Search Results - "Peña, Edsel"

Conversations with Gábor J. Székely by Gel, Yulia R., Peña, Edsel A., Wang, Huixia Judy

“…Gábor J. Székely was born in Budapest, Hungary on February 4, 1947. He graduated from Eötvös Loránd University (ELTE) with an M.S. degree in 1970, and a Ph.D…”
Get full text

Prediction intervals for Poisson‐based regression models by Kim, Taeho, Lieberman, Benjamin, Luta, George, Peña, Edsel A.

“…This paper provides a review of the literature regarding methods for constructing prediction intervals for counting variables, with particular focus on those…”
Get full text

Global Validation of Linear Model Assumptions by Peña, Edsel A, Slate, Elizabeth H

“…An easy-to-implement global procedure for testing the four assumptions of the linear model is proposed. The test can be viewed as a Neyman smooth test and…”
Get full text

Comparison of multistate Markov modeling with contemporary outcomes in a reanalysis of the NINDS tissue plasminogen activator for acute ischemic stroke treatment trial by Cassarly, Christy, Martin, Renee' H, Chimowitz, Marc, Peña, Edsel A, Ramakrishnan, Viswanathan, Palesch, Yuko Y

“…Historically, ordinal measures of functional outcome have been dichotomized for the primary analysis in acute stroke therapy trials. A number of alternative…”
Get full text

Fast serotonin voltammetry as a versatile tool for mapping dynamic tissue architecture: I. Responses at carbon fibers describe local tissue physiology by Abdalla, Aya, West, Alyssa, Jin, Yunju, Saylor, Rachel A., Qiang, Beidi, Peña, Edsel, Linden, David J., Nijhout, H. Frederik, Reed, Michael C., Best, Janet, Hashemi, Parastoo

“…It is important to monitor serotonin neurochemistry in the context of brain disorders. Specifically, a better understanding of biophysical alterations and…”
Get full text

On Optimal Correlation-Based Prediction by Bottai, Matteo, Kim, Taeho, Lieberman, Benjamin, Luta, George, Peña, Edsel

“…This note examines, at the population-level, the approach of obtaining predictors of a random variable Y, given the joint distribution of , by maximizing the…”
Get full text

Sojourning With the Homogeneous Poisson Process by Liu, Piaomu, Peña, Edsel A.

“…In this pedagogical article, distributional properties, some surprising, pertaining to the homogeneous Poisson process (HPP), when observed over a possibly…”
Get full text

POWER-ENHANCED MULTIPLE DECISION FUNCTIONS CONTROLLING FAMILY-WISE ERROR AND FALSE DISCOVERY RATES by Peña, Edsel A., Habiger, Joshua D., Wu, Wensong

“…Improved procedures, in terms of smaller missed discovery rates (MDR), for performing multiple hypotheses testing with weak and strong control of the…”
Get full text

Inhibition of the Dead Box RNA Helicase 3 Prevents HIV-1 Tat and Cocaine-Induced Neurotoxicity by Targeting Microglia Activation by Aksenova, Marina, Sybrandt, Justin, Cui, Biyun, Sikirzhytski, Vitali, Ji, Hao, Odhiambo, Diana, Lucius, Matthew D., Turner, Jill R., Broude, Eugenia, Peña, Edsel, Lizarraga, Sofia, Zhu, Jun, Safro, Ilya, Wyatt, Michael D., Shtutman, Michael

“…HIV-1 Associated Neurocognitive Disorder (HAND) is a common and clinically detrimental complication of HIV infection. Viral proteins, including Tat, released…”
Get full text

Compound p-value statistics for multiple testing procedures by Habiger, Joshua D., Peña, Edsel A.

“…Many multiple testing procedures make use of the p-values from the individual pairs of hypothesis tests, and are valid if the p-value statistics are…”
Get full text

Estimating Load-Sharing Properties in a Dynamic Reliability System by Kvam, Paul H, Peña, Edsel A

“…An estimator for the load-share parameters in an equal load-share model is derived based on observing k-component parallel systems of identical components that…”
Get full text

Treatment effect on ordinal functional outcome using piecewise multistate Markov model with unobservable baseline: an application to the modified Rankin scale by Cassarly, Christy, Martin, Renee' H., Chimowitz, Marc, Peña, Edsel A., Ramakrishnan, Viswanathan, Palesch, Yuko Y.

“…In clinical trials, longitudinally assessed ordinal outcomes are commonly dichotomized and only the final measure is used for primary analysis, partly for ease…”
Get full text

Dynamic Modeling and Statistical Analysis of Event Times by Peña, Edsel A.

“…This review article provides an overview of recent work in the modeling and analysis of recurrent events arising in engineering, reliability, public health,…”
Get full text

Nonparametric estimation with recurrent competing risks data by Taylor, Laura L., Peña, Edsel A.

“…Nonparametric estimators of component and system life distributions are developed and presented for situations where recurrent competing risks data from series…”
Get full text

Parametric latent class joint model for a longitudinal biomarker and recurrent events by Han, Jun, Slate, Elizabeth H., Peña, Edsel A.

“…A joint model for a longitudinal biomarker and recurrent events is proposed. This general model accommodates the effects of covariates on the biomarker and…”
Get full text

Assessing Type I error and power of multistate Markov models for panel data-A simulation study by Cassarly, Christy, Martin, Renee' H., Chimowitz, Marc, Peña, Edsel A., Ramakrishnan, Viswanathan, Palesch, Yuko Y.

“…Ordinal outcomes collected at multiple follow-up visits are common in clinical trials. Sometimes, one visit is chosen for the primary analysis and the scale is…”
Get full text

Estimation and efficiency with recurrent event data under informative monitoring by Adekpedjou, Akim, Peña, Edsel A., Quiton, Jonathan

“…This article deals with studies that monitor occurrences of a recurrent event for n subjects or experimental units. It is assumed that the ith unit is…”
Get full text

The impact of model uncertainty on benchmark dose estimation by West, R. Webster, Piegorsch, Walter W., Peña, Edsel A., An, Lingling, Wu, Wensong, Wickens, Alissa A., Xiong, Hui, Chen, Wenhai

“…We study the popular benchmark dose (BMD) approach for estimation of low exposure levels in toxicological risk assessment, focusing on dose–response…”
Get full text

Semiparametric inference for a general class of models for recurrent events by Peña, Edsel A., Slate, Elizabeth H., González, Juan R.

“…Procedures for estimating the parameters of the general class of semiparametric models for recurrent events proposed by Peña and Hollander [(2004). Models for…”
Get full text

Characterization of the bipartite degron that regulates ubiquitin-independent degradation of thymidylate synthase by Barbour, Karen W, Xing, Yang-Yang, Peña, Edsel A, Berger, Franklin G

“…TS (thymidylate synthase) is a key enzyme in the de novo biosynthesis of dTMP, and is indispensable for DNA replication. Previous studies have shown that…”
Get full text