Search Results - "Paz, Ana C"
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Treatment with a Small Molecule Mutant IDH1 Inhibitor Suppresses Tumorigenic Activity and Decreases Production of the Oncometabolite 2-Hydroxyglutarate in Human Chondrosarcoma Cells
Published in PloS one (14-09-2015)“…Chondrosarcomas are malignant bone tumors that produce cartilaginous matrix. Mutations in isocitrate dehydrogenase enzymes (IDH1/2) were recently described in…”
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Bioengineered three-layered robust and elastic artery using hemodynamically-equivalent pulsatile bioreactor
Published in Circulation (New York, N.Y.) (30-09-2008)“…There is an essential demand for tissue engineered autologous small-diameter vascular graft, which can function in arterial high pressure and flow circulation…”
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Metabolic Enzymes in Sarcomagenesis: Progress Toward Biology and Therapy
Published in BioDrugs : clinical immunotherapeutics, biopharmaceuticals, and gene therapy (01-10-2017)“…Cellular metabolism reprogramming is an emerging hallmark of cancer, which provides tumor cells with not only necessary energy but also crucial materials to…”
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Tools for micropatterning epithelial cells into microcolonies on transwell filter substrates
Published in Lab on a chip (21-10-2011)“…Despite the importance of epithelial tissue in most major organs there have been limited attempts to tissue engineer artificial epithelium. A key feature of…”
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Micropatterning Cells on Permeable Membrane Filters
Published in Methods in Cell Biology (2014)“…Epithelium is abundantly present in the human body as it lines most major organs. Therefore, ensuring the proper function of epithelium is pivotal for…”
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Book Chapter Journal Article -
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Epigenetic regulation of embryonic stem cell marker miR302C in human chondrosarcoma as determinant of antiproliferative activity of proline-rich polypeptide 1
Published in International journal of oncology (01-08-2015)“…Metastatic chondrosarcoma of mesenchymal origin is the second most common bone malignancy and does not respond either to chemotherapy or radiation; therefore,…”
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Challenges and opportunities for tissue-engineering polarized epithelium
Published in Tissue engineering. Part B, Reviews (01-02-2014)“…The epithelium is one of the most important tissue types in the body and the specific organization of the epithelial cells in these tissues is important for…”
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Engineering functional islets from cultured cells
Published in Tissue engineering. Part A (01-11-2009)“…Although pancreatic islet transplantation can now be performed minimally invasively in patients with type 1 diabetes, the availability of functional islet…”
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Micropatterning Co-cultures of Epithelial Cells on Filter Insert Substrates
Published in Journal of epithelial biology & pharmacology (24-01-2012)Get full text
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Treatment with a Small Molecule Mutant IDH1 Inhibitor Suppresses Tumorigenic Activity and Decreases Production of the Oncometabolite 2-Hydroxyglutarate in Human Chondrosarcoma Cells: e0133813
Published in PloS one (01-09-2015)“…Chondrosarcomas are malignant bone tumors that produce cartilaginous matrix. Mutations in isocitrate dehydrogenase enzymes (IDH1/2) were recently described in…”
Get full text
Journal Article