Search Results - "Pearce, Brad"
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1
Mendelian randomization of cytokines in schizophrenia and depression: What does this tell us about causal chains in these illnesses?
Published in Brain, behavior, and immunity (01-01-2022)Get full text
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2
Maternal immune activation: reporting guidelines to improve the rigor, reproducibility, and transparency of the model
Published in Neuropsychopharmacology (New York, N.Y.) (01-01-2019)“…The 2017 American College of Neuropychopharmacology (ACNP) conference hosted a Study Group on 4 December 2017, Establishing best practice guidelines to improve…”
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3
The Relationship Between Toxoplasma Gondii Infection and Mood Disorders in the Third National Health and Nutrition Survey
Published in Biological psychiatry (1969) (15-08-2012)“…Background Toxoplasma gondii (T. gondii) is a neurotropic protozoan parasite that causes persistent infection in humans. A substantial literature suggests that…”
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4
Infection and inflammation in schizophrenia and bipolar disorder: a genome wide study for interactions with genetic variation
Published in PloS one (17-03-2015)“…Inflammation and maternal or fetal infections have been suggested as risk factors for schizophrenia (SZ) and bipolar disorder (BP). It is likely that such…”
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5
Cortisol Levels and Risk for Psychosis: Initial Findings from the North American Prodrome Longitudinal Study
Published in Biological psychiatry (1969) (15-09-2013)“…Background Studies of biomarkers of hypothalamic-pituitary-adrenal activity indicate that psychotic disorders are associated with elevated cortisol. This study…”
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6
Comparison of autonomic stress reactivity in young healthy versus aging subjects with heart disease
Published in PloS one (08-05-2019)“…The autonomic response to acute emotional stress can be highly variable, and pathological responses are associated with increased risk of adverse…”
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The association of Toxoplasma gondii infection with neurocognitive deficits in a population-based analysis
Published in Social Psychiatry and Psychiatric Epidemiology (01-06-2014)“…Purpose To examine the relationship between infection with Toxoplasma gondii (toxo) and cognition. Methods Multivariate logistic regression was used to test…”
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Weathering the storm; a review of pre-pregnancy stress and risk of spontaneous abortion
Published in Psychoneuroendocrinology (01-06-2018)“…•This conceptual review proposes mechanisms driving the Weathering Effect.•Danger signaling may mediate psychosocial effects on spontaneous abortion…”
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Brain Correlates of Mental Stress-Induced Myocardial Ischemia
Published in Psychosomatic medicine (01-07-2018)“…Coronary artery disease (CAD) is a major cause of morbidity and mortality, and despite important advances in our understanding of this disorder, the underlying…”
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10
Comparison of cognitive performance measures in individuals with systemic lupus erythematosus
Published in Lupus science & medicine (16-04-2024)“…ObjectiveCognitive impairment is a common complaint in SLE, but approaches to measuring cognitive performance objectively vary. Leveraging data collected in a…”
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Posttraumatic stress disorder is associated with enhanced interleukin-6 response to mental stress in subjects with a recent myocardial infarction
Published in Brain, behavior, and immunity (01-01-2019)“…•MI patients with PTSD show enhanced IL-6 response to stress than those without PTSD.•This effect is mainly driven by the re-experiencing symptom cluster of…”
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Higher Activation of the Rostromedial Prefrontal Cortex During Mental Stress Predicts Major Cardiovascular Disease Events in Individuals With Coronary Artery Disease
Published in Circulation (New York, N.Y.) (04-08-2020)“…Psychological stress is a risk factor for major adverse cardiovascular events (MACE) in individuals with coronary artery disease. Certain brain regions that…”
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Associations Between Inflammation, Cardiovascular Regenerative Capacity, and Cardiovascular Events: A Cohort Study
Published in Arteriosclerosis, thrombosis, and vascular biology (01-11-2021)“…Circulating progenitor cells possess immune modulatory properties and might mitigate inflammation that is characteristic of patients with coronary artery…”
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Sex differences in the inflammatory response to stress and risk of adverse cardiovascular outcomes among patients with coronary heart disease
Published in Brain, behavior, and immunity (01-11-2020)“…•First to study inflammatory response to stress and adverse cardiovascular events.•We found clear sex differences.•Higher IL-6 and MCP-1 stress response was…”
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Polygenic risk scores differentiate schizophrenia patients with toxoplasma gondii compared to toxoplasma seronegative patients
Published in Comprehensive psychiatry (01-05-2021)“…Schizophrenia (SCZ) is an etiologically heterogeneous disease with genetic and environmental risk factors (e.g., Toxoplasma gondii infection) differing among…”
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Genetic risk for hospitalization of African American patients with severe mental illness reveals HLA loci
Published in Frontiers in psychiatry (26-02-2024)“…Mood disorders such as major depressive and bipolar disorders, along with posttraumatic stress disorder (PTSD), schizophrenia (SCZ), and other psychotic…”
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Stress-Induced Autonomic Dysfunction is Associated With Mental Stress-Induced Myocardial Ischemia in Patients With Coronary Artery Disease
Published in Circulation. Cardiovascular imaging (01-06-2024)“…Mental stress-induced myocardial ischemia (MSIMI) is associated with adverse cardiovascular outcomes in individuals with coronary artery disease, but the…”
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Genome-wide association study in two populations to determine genetic variants associated with Toxoplasma gondii infection and relationship to schizophrenia risk
Published in Progress in neuro-psychopharmacology & biological psychiatry (08-06-2019)“…T. gondii (TOXO) infects over one billion people worldwide, yet the literature lacks a Genome Wide Association Study (GWAS) focused on genetic variants…”
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Identification of fetal and maternal single nucleotide polymorphisms in candidate genes that predispose to spontaneous preterm labor with intact membranes
Published in American journal of obstetrics and gynecology (01-05-2010)“…Objective The purpose of this study was to determine whether maternal/fetal single nucleotide polymorphisms (SNPs) in candidate genes are associated with…”
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Telomere Shortening, Regenerative Capacity, and Cardiovascular Outcomes
Published in Circulation research (31-03-2017)“…RATIONALE:Leukocyte telomere length (LTL) is a biological marker of aging, and shorter LTL is associated with adverse cardiovascular outcomes. Reduced…”
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