Search Results - "Payne, Richard"

Missing enzymes in the biosynthesis of the anticancer drug vinblastine in Madagascar periwinkle by Caputi, Lorenzo, Franke, Jakob, Farrow, Scott C, Chung, Khoa, Payne, Richard M E, Nguyen, Trinh-Don, Dang, Thu-Thuy T, Soares Teto Carqueijeiro, Inês, Koudounas, Konstantinos, Dugé de Bernonville, Thomas, Ameyaw, Belinda, Jones, D Marc, Vieira, Ivo Jose Curcino, Courdavault, Vincent, O'Connor, Sarah E

“…Vinblastine, a potent anticancer drug, is produced by (Madagascar periwinkle) in small quantities, and heterologous reconstitution of vinblastine biosynthesis…”
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Sera Monastery by Payne, Richard

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Electrochemistry for the Chemoselective Modification of Peptides and Proteins by Mackay, Angus S, Payne, Richard J, Malins, Lara R

“…Although electrochemical strategies for small-molecule synthesis are flourishing, this technology has yet to be fully exploited for the mild and…”
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Effects of norethisterone acetate on the performance of female racing Greyhounds by Payne, Richard M.

“…A comparison between the performance of spayed female racing Greyhounds and those suppressed with norethisterone acetate (NTA) was made. Previous work by the…”
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Recent extensions to native chemical ligation for the chemical synthesis of peptides and proteins by Malins, Lara R, Payne, Richard J

“…•Recent progress in ligation chemistry for the synthesis of peptides and proteins is outlined.•Extensions of native chemical ligation at thiol and selenol…”
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Advances in chemical ligation strategies for the synthesis of glycopeptides and glycoproteins by Payne, Richard J, Wong, Chi-Huey

“…A number of recent advances in the chemical synthesis of glycopeptides and glycoproteins are described, with particular focus on the development of peptide…”
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Rapid and efficient protein synthesis through expansion of the native chemical ligation concept by Kulkarni, Sameer S., Sayers, Jessica, Premdjee, Bhavesh, Payne, Richard J.

“…The growing interest in proteins, both in fundamental research and in drug discovery, has fuelled demand for efficient synthetic methods to access these…”
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On the Reproducibility of Psychological Science by Johnson, Valen E., Payne, Richard D., Wang, Tianying, Asher, Alex, Mandal, Soutrik

“…Investigators from a large consortium of scientists recently performed a multi-year study in which they replicated 100 psychology experiments. Although…”
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Peptide nucleic acid-templated selenocystine-selenoester ligation enables rapid miRNA detection by Sayers, Jessica, Payne, Richard J, Winssinger, Nicolas

“…The development of a rapid and chemoselective selenocystine-selenoester peptide ligation that operates at nanomolar reactant concentrations has been developed…”
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Single-cell multi-omics in the medicinal plant Catharanthus roseus by Li, Chenxin, Wood, Joshua C., Vu, Anh Hai, Hamilton, John P., Rodriguez Lopez, Carlos Eduardo, Payne, Richard M. E., Serna Guerrero, Delia Ayled, Gase, Klaus, Yamamoto, Kotaro, Vaillancourt, Brieanne, Caputi, Lorenzo, O’Connor, Sarah E., Robin Buell, C.

“…Advances in omics technologies now permit the generation of highly contiguous genome assemblies, detection of transcripts and metabolites at the level of…”
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Revealing the functional roles of tyrosine sulfation using synthetic sulfopeptides and sulfoproteins by Maxwell, Joshua W.C., Payne, Richard J.

“…The decoration of proteins with post-translational modifications (PTMs) serves as a mechanism to expand the functional repertoire of the proteome. Tyrosine…”
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An NPF transporter exports a central monoterpene indole alkaloid intermediate from the vacuole by Payne, Richard M. E., Xu, Deyang, Foureau, Emilien, Teto Carqueijeiro, Marta Ines Soares, Oudin, Audrey, Bernonville, Thomas Dugé de, Novak, Vlastimil, Burow, Meike, Olsen, Carl-Erik, Jones, D. Marc, Tatsis, Evangelos C., Pendle, Ali, Ann Halkier, Barbara, Geu-Flores, Fernando, Courdavault, Vincent, Nour-Eldin, Hussam Hassan, O'Connor, Sarah E.

“…Plants sequester intermediates of metabolic pathways into different cellular compartments, but the mechanisms by which these molecules are transported remain…”
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Seven Reasons Why Protists Make Useful Bioindicators by Payne, Richard J

“…To introduce the special issue, this article reviews the use of protists as bioindicators. Seven key advantages of protist bioindicators are highlighted,…”
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PROTACs Targeting MLKL Protect Cells from Necroptosis by Rathje, Oliver H., Perryman, Lara, Payne, Richard J., Hamprecht, Dieter W.

“…Mixed Lineage Kinase domain-Like pseudokinase (MLKL) is implicated in a broad range of diseases due to its role as the ultimate effector of necroptosis and has…”
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Synthesis and Utility of β‑Selenophenylalanine and β‑Selenoleucine in Diselenide–Selenoester Ligation by Wang, Xiaoyi, Corcilius, Leo, Premdjee, Bhavesh, Payne, Richard J

“…The synthesis of suitably protected β-selenophenylalanine and β-selenoleucine amino acids was accomplished from Garner’s aldehyde as a common starting point…”
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Peptide Ligation at High Dilution via Reductive Diselenide-Selenoester Ligation by Chisholm, Timothy S, Kulkarni, Sameer S, Hossain, Khondker R, Cornelius, Flemming, Clarke, Ronald J, Payne, Richard J

“…Peptide ligation chemistry has revolutionized protein science by providing access to homogeneously modified peptides and proteins. However, lipidated…”
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A Bayesian survival treed hazards model using latent Gaussian processes by Payne, Richard D, Guha, Nilabja, Mallick, Bani K

“…Survival models are used to analyze time-to-event data in a variety of disciplines. Proportional hazard models provide interpretable parameter estimates, but…”
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Taxonomic and functional turnover are decoupled in European peat bogs by Robroek, Bjorn J. M., Jassey, Vincent E. J., Payne, Richard J., Martí, Magalí, Bragazza, Luca, Bleeker, Albert, Buttler, Alexandre, Caporn, Simon J. M., Dise, Nancy B., Kattge, Jens, Zając, Katarzyna, Svensson, Bo H., van Ruijven, Jasper, Verhoeven, Jos T. A.

“…In peatland ecosystems, plant communities mediate a globally significant carbon store. The effects of global environmental change on plant assemblages are…”
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Chemical Synthesis and Semisynthesis of Lipidated Proteins by Hanna, Cameron C., Kriegesmann, Julia, Dowman, Luke J., Becker, Christian F. W., Payne, Richard J.

“…Lipidation is a ubiquitous modification of peptides and proteins that can occur either co‐ or post‐translationally. An array of different lipid classes can…”
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Native Chemical Ligation–Photodesulfurization in Flow by Chisholm, Timothy S, Clayton, Daniel, Dowman, Luke J, Sayers, Jessica, Payne, Richard J

“…Native chemical ligation (NCL) combined with desulfurization chemistry has revolutionized the way in which large polypeptides and proteins are accessed by…”
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