David S, Pobiner, Bonnie F, Scott, Catherine, Wang, Yonghua, Stahl, Edmundo

“…A powder formulation of salmeterol has been shown to prevent exercise-induced bronchospasm (EIB) in asthmatic children and adults; however, the delivery device…”
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Baseline Predictors of Placebo Response in Exercise-Induced Bronchoconstriction (EIB): Pooled Regression Analysis >From Three Studies of Montelukast in EIB by Philip, George, Swern, Arlene S., Smugar, Steven S., Pearlman, David S.

“…Background. Exercise-induced bronchoconstriction (EIB) can be variable in its presentation and severity. Evaluating patterns of placebo response and…”
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Protection Against Exercise-Induced Bronchoconstriction Two Hours After a Single Oral Dose of Montelukast by Philip, George, Villarán, Cesar, Pearlman, David S., Loeys, Tom, Dass, S. Balachandra, Reiss, Theodore F.

“…The objective of this double-blind cross-over study was to evaluate montelukast for the prevention of exercise-induced bronchoconstriction (EIB). Sixty-two…”
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