Search Results - "Peña, Francisco Ayala"

Tumor-infiltrating immune cell profiles and their change after neoadjuvant chemotherapy predict response and prognosis of breast cancer by García-Martínez, Elena, Gil, Ginés Luengo, Benito, Asunción Chaves, González-Billalabeitia, Enrique, Conesa, María Angeles Vicente, García García, Teresa, García-Garre, Elisa, Vicente, Vicente, Ayala de la Peña, Francisco

“…Tumor microenvironment immunity is associated with breast cancer outcome. A high lymphocytic infiltration has been associated with response to neoadjuvant…”
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Angiogenic role of miR-20a in breast cancer by Luengo-Gil, Gines, Gonzalez-Billalabeitia, Enrique, Perez-Henarejos, Sergio Alejo, Navarro Manzano, Esther, Chaves-Benito, Asuncion, Garcia-Martinez, Elena, Garcia-Garre, Elisa, Vicente, Vicente, Ayala de la Peña, Francisco

“…Angiogenesis is a key process for tumor progression and a target for treatment. However, the regulation of breast cancer angiogenesis and its relevance for…”
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Loss of p53 and Acquisition of Angiogenic MicroRNA Profile Are Insufficient to Facilitate Progression of Bladder Urothelial Carcinoma in Situ to Invasive Carcinoma by Ayala de la Peña, Francisco, Kanasaki, Keizo, Kanasaki, Megumi, Tangirala, Neelima, Maeda, Genta, Kalluri, Raghu

“…Activation of oncogenes or inactivation of tumor suppressors in urothelium is considered critical for development of urothelial cancer. Here we report cloning…”
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Association of Anthracycline‐Related Cardiac Histological Lesions With NADPH Oxidase Functional Polymorphisms by Cascales, Almudena, Pastor‐Quirante, Francisco, Sánchez‐Vega, Beatriz, Luengo‐Gil, Ginés, Corral, Javier, Ortuño‐Pacheco, Guzmán, Vicente, Vicente, Peña, Francisco Ayala

“…Objective. Treatment with anthracyclines may cause cardiac dysfunction, but the sequence of anthracycline‐induced heart lesions has been incompletely…”
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Trial Watch: Immunostimulation with recombinant cytokines for cancer therapy by García-Martínez, Elena, Smith, Melody, Buqué, Aitziber, Aranda, Fernando, Peña, Francisco Ayala de la, Ivars, Alejandra, Cánovas, Manuel Sanchez, Conesa, Ma Angeles Vicente, Fucikova, Jitka, Spisek, Radek, Zitvogel, Laurence, Kroemer, Guido, Galluzzi, Lorenzo

“…Cytokines regulate virtually aspects of innate and adaptive immunity, including the initiation, execution and extinction of tumor-targeting immune responses…”
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Prediction of quality of life in early breast cancer upon completion of adjuvant chemotherapy by Carmona-Bayonas, Alberto, Calderón, Caterina, Hernández, Raquel, Fernández Montes, Ana, Castelo, Beatriz, Ciria-Suarez, Laura, Antoñanzas, Mónica, Rogado, Jacobo, Pacheco-Barcia, Vilma, Asensio Martínez, Elena, Ivars, Alejandra, Ayala de la Peña, Francisco, Jimenez-Fonseca, Paula

“…Quality of life (QoL) is a complex, ordinal endpoint with multiple conditioning factors. A predictive model of QoL after adjuvant chemotherapy can support…”
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Clinical and genetic determinants of anthracycline-induced cardiac iron accumulation by Cascales, Almudena, Sánchez-Vega, Beatriz, Navarro, Noelia, Pastor-Quirante, Francisco, Corral, Javier, Vicente, Vicente, de la Peña, Francisco Ayala

“…Abstract Background The involvement of iron in anthracycline cardiotoxicity is supported by extensive experimental data, and by the preventive efficacy of…”
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Prediction of serious complications in patients with seemingly stable febrile neutropenia: validation of the Clinical Index of Stable Febrile Neutropenia in a prospective cohort of patients from the FINITE study by Carmona-Bayonas, Alberto, Jiménez-Fonseca, Paula, Virizuela Echaburu, Juan, Antonio, Maite, Font, Carme, Biosca, Mercè, Ramchandani, Avinash, Martínez, Jerónimo, Hernando Cubero, Jorge, Espinosa, Javier, Martínez de Castro, Eva, Ghanem, Ismael, Beato, Carmen, Blasco, Ana, Garrido, Marcelo, Bonilla, Yaiza, Mondéjar, Rebeca, Arcusa Lanza, María Ángeles, Aragón Manrique, Isabel, Manzano, Aránzazu, Sevillano, Elena, Castañón, Eduardo, Cardona, Mercé, Gallardo Martín, Elena, Pérez Armillas, Quionia, Sánchez Lasheras, Fernando, Ayala de la Peña, Francisco

“…To validate a prognostic score predicting major complications in patients with solid tumors and seemingly stable episodes of febrile neutropenia (FN). The…”
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Mutational analysis of RAD51C and RAD51D genes in hereditary breast and ovarian cancer families from Murcia (southeastern Spain) by Sánchez-Bermúdez, Ana Isabel, Sarabia-Meseguer, Ma Desamparados, García-Aliaga, Ángeles, Marín-Vera, Miguel, Macías-Cerrolaza, José Antonio, Henaréjos, Pilar Sánchez, Guardiola-Castillo, Verónica, Peña, Francisco Ayala-de la, Alonso-Romero, José Luis, Noguera-Velasco, José Antonio, Ruiz-Espejo, Francisco

“…RAD51C and RAD51D have been defined as susceptibility genes for hereditary breast and ovarian cancer syndrome in several studies. In the present study, a…”
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Mitochondrial DNA drives abscopal responses to radiation that are inhibited by autophagy by Yamazaki, Takahiro, Kirchmair, Alexander, Sato, Ai, Buqué, Aitziber, Rybstein, Marissa, Petroni, Giulia, Bloy, Norma, Finotello, Francesca, Stafford, Lena, Navarro Manzano, Esther, Ayala de la Peña, Francisco, García-Martínez, Elena, Formenti, Silvia C., Trajanoski, Zlatko, Galluzzi, Lorenzo

“…Autophagy supports both cellular and organismal homeostasis. However, whether autophagy should be inhibited or activated for cancer therapy remains unclear…”
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Psychometric properties of Liverpool Stoicism Scale (LSS) in a cohort of patients with resected cancer in adjuvant treatment by Calderon, Caterina, Ferrando, Pere Joan, Lorenzo-Seva, Urbano, Carmona-Bayonas, Alberto, Jara, Carlos, Ayala de la peña, Francisco, Beato, Carmen, Ramchandani, Avinash, Garcia, Teresa, Mangas-Izquierdo, Montserrat, Castelo, Beatriz, Donnay, Olga, Muñoz, Maria Del Mar, Martinez de Castro, Eva, García, Sara, Ghanem, Ismael, Mellen, Teo, Jiménez-Fonseca, Paula

“…Stoicism has been used to describe a wide range of behaviors in the face of disease that go from silence, resistance to the adversity, or ‘to make the best of…”
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A new prognostic model including immune biomarkers, genomic proliferation tumor markers ( AURKA and MYBL2 ) and clinical-pathological features optimizes prognosis in neoadjuvant breast cancer patients by García-Torralba, Esmeralda, Navarro Manzano, Esther, Luengo-Gil, Gines, De la Morena Barrio, Pilar, Chaves Benito, Asunción, Pérez-Ramos, Miguel, Álvarez-Abril, Beatriz, Ivars Rubio, Alejandra, García-Garre, Elisa, Ayala de la Peña, Francisco, García-Martínez, Elena

“…Up to 30% of breast cancer (BC) patients treated with neoadjuvant chemotherapy (NCT) will relapse. Our objective was to analyze the predictive capacity of…”
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Sex differences in the diagnosis, treatment and prognosis of cancer: the rationale for an individualised approach by Vera, Ruth, Juan-Vidal, Oscar, Safont-Aguilera, María José, de la Peña, Francisco Ayala, del Alba, Aránzazu González

“…Background Precision medicine in oncology aims to identify the most beneficial interventions based on a patient’s individual features and disease. However,…”
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Recurrent genetic variants and prioritization of variants of uncertain clinical significance associated with hereditary breast and ovarian cancer in families from the Region of Murcia by Rosado-Jiménez, Laura, Mestre-Terkemani, Younes, García-Aliaga, Ángeles, Marín-Vera, Miguel, Macías-Cerrolaza, José Antonio, Sarabia-Meseguer, María Desamparados, García-Hernández, María Rosario, Zafra-Poves, Marta, Sánchez-Henarejos, Pilar, Ayala de la Peña, Francisco, Alonso-Romero, José Luis, Noguera-Velasco, José Antonio, Ruiz-Espejo, Francisco

“…Hereditary breast and ovarian cancer (HBOC) follows an autosomal dominant inheritance pattern of cancer susceptibility genes. The risk of developing this…”
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Loss of β1‐integrin from urothelium results in overactive bladder and incontinence in mice: a mechanosensory rather than structural phenotype by Kanasaki, Keizo, Yu, Weiqun, Bodungen, Maximilian, Larigakis, John D., Kanasaki, Megumi, Pena, Francisco Ayala, Kalluri, Raghu, Hill, Warren G.

“…Bladder urothelium senses and communicates information about bladder fullness. However, the mechanoreceptors that respond to tissue stretch are poorly defined…”
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Recommendations by the Spanish Society of Hospital Pharmacy, the Spanish Society of Oncology Nursing and the Spanish Society of Medical Oncology for the safe management of antineoplastic medication in cancer patients by Otero, María José, Vera, Ruth, González-Pérez, Cristina, Ayala de la Peña, Francisco, Peñuelas, Ángeles, Quer, Nuria

“…To define recommendations that permit safe management of  antineoplastic medication, minimise medication errors and improve the safety of  cancer patients…”
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Neutrophil-lymphocyte ratio in metastatic breast cancer is not an independent predictor of survival, but depends on other variables by Ivars Rubio, Alejandra, Yufera, Juan Carlos, de la Morena, Pilar, Fernández Sánchez, Ana, Navarro Manzano, Esther, García Garre, Elisa, García Martinez, Elena, Marín Zafra, Gema, Sánchez Cánovas, Manuel, García Torralba, Esmeralda, Ayala de la Peña, Francisco

“…The prognostic impact of neutrophil-lymphocyte ratio (NLR) in metastatic breast cancer (MBC) has been previously evaluated in early and metastatic mixed breast…”
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Clinical and biological impact of miR-18a expression in breast cancer after neoadjuvant chemotherapy by Luengo-Gil, Ginés, García-Martínez, Elena, Chaves-Benito, Asunción, Conesa-Zamora, Pablo, Navarro-Manzano, Esther, González-Billalabeitia, Enrique, García-Garre, Elisa, Martínez-Carrasco, Alberto, Vicente, Vicente, Ayala de la Peña, Francisco

“…Purpose The analysis of breast cancer residual tumors after neoadjuvant chemotherapy (nCT) may be useful for identifying new biomarkers. MicroRNAs are known to…”
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Prognostic and Predictive Effects of Tumor and Plasma miR-200c-3p in Locally Advanced and Metastatic Breast Cancer by Navarro-Manzano, Esther, Luengo-Gil, Ginés, González-Conejero, Rocío, García-Garre, Elisa, García-Martínez, Elena, García-Torralba, Esmeralda, Chaves-Benito, Asunción, Vicente, Vicente, Ayala de la Peña, Francisco

“…While the role of miR-200c in cancer progression has been established, its expression and prognostic role in breast cancer is not completely understood. The…”
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Antithrombin controls tumor migration, invasion and angiogenesis by inhibition of enteropeptidase by Luengo-Gil, Ginés, Calvo, María Inmaculada, Martín-Villar, Ester, Águila, Sonia, Bohdan, Nataliya, Antón, Ana I., Espín, Salvador, Ayala de la Peña, Francisco, Vicente, Vicente, Corral, Javier, Quintanilla, Miguel, Martínez-Martínez, Irene

“…Antithrombin is a key inhibitor of the coagulation cascade, but it may also function as an anti-inflammatory, anti-angiogenic, anti-viral and anti-apoptotic…”
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