Search Results - "Pearl, D K"

Improving diagnostic accuracy and interobserver concordance in the classification and grading of primary gliomas by Coons, Stephen W., Johnson, Peter C., Scheithauer, Bernd W., Yates, Allan J., Pearl, Dennis K.

“…BACKGROUND Accurate histologic diagnosis of gliomas is fundamental to proper patient management and to the interpretation of basic and clinical investigations…”
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Diagnostic and prognostic value of glycosyltransferase mRNA in glioblastoma multiforme patients by Oblinger, J. L., Pearl, D. K., Boardman, C. L., Saqr, H., Prior, T. W., Scheithauer, B. W., Jenkins, R. B., Burger, P. C., Yates, A. J.

“…Glioblastoma multiforme (GBM) is the most common and aggressive primary human brain tumour in adults with an average survival of 11 months. The 2‐year survival…”
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Plasma cortisol levels and reactivation of latent Epstein-Barr virus in response to examination stress by Glaser, R, Pearl, D K, Kiecolt-Glaser, J K, Malarkey, W B

“…In this study, we explored the possibility that glucocorticoid hormones, known to increase under stress, might be one component of the mechanism involved in…”
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The I1307K polymorphism of the APC gene in colorectal cancer by Prior, Thomas W., Chadwick, Robert B., Papp, Audrey C., Arcot, Anuradha N., Isa, Alexandra M., Pearl, Dennis K., Stemmermann, Grant, Percesepe, Antonio, Loukola, Anu, Aaltonen, Lauri A., de la Chapelle, Albert

“…Background & Aims: Colorectal cancer is one of the most frequent cancers in humans. Recently, a germline missense mutation, I1307K, was identified in the…”
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Spectrum of small mutations in the dystrophin coding region by PRIOR, T. W, BARTOLO, C, PEARL, D. K, PAPP, A. C, SNYDER, P. J, SEDRA, M. S, BURGHES, A. H. M, MENDELL, J. R

“…Duchenne and Becker muscular dystrophies (DMD and BMD) are caused by defects in the dystrophin gene. About two-thirds of the affected patients have large…”
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Ganglioside GM1 Enhances Induction by Nerve Growth Factor of a Putative Dimer of TrkA by Farooqui, Tahira, Franklin, Teresa, Pearl, Dennis K., Yates, Allan J.

“…: GM1 enhances nerve growth factor (NGF)‐stimulated neuritogenesis and prevents apoptotic death of PC12 cells; both may be due to enhancement of TrkA…”
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Sphingosine Kinase-1 Expression Correlates With Poor Survival of Patients With Glioblastoma Multiforme: Roles of Sphingosine Kinase Isoforms in Growth of Glioblastoma Cell Lines by Van Brocklyn, James R, Jackson, Catherine A, Pearl, Dennis K, Kotur, Mark S, Snyder, Pamela J, Prior, Thomas W

“…Sphingosine-1-phosphate is a bioactive lipid that is mitogenic for human glioma cell lines by signaling through its G protein-coupled receptors. We…”
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The major histocompatibility complex-related Fc receptor for IgG (FcRn) binds albumin and prolongs its lifespan by Chaudhury, Chaity, Mehnaz, Samina, Robinson, John M, Hayton, William L, Pearl, Dennis K, Roopenian, Derry C, Anderson, Clark L

“…The inverse relationship between serum albumin concentration and its half-life suggested to early workers that albumin would be protected from a catabolic fate…”
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A review and predictive models of ganglioside uptake by biological membranes by Saqr, H E, Pearl, D K, Yates, A J

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THE INCIDENCE OF THE GENE FOR THERMOLABILE METHYLENE TETRAHYDROFOLATE REDUCTASE IN AFRICAN AMERICANS by McAndrew, Patricia E, Brandt, John T, Pearl, Dennis K, Prior, Thomas W

“…Increased levels of homocysteine have been linked to both arterial and venous thromboembolic problems (1,2). Homocystinuria is a relatively rare disorder…”
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Time of conscious intention to act in relation to onset of cerebral activity (readiness-potential). The unconscious initiation of a freely voluntary act by Libet, B, Gleason, C A, Wright, E W, Pearl, D K

“…The recordable cerebral activity (readiness-potential, RP) that precedes a freely voluntary, fully endogenous motor act was directly compared with the…”
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Some statistical methods for phylogenetic trees with application to HIV disease by Critchlow, D.E, Li, Shuying, Nourijelyani, K, Pearl, D.K

“…Phylogenetic trees are commonly used to describe the evolutionary history of a group of species, but may also be used to study an evolving virus such as HIV…”
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Bayesian modelling of the dynamics of hepatotoxicity by Li, Q., Shen, X., Pearl, D. K.

“…Hepatotoxicity (liver damage) is a common problem in drug treatment trials but is observed only indirectly through biomarkers measured in the blood. This…”
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Control of the transition from sensory detection to sensory awareness in man by the duration of a thalamic stimulus. The cerebral 'time-on' factor by Libet, B, Pearl, D K, Morledge, D E, Gleason, C A, Hosobuchi, Y, Barbaro, N M

“…A 'time-on' theory to explain the cerebral distinction between conscious and unconscious mental functions proposes that a substantial minimum duration…”
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Glycolipid Markers of Astrocytomas and Oligodendrogliomas by Yates, Allan J, Comas, Theodore, Scheithauer, Bernd W, Burger, Peter C, Pearl, Dennis K

“…Neutral glycolipids and gangliosides were analyzed in 149 astrocytomas (A), 46 oligodendrogliomas (O), and 21 oligoastrocytomas (OA) to determine if specific…”
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Mutational spectrum in the neurofibromatosis type 2 gene in sporadic and familial schwannomas by WELLING, D. B, GUIDA, M, GOLL, F, PEARL, D. K, GLASSCOCK, M. E, PAPPAS, D. G, LINTHICUM, F. H, ROGERS, D, PRIOR, T. W

“…Using a heteroduplex approach and direct sequencing, we have completed the screening of approximately 88% of the neurofibromatosis type 2 (NF2)-coding sequence…”
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Neurological manifestations of decompression illness in recreational divers - the Cozumel experience by Newton, H B, Padilla, W, Burkart, J, Pearl, D K

“…Neurological signs and symptoms are common in recreational divers with decompression illness (DCI). The spectrum of neurological manifestations, temporal…”
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Small Cell Architecture—A Histological Equivalent of EGFR Amplification in Glioblastoma Multiforme? by BURGER, PETER C, PEARL, DENNIS K, ALDAPE, KENNETH, YATES, ALLAN J, SCHEITHAUER, BERND W, PASSE, SANDRA M, JENKINS, ROBERT B, JAMES, C DAVID

“…Although there is much written about the molecular definitions of “primary” glioblastomas (GBM), there is little known about the histological features of this…”
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The influence of academic stress and season on 24-hour concentrations of growth hormone and prolactin by Malarkey, W B, Hall, J C, Pearl, D K, Kiecolt-Glaser, J K, Glaser, R

“…Stress has been considered a physiological regulator of GH and PRL secretion in humans. The stressors used in studies have often been extreme. The influence of…”
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Gangliosides as diagnostic markers of human astrocytomas and primitive neuroectodermal tumors by Sung, C C, Pearl, D K, Coons, S W, Scheithauer, B W, Johnson, P C, Yates, A J

“…Limitations of classification schemes for brain tumors based solely on morphology have stimulated searches for molecular markers of nosologic and prognostic…”
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