Search Results - "Peale, F V"
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Expression of vascular endothelial growth factor, hypoxia inducible factor 1α, and carbonic anhydrase IX in human tumours
Published in Journal of clinical pathology (01-05-2004)“…Aims: To measure vascular endothelial growth factor (VEGF-A) mRNA in a large, diverse cohort of tumours and to investigate whether VEGF-A expression is…”
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2
FIZZ1, a novel cysteine-rich secreted protein associated with pulmonary inflammation, defines a new gene family
Published in The EMBO journal (01-08-2000)“…Bronchoalveolar lavage fluid from mice with experimentally induced allergic pulmonary inflammation contains a novel 9.4 kDa cysteine‐rich secreted protein,…”
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3
Phase I study of the checkpoint kinase 1 inhibitor GDC-0575 in combination with gemcitabine in patients with refractory solid tumors
Published in Annals of oncology (01-05-2018)“…Checkpoint kinase 1 (Chk1) inhibition following chemotherapy-elicited DNA damage overrides cell cycle arrest and induces mitotic catastrophe and cell death…”
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4
Quantitative analysis of colorectal tissue microarrays by immunofluorescence and in situ hybridization
Published in The Journal of pathology (01-08-2003)“…The accuracy and reliability of in situ studies may be compromised by qualitative interpretations. Quantitation imposes a greater degree of objectivity, is…”
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5
Gene profiling techniques and their application in angiogenesis and vascular development
Published in The Journal of pathology (01-09-2001)“…The analysis of gene expression in specific tissues and physiological processes has evolved over the last 20 years from the painstaking identification of…”
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6
Properties of a High-Affinity DNA Binding Site for Estrogen Receptor
Published in Proceedings of the National Academy of Sciences - PNAS (01-02-1988)“…It has been shown previously that a short sequence from the 5′ regulatory region of the Xenopus laevis vitellogenin gene A2, when appropriately placed, can…”
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7
Cooperative estrogen receptor interaction with consensus or variant estrogen responsive elements in vitro
Published in Cancer research (Chicago, Ill.) (01-03-1992)“…Specific binding of estradiol-liganded, partially purified calf uterine estrogen receptor (ER) to a 38-base pair estrogen responsive element (ERE) consensus…”
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8
Detection of novel gene expression in paraffin-embedded tissues by isotopic in situ hybridization in tissue microarrays
Published in The Journal of pathology (01-09-2001)“…Correlating altered gene expression patterns with particular disease states is a critical step in understanding disease processes and developing treatment…”
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9
Dobutamine stress cine-MRI of cardiac function in the hearts of adult cardiomyocyte-specific VEGF knockout mice
Published in Journal of magnetic resonance imaging (01-10-2001)“…A mouse model of non‐necrotic vascular deficiency in the adult heart was studied using cine‐magnetic resonance imaging (MRI) and other techniques. The mice…”
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10
Expression of novel potassium channels in the chick basilar papilla
Published in Hearing research (01-11-1998)“…Ionic currents are critical for the functioning of the inner ear auditory sensory epithelium. We set out to identify and molecularly clone the genes encoding…”
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11
Vascular Endothelial Growth Factor Stimulates Bone Repair by Promoting Angiogenesis and Bone Turnover
Published in Proceedings of the National Academy of Sciences - PNAS (23-07-2002)“…Several growth factors are expressed in distinct temporal and spatial patterns during fracture repair. Of these, vascular endothelial growth factor, VEGF, is…”
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12
A microtiter well assay for quantitative measurement of estrogen receptor binding to estrogen-responsive elements
Published in Molecular endocrinology (Baltimore, Md.) (01-07-1990)“…Reproducible, rapid measurement of estrogen receptor (ER) binding to DNA was accomplished in microtiter wells treated so that ER-DNA complexes or DNA bound in…”
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13
Multiplex Display Polymerase Chain Reaction Amplifies and Resolves Related Sequences Sharing a Single Moderately Conserved Domain
Published in Analytical biochemistry (15-02-1998)“…We present a technique, multiplex display polymerase chain reaction (MD-PCR), that amplifies and resolves coding sequences from messenger RNAs sharing only a…”
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14
Rapid purification of the estrogen receptor by sequence-specific DNA affinity chromatography
Published in Biochemistry (Easton) (01-10-1989)“…Rapid purification of calf uterine estrogen receptor (ER) to near homogeneity has been accomplished by use of sequence-specific DNA affinity resin. Very high…”
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15
Stanniocalcin 1 Is an Autocrine Modulator of Endothelial Angiogenic Responses to Hepatocyte Growth Factor
Published in The Journal of biological chemistry (28-11-2003)“…Stanniocalcin 1 (STC1) is a secreted glycoprotein originally described as a hormone involved in calcium and phosphate homeostasis in bony fishes. We recently…”
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16
An analysis of the decrease in the assayed level of charged bovine estrogen receptor observed at physiological ionic strength
Published in Journal of steroid biochemistry (01-02-1985)“…Lower assayed levels of heifer uterine estrogen receptor (ER) occur at physiologic ionic strength when ER is separated from [3H]estradiol by Dextran-coated…”
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17
Characterization of CMIX, a chicken homeobox gene related to the Xenopus gene mix.1
Published in Mechanisms of development (01-07-1998)“…Members of the TGF β, Wnt and FGF families act in concert to induce and pattern the mesoderm of gastrulating embryos. Downstream effectors for these growth…”
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Cross-species Vascular Endothelial Growth Factor (VEGF)-blocking Antibodies Completely Inhibit the Growth of Human Tumor Xenografts and Measure the Contribution of Stromal VEGF
Published in The Journal of biological chemistry (13-01-2006)“…To fully assess the role of VEGF-A in tumor angiogenesis, antibodies that can block all sources of vascular endothelial growth factor (VEGF) are desired…”
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Tumor-Driven Paracrine Platelet-Derived Growth Factor Receptor α Signaling Is a Key Determinant of Stromal Cell Recruitment in a Model of Human Lung Carcinoma
Published in Clinical cancer research (01-05-2006)“…Activated fibroblasts are thought to play important roles in the progression of many solid tumors, but little is known about the mechanisms responsible for the…”
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Human Endocrine Gland-Derived Vascular Endothelial Growth Factor: Expression Early in Development and in Leydig Cell Tumors Suggests Roles in Normal and Pathological Testis Angiogenesis
Published in The journal of clinical endocrinology and metabolism (01-08-2004)“…Angiogenesis is essential for tumor growth and metastasis. A new human angiogenic mitogen, endocrine gland-derived vascular endothelial growth factor…”
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