Search Results - "Peñalva, Daniel A"
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Elovl4 and Fa2h expression during rat spermatogenesis: a link to the very-long-chain PUFAs typical of germ cell sphingolipids[S]
Published in Journal of lipid research (2018)“…The sphingolipids (SLs) of rodent spermatogenic cells (spermatocytes, spermatids) and spermatozoa contain nonhydroxylated and 2-hydroxylated versions of…”
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Mfn2-dependent fusion pathway of PE-enriched micron-sized vesicles
Published in Proceedings of the National Academy of Sciences - PNAS (23-07-2024)“…Mitofusins (Mfn1 and Mfn2) are the mitochondrial outer-membrane fusion proteins in mammals and belong to the dynamin superfamily of multidomain GTPases. Recent…”
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Cholesterol and desmosterol incorporation into ram sperm membrane before cryopreservation: Effects on membrane biophysical properties and sperm quality
Published in Biochimica et biophysica acta. Biomembranes (01-09-2020)“…Ram sperm are particularly sensitive to freeze-thawing mainly due to their lipid composition, limiting their use in artificial insemination programs. We…”
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Transbilayer asymmetry and sphingomyelin composition modulate the preferential membrane partitioning of the nicotinic acetylcholine receptor in Lo domains
Published in Archives of biochemistry and biophysics (01-02-2016)“…We have previously shown that the intact nicotinic acetylcholine receptor (AChR) lacks preference for Lo domains when reconstituted in a sphingomyelin (SM),…”
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Membrane Restructuring Events during the Enzymatic Generation of Ceramides with Very Long-Chain Polyunsaturated Fatty Acids
Published in Langmuir (10-04-2018)“…In rat sperm heads, sphingomyelin (SM) species that contain very long-chain polyunsaturated fatty acid (V-SM) become ceramides (V-Cer) after inducing in vitro…”
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Surface Behavior of Sphingomyelins with Very Long Chain Polyunsaturated Fatty Acids and Effects of Their Conversion to Ceramides
Published in Langmuir (22-04-2014)“…Molecular species of sphingomyelin (SM) with nonhydroxy (n) and 2-hydroxy (h) very long chain polyunsaturated fatty acids (n- and h-28:4, 30:5, and 32:5)…”
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Lipid Biochemical and Biophysical Changes in Rat Spermatozoa During Isolation and Functional Activation In Vitro1
Published in Biology of reproduction (01-12-2015)“…In spermatozoa isolated from rat epididymis, lipids are differentially modified after in vitro induction of capacitation (Cap) and the acrosomal reaction (AR)…”
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Mitochondrial membrane models built from native lipid extracts: Interfacial and transport properties
Published in Frontiers in molecular biosciences (23-09-2022)“…The mitochondrion is an essential organelle enclosed by two membranes whose functionalities depend on their very specific protein and lipid compositions…”
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Unique thermal behavior of sphingomyelin species with nonhydroxy and 2-hydroxy very-long-chain (C28-C32) PUFAs
Published in Journal of lipid research (01-08-2013)“…In rat germ cells and spermatozoa, sphingomyelin (SM) contains molecular species with nonhydroxy (n) and 2-hydroxy (h) very-long-chain polyunsaturated fatty…”
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Desmosterol Incorporation Into Ram Sperm Membrane Before Cryopreservation Improves in vitro and in vivo Fertility
Published in Frontiers in cell and developmental biology (24-06-2021)“…Pregnancy rates in ewes are markedly low after cervical insemination with frozen-thawed sperm. Sensitivity of ram sperm to freeze-thawing is related to the…”
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Atypical surface behavior of ceramides with nonhydroxy and 2-hydroxy very long-chain (C28–C32) PUFAs
Published in Biochimica et biophysica acta (01-03-2014)“…Unique species of ceramide (Cer) with very-long-chain polyunsaturated fatty acid (VLCPUFA), mainly 28–32 carbon atoms, 4–5 double bonds, in nonhydroxy and…”
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Lipid Biochemical and Biophysical Changes in Rat Spermatozoa During Isolation and Functional Activation In Vitro
Published in Biology of reproduction (01-12-2015)“…In spermatozoa isolated from rat epididymis, lipids are differentially modified after in vitro induction of capacitation (Cap) and the acrosomal reaction (AR)…”
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