Search Results - "Peñuelas, Silvia"
-
1
TGF-β Increases Glioma-Initiating Cell Self-Renewal through the Induction of LIF in Human Glioblastoma
Published in Cancer cell (07-04-2009)“…Glioma-initiating cells (GICs) are responsible for the initiation and recurrence of gliomas. Here, we identify a molecular mechanism that regulates the…”
Get full text
Journal Article -
2
High TGFβ-Smad Activity Confers Poor Prognosis in Glioma Patients and Promotes Cell Proliferation Depending on the Methylation of the PDGF-B Gene
Published in Cancer cell (13-02-2007)“…TGFβ acts as a tumor suppressor in normal epithelial cells and early-stage tumors and becomes an oncogenic factor in advanced tumors. The molecular mechanisms…”
Get full text
Journal Article -
3
Epicatechin and a cocoa polyphenolic extract modulate gene expression in human Caco-2 cells
Published in The Journal of nutrition (01-10-2004)“…We performed a functional genomic analysis to study the effect of epicatechin and polyphenolic cocoa extract in the human colon adenocarcinoma cell line…”
Get more information
Journal Article -
4
Modulation of IMPDH2, survivin, topoisomerase I and vimentin increases sensitivity to methotrexate in HT29 human colon cancer cells
Published in The FEBS journal (01-02-2005)“…We determined differentially expressed genes in HT29 human colon cancer cells, both after short treatment with methotrexate (MTX) and after the resistance to…”
Get full text
Journal Article -
5
Atorvastatin reduces CD68, FABP4, and HBP expression in oxLDL-treated human macrophages
Published in Biochemical and biophysical research communications (21-05-2004)“…With the aim of identifying new target genes that could contribute to limit foam cell formation, we analyzed changes in the pattern of gene expression in human…”
Get full text
Journal Article -
6
Nurse-led in Primary Health Care setting: a well-timed and promising organizational innovation
Published in Enfermeria clinica (01-03-2015)“…At present, the severe economic crisis along with the increasing prevalence of chronic diseases is leading to different countries to consider updating their…”
Get more information
Journal Article -
7
High TGFbeta-Smad activity confers poor prognosis in glioma patients and promotes cell proliferation depending on the methylation of the PDGF-B gene
Published in Cancer cell (01-02-2007)“…TGFbeta acts as a tumor suppressor in normal epithelial cells and early-stage tumors and becomes an oncogenic factor in advanced tumors. The molecular…”
Get full text
Journal Article -
8
Sensitization of human erythroleukemia K562 cells resistant to methotrexate by inhibiting IMPDH
Published in Medical science monitor (01-01-2005)“…Methotrexate (MTX) is an inhibitor of dihydrofolate reductase (DHFR), an enzyme involved in nucleotide synthesis, and is widely used in therapy, but its…”
Get more information
Journal Article -
9
The expression of retinoblastoma and Sp1 is increased by low concentrations of cyclin‐dependent kinase inhibitors
Published in European journal of biochemistry (01-12-2003)“…We examined the effect of suboptimal concentrations of cyclin‐dependent kinase inhibitors, which do not interfere with cell proliferation, on retinoblastoma…”
Get full text
Journal Article