Search Results - "Peachey, A R"

The collagen-binding A-domains of integrins alpha(1)beta(1) and alpha(2)beta(1) recognize the same specific amino acid sequence, GFOGER, in native (triple-helical) collagens by Knight, C G, Morton, L F, Peachey, A R, Tuckwell, D S, Farndale, R W, Barnes, M J

“…We have previously assigned an integrin alpha(2)beta(1)-recognition site in collagen I to the sequence, GFOGERGVEGPOGPA (O = Hyp), corresponding to residues…”
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Platelet-reactive sites in collagens type I and type III. Evidence for separate adhesion and aggregatory sites by Morton, L F, Peachey, A R, Barnes, M J

“…The adhesion of human and rabbit platelets to collagens and collagen-derived fragments immobilized on plastic was investigated. Adhesion appeared to be…”
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Collagen-platelet interaction: Gly-Pro-Hyp is uniquely specific for platelet Gp VI and mediates platelet activation by collagen by Knight, C G, Morton, L F, Onley, D J, Peachey, A R, Ichinohe, T, Okuma, M, Farndale, R W, Barnes, M J

“…Peptides consisting of a repeat Gly-Pro-Hyp sequence are potent platelet agonists. The aim of this study was: (1) to examine the specificity of this sequence…”
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Conformation-dependent platelet adhesion to collagen involving integrin α2β1-mediated and other mechanisms : multiple α2β1-recognition sites in collagen type I by MORTON, L. F, PEACHEY, A. R, ZIJENAH, L. S, GOODALL, A. H, HUMPHRIES, M. J, BARNES, M. J

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Conformation-dependent platelet adhesion to collagen involving integrin alpha 2 beta 1-mediated and other mechanisms: multiple alpha 2 beta 1-recognition sites in collagen type I by Morton, L F, Peachey, A R, Zijenah, L S, Goodall, A H, Humphries, M J, Barnes, M J

“…Platelet adhesion has been measured to type-I monomeric collagen, collagen fibres, alpha 1(I) and alpha 2(I) chains and the chain fragments alpha 1(I)CB3,…”
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Integrin Activation State Determines Selectivity for Novel Recognition Sites in Fibrillar Collagens by Siljander, Pia R-M, Hamaia, Samir, Peachey, Anthony R, Slatter, David A, Smethurst, Peter A, Ouwehand, Willem H, Knight, C Graham, Farndale, Richard W

“…Only three recognition motifs, GFOGER, GLOGER, and GASGER, all present in type I collagen, have been identified to date for collagen-binding integrins, such as…”
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The platelet reactivity of synthetic peptides based on the collagen III fragment alpha1(III)CB4. Evidence for an integrin alpha2beta1 recognition site involving residues 522-528 of the alpha1(III) collagen chain by Morton, L F, Peachey, A R, Knight, C G, Farndale, R W, Barnes, M J

“…The platelet-reactive collagen III-derived fragment alpha1(III)CB4 has been synthesized as seven overlapping peptides, each as a homotrimeric triple-helical…”
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Identification in collagen type I of an integrin alpha2 beta1-binding site containing an essential GER sequence by Knight, C G, Morton, L F, Onley, D J, Peachey, A R, Messent, A J, Smethurst, P A, Tuckwell, D S, Farndale, R W, Barnes, M J

“…The collagen type I-derived fragment alpha1(I)CB3 is known to recognize the platelet collagen receptor integrin alpha2beta1 as effectively as the parent…”
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Collagen-platelet interaction : Gly-Pro-Hyp is uniquely specific for platelet Gp VI and mediates platelet activation by collagen: Atherosclerosis and plaque rupture by KNIGHT, C. G, MORTON, L. F, ONLEY, D. J, PEACHEY, A. R, ICHINOHE, T, OKUMA, M, FARNDALE, R. W, BARNES, M. J

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