Search Results - "Pearce, Cadence"
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Molecular Transducers of Physical Activity Consortium (MoTrPAC): Mapping the Dynamic Responses to Exercise
Published in Cell (25-06-2020)“…Exercise provides a robust physiological stimulus that evokes cross-talk among multiple tissues that when repeated regularly (i.e., training) improves…”
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Dynamic regulation of inter-organelle communication by ubiquitylation controls skeletal muscle development and disease onset
Published in eLife (11-07-2023)“…Ubiquitin-proteasome system (UPS) dysfunction is associated with the pathology of a wide range of human diseases, including myopathies and muscular atrophy…”
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Systems‐level Adaptation to Exercise Training in Rat Heart and Liver
Published in The FASEB journal (01-05-2021)“…Background Exercise training promotes metabolic wellness, prevents many disorders, and has therapeutic benefits, such as in cardiovascular disease and…”
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Temporal dynamics of the multi-omic response to endurance exercise training
Published in Nature (London) (02-05-2024)“…Regular exercise promotes whole-body health and prevents disease, but the underlying molecular mechanisms are incompletely understood 1 – 3 . Here, the…”
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SND1 binds SARS-CoV-2 negative-sense RNA and promotes viral RNA synthesis through NSP9
Published in Cell (26-10-2023)“…Regulation of viral RNA biogenesis is fundamental to productive SARS-CoV-2 infection. To characterize host RNA-binding proteins (RBPs) involved in this…”
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The impact of exercise on gene regulation in association with complex trait genetics
Published in Nature communications (01-05-2024)“…Endurance exercise training is known to reduce risk for a range of complex diseases. However, the molecular basis of this effect has been challenging to study…”
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