Search Results - "Pearce, R"

Epitaxially grown graphene based gas sensors for ultra sensitive NO₂ detection by Pearce, R, Iakimov, T, Andersson, M, Hultman, L, Spetz, A. Lloyd, Yakimova, R

“…Epitaxially grown single layer and multi layer graphene on SiC devices were fabricated and compared for response towards NO₂. Due to electron donation from…”
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Peptide Targeted Lipid Nanoparticles for Anticancer Drug Delivery by Pearce, Timothy R., Shroff, Kamlesh, Kokkoli, Efrosini

“…Encapsulating anticancer drugs in nanoparticles has proven to be an effective mechanism to alter the pharmacokinetic and pharmacodynamic profiles of the drugs,…”
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Neighborhood Environments and Socioeconomic Inequalities in Mental Well-Being by Mitchell, Richard J., PhD, Richardson, Elizabeth A., PhD, Shortt, Niamh K., PhD, Pearce, Jamie R., PhD

“…Introduction It has been suggested that socioeconomic inequalities in health might be reduced among populations with good access to green space. However, the…”
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The CYP2D6 Activity Score: Translating Genotype Information into a Qualitative Measure of Phenotype by Gaedigk, A, Simon, SD, Pearce, RE, Bradford, LD, Kennedy, MJ, Leeder, JS

“…Inferring CYP2D6 phenotype from genotype is increasingly challenging, considering the growing number of alleles and their range of activity. This complexity…”
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An inventory of galaxies in cosmic filaments feeding galaxy clusters: galaxy groups, backsplash galaxies, and pristine galaxies by Kuchner, Ulrike, Haggar, Roan, Aragón-Salamanca, Alfonso, Pearce, Frazer R, Gray, Meghan E, Rost, Agustín, Cui, Weiguang, Knebe, Alexander, Yepes, Gustavo

“…ABSTRACT Galaxy clusters grow by accreting galaxies from the field and along filaments of the cosmic web. As galaxies are accreted they are affected by their…”
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The relationship between wealth and loneliness among older people across Europe: Is social participation protective? by Niedzwiedz, Claire L., Richardson, Elizabeth A., Tunstall, Helena, Shortt, Niamh K., Mitchell, Richard J., Pearce, Jamie R.

“…1. Examine the relationship between household wealth, social participation and loneliness among older people across Europe. 2. Investigate whether…”
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The control of carbonate mineral Mg isotope composition by aqueous speciation: Theoretical and experimental modeling by Schott, Jacques, Mavromatis, Vasileios, Fujii, Toshiyuki, Pearce, Christopher R., Oelkers, Eric H.

“…The magnesium isotope compositions of sedimentary carbonates are widely used to investigate the geochemical cycling of this element in seawater. Density…”
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Axonal myelin decrease in the splenium in major depressive disorder by Williams, Matthew R., Sharma, P., Macdonald, C., Pearce, R. K. B., Hirsch, S. R., Maier, M.

“…The corpus callosum has become a key area of interest for researchers in severe mental illness. Disruptions in fractional anisotropy in the callosum have been…”
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Characterization of PF-4708671, a novel and highly specific inhibitor of p70 ribosomal S6 kinase (S6K1) by Pearce, Laura R, Alton, Gordon R, Richter, Daniel T, Kath, John C, Lingardo, Laura, Chapman, Justin, Hwang, Catherine, Alessi, Dario R

“…S6K1 (p70 ribosomal S6 kinase 1) is activated by insulin and growth factors via the PI3K (phosphoinositide 3-kinase) and mTOR (mammalian target of rapamycin)…”
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TheThreeHundred Project: ram pressure and gas content of haloes and subhaloes in the phase-space plane by Arthur, Jake, Pearce, Frazer R, Gray, Meghan E, Knebe, Alexander, Cui, Weiguang, Elahi, Pascal J, Power, Chris, Yepes, Gustavo, Arth, Alexander, De Petris, Marco, Dolag, Klaus, Garratt-Smithson, Lilian, Old, Lyndsay J, Rasia, Elena, Stevens, Adam R H

“…Abstract We use TheThreeHundred project, a suite of 324 resimulated massive galaxy clusters embedded in a broad range of environments, to investigate (i) how…”
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Bringing CLARITY to the human brain: visualization of Lewy pathology in three dimensions by Liu, A. K. L., Hurry, M. E. D., Ng, O.T. W., DeFelice, J., Lai, H. M., Pearce, R. K. B., Wong, G. T-C., Chang, R. C-C., Gentleman, S. M.

“…Aims CLARITY is a novel technique which enables three‐dimensional visualization of immunostained tissue for the study of circuitry and spatial interactions…”
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Magnesium isotope fractionation during hydrothermal seawater-basalt interaction by Voigt, Martin, Pearce, Christopher R., Fries, David M., Baldermann, Andre, Oelkers, Eric H.

“…Fluid-rock interactions in hydrothermal systems at or near mid-oceanic ridges (MOR) play a major role in determining the composition of the oceanic crust and…”
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The effect of particulate dissolution on the neodymium (Nd) isotope and Rare Earth Element (REE) composition of seawater by Pearce, Christopher R., Jones, Morgan T., Oelkers, Eric H., Pradoux, Catherine, Jeandel, Catherine

“…The exchange of material between particulates and seawater along the continental margins, a process commonly referred to as boundary exchange, is thought to…”
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Protor-1 is required for efficient mTORC2-mediated activation of SGK1 in the kidney by Pearce, Laura R, Sommer, Eeva M, Sakamoto, Kei, Wullschleger, Stephan, Alessi, Dario R

“…The mTOR (mammalian target of rapamycin) protein kinase is an important regulator of cell growth and is a key target for therapeutic intervention in cancer…”
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The dorsal motor nucleus of the vagus is not an obligatory trigger site of Parkinson's disease: a critical analysis of α-synuclein staging by Kalaitzakis, M. E., Graeber, M. B., Gentleman, S. M., Pearce, R. K. B.

“…Aims: It has been proposed that alpha‐synuclein (αSyn) pathology in Parkinson's disease (PD) spreads in a predictable caudo‐rostral way with the earliest…”
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Investigation of Seawater Reverse Osmosis Fouling and Its Relationship To Pretreatment Type by Kumar, Manish, Adham, Samer S, Pearce, William R

“…Desalination of seawater using reverse osmosis (RO) technology is an important option available to water-scarce coastal regions. A major challenge to seawater…”
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Identification of Protor as a novel Rictor-binding component of mTOR complex-2 by Pearce, Laura R, Huang, Xu, Boudeau, Jérôme, Pawłowski, Rafał, Wullschleger, Stephan, Deak, Maria, Ibrahim, Adel F M, Gourlay, Robert, Magnuson, Mark A, Alessi, Dario R

“…The mTOR (mammalian target of rapamycin) protein kinase is an important regulator of cell growth. Two complexes of mTOR have been identified: complex 1,…”
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DNA nanotubes and helical nanotapes via self-assembly of ssDNA-amphiphiles by Pearce, Timothy R, Kokkoli, Efrosini

“…DNA nanotubes were created using molecular self-assembly of single-stranded DNA (ssDNA)-amphiphiles composed of a hydrophobic dialkyl tail and polycarbon…”
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nIFTy galaxy cluster simulations – I. Dark matter and non-radiative models by Sembolini, Federico, Yepes, Gustavo, Pearce, Frazer R., Knebe, Alexander, Kay, Scott T., Power, Chris, Cui, Weiguang, Beck, Alexander M., Borgani, Stefano, Dalla Vecchia, Claudio, Davé, Romeel, Elahi, Pascal Jahan, February, Sean, Huang, Shuiyao, Hobbs, Alex, Katz, Neal, Lau, Erwin, McCarthy, Ian G., Murante, Guiseppe, Nagai, Daisuke, Nelson, Kaylea, Newton, Richard D. A., Perret, Valentin, Puchwein, Ewald, Read, Justin I., Saro, Alexandro, Schaye, Joop, Teyssier, Romain, Thacker, Robert J.

“…We have simulated the formation of a galaxy cluster in a Λ cold dark matter universe using 13 different codes modelling only gravity and non-radiative…”
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Disturbed sleep in Parkinson's disease: anatomical and pathological correlates by Kalaitzakis, M. E., Gentleman, S. M., Pearce, R. K. B.

“…Aims Abnormal sleep is a common feature of Parkinson's disease (PD) and prodromal disorders of sleep are frequent (e.g. restless legs syndrome and rapid eye…”
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