Search Results - "Payne, Kimberly J"

The Current Genomic and Molecular Landscape of Philadelphia-like Acute Lymphoblastic Leukemia by Shiraz, Parveen, Payne, Kimberly J, Muffly, Lori

“…Philadelphia (Ph)-like acute lymphoblastic leukemia (ALL) is a high-risk B-cell Acute Lymphoblastic Leukemia (B-ALL) characterized by a gene expression profile…”
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Human papillomavirus type 16 E6 induces oxidative stress and DNA damage by Williams, Vonetta M, Filippova, Maria, Filippov, Valery, Payne, Kimberly J, Duerksen-Hughes, Penelope

“…High-risk types of human papillomavirus (HPV) are the causative agents of virtually all cases of cervical cancer and a significant proportion of other…”
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Palmitic acid is a toll-like receptor 4 ligand that induces human dendritic cell secretion of IL-1β by Nicholas, Dequina A, Zhang, Kangling, Hung, Christopher, Glasgow, Shane, Aruni, Aruni Wilson, Unternaehrer, Juli, Payne, Kimberly J, Langridge, William H R, De Leon, Marino

“…Palmitic acid (PA) and other saturated fatty acids are known to stimulate pro-inflammatory responses in human immune cells via Toll-like receptor 4 (TLR4)…”
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Cutting Edge: Hematopoietic Stem Cell Expansion and Common Lymphoid Progenitor Depletion Require Hematopoietic-Derived, Cell-Autonomous TLR4 in a Model of Chronic Endotoxin by Liu, Ailing, Wang, Yujuan, Ding, Ying, Baez, Ineavely, Payne, Kimberly J, Borghesi, Lisa

“…Hematopoietic stem and progenitors cells (HSPCs) are activated through TLR4 in vitro. However, it remains unclear whether in vivo TLR4 sensing by HSPCs occurs…”
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TSLP as a Potential Therapy in the Treatment of CRLF2 B Cell Acute Lymphoblastic Leukemia by Alkashgari, Hossam R, Ruiz-Jimenez, Caleb, Stoian, Cornelia, Coats, Jacqueline S, Baez, Ineavely, Chirshev, Evgeny, Martinez, Shannalee R, Dovat, Sinisa, Francis-Boyle, Olivia L, Casiano, Carlos A, Payne, Kimberly J

“…Cytokine receptor-like factor 2 B-cell acute lymphoblastic leukemia (CRLF2 B-ALL) is a high-risk subtype characterized by CRLF2 overexpression with poor…”
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Transcriptional Regulation of JARID1B/KDM5B Histone Demethylase by Ikaros, Histone Deacetylase 1 (HDAC1), and Casein Kinase 2 (CK2) in B-cell Acute Lymphoblastic Leukemia by Wang, Haijun, Song, Chunhua, Ding, Yali, Pan, Xiaokang, Ge, Zheng, Tan, Bi-Hua, Gowda, Chandrika, Sachdev, Mansi, Muthusami, Sunil, Ouyang, Hongsheng, Lai, Liangxue, Francis, Olivia L., Morris, Christopher L., Abdel-Azim, Hisham, Dorsam, Glenn, Xiang, Meixian, Payne, Kimberly J., Dovat, Sinisa

“…Impaired function of the Ikaros (IKZF1) protein is associated with the development of high-risk B-cell precursor acute lymphoblastic leukemia (B-ALL). The…”
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Application of vitamin D and vitamin D analogs in acute myelogenous leukemia by Cao, Huynh, Xu, Yi, de Necochea-Campion, Rosalia, Baylink, David J, Payne, Kimberly J, Tang, Xiaolei, Ratanatharathorn, Christina, Ji, Yong, Mirshahidi, Saied, Chen, Chien-Shing

“…Acute myeloid leukemia (AML) is characterized by the accumulation of malignant, transformed immature hematopoietic myeloid precursors that have lost their…”
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Efficient generation of integration-free ips cells from human adult peripheral blood using BCL-XL together with Yamanaka factors by Su, Rui-Jun, Baylink, David J, Neises, Amanda, Kiroyan, Jason B, Meng, Xianmei, Payne, Kimberly J, Tschudy-Seney, Benjamin, Duan, Yuyou, Appleby, Nancy, Kearns-Jonker, Mary, Gridley, Daila S, Wang, Jun, Lau, K-H William, Zhang, Xiao-Bing

“…The ability to efficiently generate integration-free induced pluripotent stem cells (iPSCs) from the most readily available source-peripheral blood-has the…”
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Ikaros Stability and Pericentromeric Localization Are Regulated by Protein Phosphatase 1 by Popescu, Marcela, Gurel, Zafer, Ronni, Tapani, Song, Chunhua, Hung, Ka Ying, Payne, Kimberly J., Dovat, Sinisa

“…Ikaros encodes a zinc finger protein that is involved in gene regulation and chromatin remodeling. The majority of Ikaros localizes at pericentromeric…”
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Few single nucleotide variations in exomes of human cord blood induced pluripotent stem cells by Su, Rui-Jun, Yang, Yadong, Neises, Amanda, Payne, Kimberly J, Wang, Jasmin, Viswanathan, Kasthuribai, Wakeland, Edward K, Fang, Xiangdong, Zhang, Xiao-Bing

“…The effect of the cellular reprogramming process per se on mutation load remains unclear. To address this issue, we performed whole exome sequencing analysis…”
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Platelet-Neutrophil Interactions Are Lower in Cord Blood of Premature Newborns by Esiaba, Ijeoma, Angeles, Danilyn M, Milford, Terry-Ann M, Salto, Lorena M, Payne, Kimberly J, Kidder, Melissa Y, Boskovic, Danilo S

“…To quantify platelet-neutrophil interaction by flow cytometry, in newborn cord blood, as a function of gestational age. Little is known about platelet function…”
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A novel xenograft model to study the role of TSLP-induced CRLF2 signals in normal and malignant human B lymphopoiesis by Francis, Olivia L, Milford, Terry-Ann M, Martinez, Shannalee R, Baez, Ineavely, Coats, Jacqueline S, Mayagoitia, Karina, Concepcion, Katherine R, Ginelli, Elizabeth, Beldiman, Cornelia, Benitez, Abigail, Weldon, Abby J, Arogyaswamy, Keshav, Shiraz, Parveen, Fisher, Ross, Morris, Christopher L, Zhang, Xiao-Bing, Filippov, Valeri, Van Handel, Ben, Ge, Zheng, Song, Chunhua, Dovat, Sinisa, Su, Ruijun Jeanna, Payne, Kimberly J

“…Thymic stromal lymphopoietin (TSLP) stimulates in-vitro proliferation of human fetal B-cell precursors. However, its in-vivo role during normal human B…”
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Differences in mouse and human nonmemory B cell pools by Benitez, Abigail, Weldon, Abby J, Tatosyan, Lynnette, Velkuru, Vani, Lee, Steve, Milford, Terry-Ann, Francis, Olivia L, Hsu, Sheri, Nazeri, Kavoos, Casiano, Carlos M, Schneider, Rebekah, Gonzalez, Jennifer, Su, Rui-Jun, Baez, Ineavely, Colburn, Keith, Moldovan, Ioana, Payne, Kimberly J

“…Identifying cross-species similarities and differences in immune development and function is critical for maximizing the translational potential of animal…”
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IL-7 Dependence in Human B Lymphopoiesis Increases during Progression of Ontogeny from Cord Blood to Bone Marrow by Parrish, Yasmin Khan, Baez, Ineavely, Milford, Terry-Ann, Benitez, Abigail, Galloway, Nicholas, Rogerio, Jaqueline Willeman, Sahakian, Eva, Kagoda, Mercy, Huang, Grace, Hao, Qian-Lin, Sevilla, Yazmar, Barsky, Lora W, Zielinska, Ewa, Price, Mary A, Wall, Nathan R, Dovat, Sinisa, Payne, Kimberly J

“…IL-7 is critical for B cell production in adult mice; however, its role in human B lymphopoiesis is controversial. One challenge was the inability to…”
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Recruitment of Ikaros to Pericentromeric Heterochromatin Is Regulated by Phosphorylation by Gurel, Zafer, Ronni, Tapani, Ho, Sam, Kuchar, Jason, Payne, Kimberly J., Turk, Christoph W., Dovat, Sinisa

“…Ikaros encodes a zinc finger protein that is involved in heritable gene silencing. In hematopoietic cells, Ikaros localizes to pericentromeric heterochromatin…”
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Rapid and efficient reprogramming of human fetal and adult blood CD34~ cells into mesenchymal stem cells with a single factor by Meng, Xianmei, Su, Rui-Jun, Baylink, David J, Neises, Amanda, Kiroyan, Jason B, Lee, Wayne Yuk-Wai, Payne, Kimberly J, Gridley, Daila S, Wang, Jun, Lau, K-H William, Li, Gang, Zhang, Xiao-Bing

“…The direct conversion of skin cells into somatic stem cells has opened new therapeutic possibilities in regenerative medicine. Here, we show that human induced…”
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Human Ikaros Function in Activated T Cells Is Regulated by Coordinated Expression of Its Largest Isoforms by Ronni, Tapani, Payne, Kimberly J., Ho, Sam, Bradley, Michelle N., Dorsam, Glenn, Dovat, Sinisa

“…The Ikaros gene is alternately spliced to generate multiple zinc finger proteins involved in gene regulation and chromatin remodeling. Whereas murine studies…”
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Identification of a novel, human multilymphoid progenitor in cord blood by Hao, Qian-Lin, Zhu, Judy, Price, Mary A., Payne, Kimberly J., Barsky, Lora W., Crooks, Gay M.

“…The earliest stages of lymphoid commitment from human pluripotent hematopoietic stem cells have not been defined. A clonogenic subpopulation of CD34+CD38− cord…”
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STAT5 alters the state of transcriptional networks, driving aggressive leukemia by Dovat, Sinisa, Payne, Kimberly J

“…The transcription factor STAT5 acts as an oncoprotein in B cell acute lymphoblastic leukemia, competing with the transcription factors NF-κB and Ikaros for…”
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Residency and Activation of Myeloid Cells During Remodeling of the Prepartum Murine Cervix1 by Payne, Kimberly J, Clyde, Lindsey A, Weldon, Abby J, Milford, Terry-Ann, Yellon, Steven M

“…Remodeling of the cervix is a critical early component of parturition and resembles an inflammatory process. Infiltration and activation of myeloid immune…”
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