Search Results - "Payton, M. A."

Heightened response of eosinophilic asthmatic patients to the CRTH2 antagonist OC000459 by Pettipher, R., Hunter, M. G., Perkins, C. M., Collins, L. P., Lewis, T., Baillet, M., Steiner, J., Bell, J., Payton, M. A.

“…Background The CRTH2 antagonist OC000459 has previously been demonstrated to reduce airway inflammation and improve lung function in moderate persistent…”
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The CRTH2 antagonist OC000459 reduces nasal and ocular symptoms in allergic subjects exposed to grass pollen, a randomised, placebo-controlled, double-blind trial by Horak, F., Zieglmayer, P., Zieglmayer, R., Lemell, P., Collins, L. P., Hunter, M. G., Steiner, J., Lewis, T., Payton, M. A., Perkins, C. M., Pettipher, R.

“…Background CRTH2 mediates activation of Th2 cells, eosinophils and basophils in response to prostaglandin D2. The CRTH2 antagonist OC000459 has previously been…”
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Expression of arylamine N-acetyltransferases in pre-term placentas and in human pre-implantation embryos by Smelt, V A, Upton, A, Adjaye, J, Payton, M A, Boukouvala, S, Johnson, N, Mardon, H J, Sim, E

“…Arylamine N -acetyltransferases (NATs) catalyse the acetylation from acetyl-CoA of arylamines and hydrazines. There are two human isoenzymes which show…”
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The osmotic integrity of the yeast cell requires a functional PKC1 gene product by PARAVICINI, G, COOPER, M, FRIEDLI, L, SMITH, D. J, CARPENTIER, J.-L, KLIG, L. S, PAYTON, M. A

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Genotyping Human Arylamine N-Acetyltransferase Type 1 (NAT1) : The Identification of Two Novel Allelic Variants by Payton, Mark A, Sim, Edith

“…Human arylamine N-acetyltransferase (NAT) is known to exist as two isoenzymes, NAT1 and NAT2, with different though overlapping substrate specificities. NAT1…”
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Validity of screening for individuals at risk for type I diabetes by combined analysis of antibodies to recombinant proteins by CHRISTIE, M. R, ROLL, U, PAYTON, M. A, HATFIELD, E. C. I, ZIEGLER, A.-G

“…Validity of screening for individuals at risk for type I diabetes by combined analysis of antibodies to recombinant proteins. M R Christie , U Roll , M A…”
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Perinatal autoimmunity in offspring of diabetic parents. The German Multicenter BABY-DIAB study: detection of humoral immune responses to islet antigens in early childhood by Roll, U., Christie, M. R., Fuchtenbusch, M., Payton, M. A., Hawkes, C. J., Ziegler, A. G.

“…Perinatal autoimmunity in offspring of diabetic parents. The German Multicenter BABY-DIAB study: detection of humoral immune responses to islet antigens in…”
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Protein kinase C in yeast: characteristics of the Saccharomyces cerevisiae PKC1 gene product by Antonsson, B, Montessuit, S, Friedii, L, Payton, M.A, Paravicini, G

“…The Saccharomyces cerevisiae PKC1 gene encodes a homolog of mammalian protein kinase C (Levin, D. E., Fields, F. O., Kunisawa, R., Bishop, J. M., and Thorner,…”
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A novel Saccharomyces cerevisiae secretory mutant possesses a thermolabile phosphomannose isomerase by Payton, M.A. (Glaxo Institute for Molecular Biology S.A., Geneva, Switzerland), Rheinnecker, M, Klig, L.S, DeTiani, M, Bowden, E

“…A temperature-sensitive mutant of Saccharomyces cerevisiae was identified which at the restrictive temperature of 37 degrees C is unable to secrete a number of…”
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PMI40, an intron-containing gene required for early steps in yeast mannosylation by SMITH, D. J, PROUDFOOT, A, FRIEDLI, L, KLIG, L. S, PARAVICINI, G, PAYTON, M. A

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Cross reactivity between IA-2 and phogrin/IA-2β in binding of autoantibodies in IDDM by HATFIELD, E. C. I, HAWKES, C. J, PAYTON, M. A, CHRISTIE, M. R

“…SummaryPatients with insulin-dependent diabetes mellitus (IDDM) possess antibodies to the cytoplasmic domains of two closely related tyrosine phosphatase-like…”
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Conversion of Glucose to 2-Keto-l-Gulonate, an Intermediate in l-Ascorbate Synthesis, by a Recombinant Strain of Erwinia citreus by GRINDLEY, J. F, PAYTON, M. A, VAN DE POL, H, HARDY, K. G

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Hyphal tip extension in Aspergillus nidulans requires the manA gene, which encodes phosphomannose isomerase by Smith, D J, Payton, M A

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Characterization of the yeast (1 leads to 6)-beta-glucan biosynthetic components, Kre6p and Skn1p, and genetic interactions between the PKC1 pathway and extracellular matrix assembly by Roemer, T. (McGill University, Montreal, Quebec, Canada), Paravicini, G, Payton, M.A, Bussey, H

“…A characterization of the S. cerevisiae KRE6 and SKN1 gene products extends previous genetic studies on their role in (1 leads to 6)-beta-glucan biosynthesis…”
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Identification of Cys-150 in the active site of phosphomannose isomerase from Candida albicans by Coulin, Florence, Magnenat, Edith, Proudfoot, Amanda E. I, Payton, Mark A, Scully, Paul, Wells, Timothy N. C

“…Candida albicans phosphomannose isomerase (PMI) (EC 5.3.1.8) has been recently cloned and overexpressed in Escherichia coli. The enzyme can be irreversibly…”
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Yeast α-mating factor receptor-linked G-protein signal transduction suppresses Ras-dependent activity by ARKINSTALL, S. J, PAPASAVVAS, S. G, PAYTON, M. A

“…Homologues of mammalian Ras conserved in Saccharomyces cerevisiae mediate glucose-stimulated cyclic AMP formation and we used this response to test for…”
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Purification cDNA cloning and heterologous expression of human phosphomannose isomerase by PROUDFOOT, Amanda E. I., TURCATTI, Gerardo, WELLS, Timothy N. C., PAYTON, Mark A., SMITH, David J.

“…Phosphomannose isomerase catalyses the interconversion of fructose‐6‐P and mannose‐6‐P and has a critical role in the supply of d‐mannose derivatives required…”
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Crystallization and preliminary X-ray analysis of Candida albicans phosphomannose isomerase by Tolley, S, Davies, G, Hubbard, R E, Smith, D J, Proudfoot, A E, Payton, M A, Cleasby, A, Wonacott, A, Wells, T N

“…Crystals of recombinant phosphomannose isomerase from Candida albicans have been obtained in a form suitable for X-ray diffraction analysis. The enzyme plays a…”
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Purification and characterization of 5-ketofructose reductase from Erwinia citreus by Schrimsher, J L, Wingfield, P T, Bernard, A, Mattaliano, R, Payton, M A

“…5-Ketofructose reductase [D(-)fructose:(NADP+) 5-oxidoreductase] was purified to homogeneity from Erwinia citreus and demonstrated to catalyse the reversible…”
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The isolation of osmotic-remedial conditional lethal mutants of Candida albicans by PAYTON, M. A, DE TIANI, M

“…We have developed a method for the isolation of a broad range of conditional lethal mutants of the pathogenic fungus Candida albicans. The method substantially…”
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