Search Results - "Pearce, Clive"
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1
Elucidation of the biosynthetic pathways of boldenone in the equine testis
Published in Steroids (01-06-2019)“…•Boldenone and boldenone are naturally present in the equine testis.•Labelled boldenone was formed from labelled testosterone and androstenedione.•Labelled…”
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2
The intravenous pharmacokinetics of butorphanol and detomidine dosed in combination compared with individual dose administrations to exercised horses
Published in Journal of veterinary pharmacology and therapeutics (01-03-2020)“…In equine and racing practice, detomidine and butorphanol are commonly used in combination for their sedative properties. The aim of the study was to produce…”
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3
Comparative in vitro metabolism of the ‘designer’ steroid estra-4,9-diene-3,17-dione between the equine, canine and human: Identification of target metabolites for use in sports doping control
Published in Steroids (01-10-2010)“…Effective detection of the abuse of androgenic-anabolic steroids in human and animal sports often requires knowledge of the drug's metabolism in order to…”
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4
Detection of fluticasone propionate in horse plasma and urine following inhaled administration
Published in Drug testing and analysis (01-05-2013)“…Fluticasone propionate (FP) is an anti‐inflammatory agent with topical and inhaled applications commonly used in the treatment of asthma in steroid‐dependent…”
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5
Analysis of methyloxime derivatives of intact esters of testosterone and boldenone in equine plasma using ultra high performance liquid chromatography tandem mass spectrometry
Published in Drug testing and analysis (01-04-2011)“…Analysis of equine plasma samples to detect the abuse of anabolic steroids can be complicated when the parent steroid is endogenous to the animal. Anabolic…”
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6
UPLC-MS/MS Method for the Identification of Recombinant Human Erythropoietin Analogues in Horse Plasma and Urine
Published in Chromatographia (01-10-2011)“…Recombinant human erythropoietin (rhEPO) analogues are known to have been used in horse sports for their assumed performance enhancing properties. Recently,…”
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7
Microbiological production of omeprazole metabolites by Cunninghamella elegans
Published in Journal of molecular catalysis. B, Enzymatic (04-08-2006)“…Incubation of Cunninghamella elegans ATCC 9245 and the anti ulcer drug omeprazole allowed putative fungal metabolites to be isolated in sufficient quantities…”
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8
Investigations into the feasibility of routine ultra high performance liquid chromatography–tandem mass spectrometry analysis of equine hair samples for detecting the misuse of anabolic steroids, anabolic steroid esters and related compounds
Published in Analytica chimica acta (17-07-2013)“…•Analysis of 22 anabolic steroids and related compounds in horse hair.•Detection of stanozolol and testosterone and boldenone esters in real world…”
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The use of in vitro technologies and high-resolution/accurate-mass LC-MS to screen for metabolites of 'designer' steroids in the equine
Published in Drug testing and analysis (01-01-2011)“…Detection of androgenic‐anabolic steroid abuse in equine sports requires knowledge of the drug's metabolism in order to target appropriate metabolites,…”
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10
Interlaboratory trial for the measurement of total cobalt in equine urine and plasma by ICP‐MS
Published in Drug testing and analysis (01-09-2017)“…Cobalt is an essential mineral micronutrient and is regularly present in equine nutritional and feed supplements. Therefore, cobalt is naturally present at low…”
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11
Male antifertility compounds from Tripterygium wilfordii Hook f
Published in Contraception (Stoneham) (01-04-1993)“…Extracts of the Chinese medicinal plant, Tripterygium wilfordii, cause reversible infertility in male animals. Sub-fractionation studies have now revealed that…”
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12
Isolation and structure determination of terminalin A toxic condensed tannin from Terminalia oblongata
Published in Natural toxins (1994)“…Terminalia oblongata (yellow wood) is a small deciduous tree growing over an area of central Queensland that supports a large proportion of this state's cattle…”
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13
The effect of crystal defects on the chemical properties of selected metals
Published 01-01-1971“…It is well known that cold working of a crystalline solid leads to high concentrations of dislocations in the lattice. In this state, the solid contains…”
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Dissertation