Search Results - "Pearl, Ronald G."

Efficacy and Safety of Epoetin Alfa in Critically Ill Patients by Corwin, Howard L, Corwin, Michael J, Gettinger, Andrew, Fabian, Timothy C, May, Addison, Pearl, Ronald G, Heard, Stephen, An, Robert, Bowers, Peter J, Burton, Paul, Klausner, Mark A

“…In this randomized, placebo-controlled trial, the investigators administered epoetin alfa or placebo to 1460 medical, surgical, or trauma patients between 48…”
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Erythropoietin and organ protection: lessons from negative clinical trials by Pearl, Ronald G

“…Based on its pleiotropic effects, erythropoietin can decrease inflammation, oxidative stress, and apoptosis. Erythropoietin provides organ protection for the…”
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The CRIT Study: Anemia and blood transfusion in the critically ill: Current clinical practice in the United States by CORWIN, Howard L, GETTINGER, Andrew, PEARL, Ronald G, FINK, Mitchell P, LEVY, Mitchell M, ABRAHAM, Edward, MACINTYRE, Neil R, SHABOT, M. Michael, DUH, Mei-Sheng, SHAPIRO, Marc J

“…To quantify the incidence of anemia and red blood cell (RBC) transfusion practice in critically ill patients and to examine the relationship of anemia and RBC…”
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Evaluation of the efficacy and safety of amustaline/glutathione pathogen-reduced RBCs in complex cardiac surgery: the Red Cell Pathogen Inactivation (ReCePI) study-protocol for a phase 3, randomized, controlled trial by Snyder, Edward L, Sekela, Michael E, Welsby, Ian J, Toyoda, Yoshiya, Alsammak, Mohamed, Sodha, Neel R, Beaver, Thomas M, Pelletier, J Peter R, Gorham, James D, McNeil, John S, Sniecinski, Roman M, Pearl, Ronald G, Nuttall, Gregory A, Sarode, Ravi, Reece, T Brett, Kaplan, Alesia, Davenport, Robertson D, Ipe, Tina S, Benharash, Peyman, Lopez-Plaza, Ileana, Gammon, Richard R, Sadler, Patrick, Pitman, John P, Liu, Kathy, Bentow, Stanley, Corash, Laurence, Mufti, Nina, Varrone, Jeanne, Benjamin, Richard J

“…Red blood cell (RBC) transfusion is a critical supportive therapy in cardiovascular surgery (CVS). Donor selection and testing have reduced the risk of…”
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Obstructive Sleep Apnea Is an Independent Predictor of Postoperative Atrial Fibrillation in Cardiac Surgery by Wong, Jim K., MD, MS, Maxwell, Bryan G., MD, MPH, Kushida, Clete A., MD, PhD, Sainani, Kristin L., MS, PhD, Lobato, Robert L., MD, MS, Joseph Woo, Y., MD, Pearl, Ronald G., MD, PhD

“…Objective To test the hypothesis that obstructive sleep apnea (OSA) is a risk factor for development of postoperative atrial fibrillation (POAF) after cardiac…”
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Predictors of contemporary coronary artery bypass grafting outcomes by Weisel, Richard D., MD, Nussmeier, Nancy, MD, Newman, Mark F., MD, Pearl, Ronald G., MD, PhD, Wechsler, Andrew S., MD, Ambrosio, Giuseppe, MD, Pitt, Bertram, MD, Clare, Robert M., MS, Pieper, Karen S., MS, Mongero, Linda, CCP, Reece, Tammy L., MS, Yau, Terrence M., MD, Fremes, Stephen, MD, Menasché, Philippe, MD, Lira, Armando, MD, Harrington, Robert A., MD, Ferguson, T. Bruce, MD

“…Objectives The study objective was to identify the predictors of outcomes in a contemporary cohort of patients from the Reduction in cardiovascular Events by…”
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Neurotensin increases mortality and mast cells reduce neurotensin levels in a mouse model of sepsis by Wada, Etsuko, Galli, Stephen J, Faix, James D, Dobner, Paul R, Pearl, Ronald G, Chen, Ching-Cheng, Zacharias, Sherma, Tsai, Mindy, Abrink, Magnus, Nishimura, Toshihiko, Metz, Martin, Rios, Eon J, Piliponsky, Adrian M, Mohanasundaram, Uma M, Wada, Keiji, Pejler, Gunnar

“…Sepsis is a complex, incompletely understood and often fatal disorder, typically accompanied by hypotension, that is considered to represent a dysregulated…”
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Tezosentan and Right Ventricular Failure in Patients With Pulmonary Hypertension Undergoing Cardiac Surgery: The TACTICS Trial by Denault, André Y., MD, PhD, Pearl, Ronald G., MD, PhD, Michler, Robert E., MD, Rao, Vivek, MD, PhD, Tsui, Steven S.L., MD, Seitelberger, Rainald, MD, Cromie, Matt, BSc, Lindberg, Elisabet, MD, D’Armini, Andrea M., MD

“…Objective To evaluate the efficacy of tezosentan in reducing the incidence of right ventricular (RV) failure and associated mortality in patients with…”
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Thrombin Activatable Fibrinolysis Inhibitor, a Potential Regulator of Vascular Inflammation by Myles, Timothy, Nishimura, Toshihiko, Yun, Thomas H., Nagashima, Mariko, Morser, John, Patterson, Andrew J., Pearl, Ronald G., Leung, Lawrence L.K.

“…The latent plasma carboxypeptidase thrombin-activable fibrinolysis inhibitor (TAFI) is activated by thrombin/thrombomodulin on the endothelial cell surface,…”
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Simvastatin rescues rats from fatal pulmonary hypertension by inducing apoptosis of neointimal smooth muscle cells by NISHIMURA, Toshihiko, VASZAR, Laszlo T, FAUL, John L, GUOHUA ZHAO, BERRY, Gerald J, LINGFANG SHI, DAOMING QIU, BENSON, Gail, PEARL, Ronald G, KAO, Peter N

“…Pulmonary vascular injury by toxins can induce neointimal formation, pulmonary arterial hypertension (PAH), right ventricular failure, and death. We showed…”
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Simvastatin Attenuates Smooth Muscle Neointimal Proliferation and Pulmonary Hypertension in Rats by Nishimura, Toshihiko, Faul, John L, Berry, Gerald J, Vaszar, Laszlo T, Qiu, Daoming, Pearl, Ronald G, Kao, Peter N

“…Hypertensive pulmonary vascular disease is characterized by abnormal proliferation of vascular endothelial and smooth muscle cells, leading to occlusion of…”
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Development of the Modern Cardiothoracic Intensive Care Unit and Current Management by Pearl, Ronald G., Cole, Sheela Pai

“…The modern cardiothoracic intensive care unit (CTICU) developed as a result of advances in critical care, cardiology, and cardiac surgery. Patients undergoing…”
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Nocturnal Low-Dose Propofol Infusion for the Management of ICU Delirium: A Case Series in Nonintubated Cardiac Surgery Patients by Wong, Jim K., MD, MS, Nikravan, Sara, MD, Maxwell, Bryan G., MD, MPH, Marques, Michael A., MD, PhD, Pearl, Ronald G., MD, PhD

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Efficacy of recombinant human erythropoietin in the critically ill patient: A randomized, double-blind, placebo-controlled trial by Corwin, Howard L, Gettinger, Andrew, Rodriguez, Robert M, Pearl, Ronald G, Gubler, K Dean, Enny, Christopher, Colton, Theodore, Corwin, Michael J

“…OBJECTIVE:To determine whether the administration of recombinant human erythropoietin (rHuEPO) to critically ill patients in the intensive care unit (ICU)…”
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Pain Management: Optimizing Patient Care Through Comprehensive, Interdisciplinary Models and Continuous Innovations by Mackey, Sean C., Pearl, Ronald G.

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CASE 7—2012 Airway Management and Perioperative Decision Making in the Patient With Severe Pulmonary Hypertension Who Requires Emergency Noncardiac Surgery by Maxwell, Bryan G., MD, MPH, Pearl, Ronald G., MD, PhD, Kudelko, Kristina T., MD, Zamanian, Roham T., MD, Hill, Charles C., MD

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Review: Noninvasive vs invasive weaning from mechanical ventilation reduces mortality in respiratory failure by Pearl, Ronald G.

“…Burns et al investigate whether noninvasive weaning reduce mortality compared with invasive weaning in mechanically ventilated patients with respiratory…”
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Endothelial Fate Mapping in Mice With Pulmonary Hypertension by Qiao, Lina, Nishimura, Toshihiko, Shi, Lingfang, Sessions, Dane, Thrasher, Ama, Trudell, James R, Berry, Gerald J, Pearl, Ronald G, Kao, Peter N

“…BACKGROUND—Pulmonary endothelial injury triggers a reparative program, which in susceptible individuals is characterized by neointima formation, vascular…”
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Future of Anesthesiology Is Perioperative Medicine: A Call for Action by Kain, Zeev N, Fitch, Jane C K, Kirsch, Jeffrey R, Mets, Berend, Pearl, Ronald G

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40-O-(2-hydroxyethyl)-rapamycin attenuates pulmonary arterial hypertension and neointimal formation in rats by NISHIMURA, Toshihiko, FAUL, John L, BERRY, Gerald J, VEVE, Isidre, PEARL, Ronald G, KAO, Peter N

“…Pneumonectomized rats develop pulmonary hypertension (PH) and pulmonary vascular neointimal formation 4 wk after monocrotaline (MCT) administration. Male…”
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