Search Results - "Pearce, Hannah"

Repair of complex ovine segmental mandibulectomy utilizing customized tissue engineered bony flaps by Watson, Emma, Pearce, Hannah A, Hogan, Katie J, van Dijk, Natasja W M, Smoak, Mollie M, Barrios, Sergio, Smith, Brandon T, Tatara, Alexander M, Woernley, Timothy C, Shum, Jonathan, Pearl, Craig B, Melville, James C, Ho, Tang, Hanna, Issa A, Demian, Nagi, van den Beucken, Jeroen J J P, Jansen, John A, Wong, Mark E, Mikos, Antonios G

“…Craniofacial defects require a treatment approach that provides both robust tissues to withstand the forces of mastication and high geometric fidelity that…”
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Advances in Nanotechnology for the Treatment of Osteoporosis by Barry, Mikayla, Pearce, Hannah, Cross, Lauren, Tatullo, Marco, Gaharwar, Akhilesh K.

“…Osteoporosis is a degenerative bone disease commonly related to aging. With an increase in life expectancies worldwide, the prevalence of the disease is…”
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The effect of multi-material architecture on the ex vivo osteochondral integration of bioprinted constructs by Bedell, Matthew L., Wang, Ziwen, Hogan, Katie J., Torres, Angelica L., Pearce, Hannah A., Chim, Letitia K., Grande-Allen, K. Jane, Mikos, Antonios G.

“…Extrusion bioprinted constructs for osteochondral tissue engineering were fabricated to study the effect of multi-material architecture on encapsulated human…”
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Microfluidic devices for disease modeling in muscle tissue by Smoak, Mollie M., Pearce, Hannah A., Mikos, Antonios G.

“…Microfluidic devices have advanced significantly in recent years and are a promising technology for the field of tissue engineering. Highly sophisticated…”
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Low-Fouling and Biodegradable Protein-Based Particles for Thrombus Imaging by Bonnard, Thomas, Jayapadman, Anand, Putri, Jasmine A, Cui, Jiwei, Ju, Yi, Carmichael, Catherine, Angelovich, Thomas A, Cody, Stephen H, French, Shauna, Pascaud, Karline, Pearce, Hannah A, Jagdale, Shweta, Caruso, Frank, Hagemeyer, Christoph E

“…Nanomedicine holds great promise for vascular disease diagnosis and specific therapy, yet rapid sequestration by the mononuclear phagocytic system limits the…”
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Evaluation of tissue integration of injectable, cell‐laden hydrogels of cocultures of mesenchymal stem cells and articular chondrocytes with an ex vivo cartilage explant model by Kim, Yu Seon, Mehta, Shail M., Guo, Jason L., Pearce, Hannah A., Smith, Brandon T., Watson, Emma, Koons, Gerry L., Navara, Adam M., Lam, Johnny, Grande‐Allen, K. Jane, Mikos, Antonios G.

“…This study investigated the chondrogenic activity of encapsulated mesenchymal stem cells (MSCs) and articular chondrocytes (ACs) and its impact on the…”
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Chondrogenesis of cocultures of mesenchymal stem cells and articular chondrocytes in poly(l-lysine)-loaded hydrogels by Kim, Yu Seon, Chien, Athena J., Guo, Jason L., Smith, Brandon T., Watson, Emma, Pearce, Hannah A., Koons, Gerry L., Navara, Adam M., Lam, Johnny, Scott, David W., Grande-Allen, K. Jane, Mikos, Antonios G.

“…This work investigated the effect of poly(l-lysine) (PLL) molecular weight and concentration on chondrogenesis of cocultures of mesenchymal stem cells (MSCs)…”
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18F Site-Specific Labelling of a Single-Chain Antibody against Activated Platelets for the Detection of Acute Thrombosis in Positron Emission Tomography by Ardipradja, Katie S., Wichmann, Christian W., Hickson, Kevin, Rigopoulos, Angela, Alt, Karen M., Pearce, Hannah A., Wang, Xiaowei, O’Keefe, Graeme, Scott, Andrew M., Peter, Karlheinz, Hagemeyer, Christoph E., Ackermann, Uwe

“…Positron emission tomography is the imaging modality of choice when it comes to the high sensitivity detection of key markers of thrombosis and inflammation,…”
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Bilayered, peptide-biofunctionalized hydrogels for in vivo osteochondral tissue repair by Guo, Jason L., Kim, Yu Seon, Koons, Gerry L., Lam, Johnny, Navara, Adam M., Barrios, Sergio, Xie, Virginia Y., Watson, Emma, Smith, Brandon T., Pearce, Hannah A., Orchard, Elysse A., van den Beucken, Jeroen J.J.P., Jansen, John A., Wong, Mark E., Mikos, Antonios G.

“…Osteochondral defects present a unique clinical challenge due to their combination of phenotypically distinct cartilage and bone, which require specific,…”
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Collagen-Targeted Theranostic Nanosponges for Delivery of the Matrix Metalloproteinase 14 Inhibitor Naphthofluorescein by Wang, Ting-Yi, Kendrick-Williams, Laken L, Choy, Mei Y, Gilmore, Kelly A, Bonnard, Thomas, Pearce, Hannah A, Law, Lok Soon, Carmichael, Iska, Cody, Stephen H, Alt, Karen, Hagemeyer, Christoph E, Harth, Eva

“…We report the development of a theranostic collagen targeted cell penetrating drug delivery system toward treatment of cardiovascular disease. Caused by the…”
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Thermogelling hydrogel charge and lower critical solution temperature influence cellular infiltration and tissue integration in an ex vivo cartilage explant model by Pearce, Hannah A., Swain, Joseph W. R., Victor, Luis Hector, Hogan, Katie J., Jiang, Emily Y., Bedell, Matthew L., Navara, Adam M., Farsheed, Adam, Kim, Yu Seon, Guo, Jason L., Hartgerink, Jeffrey D., Grande‐Allen, K. Jane, Mikos, Antonios G.

“…Thermogelling hydrogels based on poly(N‐isopropyl acrylamide) (p[NiPAAm]) and crosslinked with a peptide‐bearing macromer poly(glycolic acid)‐poly(ethylene…”
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Localized mandibular infection affects remote in vivo bioreactor bone generation by Watson, Emma, Smith, Brandon T., Smoak, Mollie M., Tatara, Alexander M., Shah, Sarita R., Pearce, Hannah A., Hogan, Katie J., Shum, Jonathan, Melville, James C., Hanna, Issa A., Demian, Nagi, Wenke, Joseph C., Bennett, George N., van den Beucken, Jeroen J.J.P., Jansen, John A., Wong, Mark E., Mikos, Antonios G.

“…Mandibular reconstruction requires functional and aesthetic repair and is further complicated by contamination from oral and skin flora. Antibiotic-releasing…”
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Prevention of Oxygen Inhibition of PolyHIPE Radical Polymerization Using a Thiol-Based Cross-Linker by Whitely, Michael E, Robinson, Jennifer L, Stuebben, Melissa C, Pearce, Hannah A, McEnery, Madison A.P, Cosgriff-Hernandez, Elizabeth

“…Polymerized high internal phase emulsions (polyHIPEs) are highly porous constructs currently under investigation as tissue engineered scaffolds. We previously…”
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Development of a modular, biocompatible thiolated gelatin microparticle platform for drug delivery and tissue engineering applications by Pearce, Hannah A, Kim, Yu Seon, Watson, Emma, Bahrami, Kiana, Smoak, Mollie M, Jiang, Emily Y, Elder, Michael, Shannon, Tate, Mikos, Antonios G

“…Abstract The field of biomaterials has advanced significantly in the past decade. With the growing need for high-throughput manufacturing and screening, the…”
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Site-Specific Glycation and Chemo-enzymatic Antibody Sortagging for the Retargeting of rAAV6 to Inflamed Endothelium by Pearce, Hannah A., Qian, Hongwei, Connell, Timothy U., Huang, Dexing, Gottstein, Claudia, Donnelly, Paul S., Peter, Karlheinz, Gregorevic, Paul, Hagemeyer, Christoph E.

“…Gene therapy holds great potential for conditions such as cardiovascular disease, including atherosclerosis and also vascular cancers, yet available vectors…”
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Evaluating the physicochemical effects of conjugating peptides into thermogelling hydrogels for regenerative biomaterials applications by Pearce, Hannah A, Jiang, Emily Y, Swain, Joseph W R, Navara, Adam M, Guo, Jason L, Kim, Yu Seon, Woehr, Andrew, Hartgerink, Jeffrey D, Mikos, Antonios G

“…Abstract Thermogelling hydrogels, such as poly(N-isopropylacrylamide) [P(NiPAAm)], provide tunable constructs leveraged in many regenerative biomaterial…”
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Prevention of Oxygen Inhibition of PolyHIPE Radical Polymerization using a Thiol-based Crosslinker by Whitely, Michael E, Robinson, Jennifer L, Stuebben, Melissa C, Pearce, Hannah A, McEnery, Madison A P, Cosgriff-Hernandez, Elizabeth

“…Polymerized high internal phase emulsions (polyHIPEs) are highly porous constructs currently under investigation as tissue engineered scaffolds. We previously…”
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Thermogelling materials and their important role in biomedical engineering applications by Pearce, Hannah A., Mikos, Antonios G.

“…Thermogelling materials describe a group of materials which undergo a sol to gel transformation in response to temperature. This can occur either by surpassing…”
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Sequential Thiol–Ene and Tetrazine Click Reactions for the Polymerization and Functionalization of Hydrogel Microparticles by Jivan, Faraz, Yegappan, Ramanathan, Pearce, Hannah, Carrow, James K, McShane, Michael, Gaharwar, Akhilesh K, Alge, Daniel L

“…Click chemistry is a versatile tool for the synthesis and functionalization of polymeric biomaterials. Here, we describe a versatile new strategy for producing…”
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Machine Learning and Medical Devices: The Next Step for Tissue Engineering by Pearce, Hannah A., Mikos, Antonios G.

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