Search Results - "Payne, Kathryn J"
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Lymphoid stromal cells - potential implications for the pathogenesis of CVID
Published in Frontiers in immunology (17-02-2023)“…Non-hematopoietic lymphoid stromal cells (LSC) maintain lymph node architecture and form niches allowing the migration, activation, and survival of immune…”
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Deciphering imprints of impaired memory B-cell maturation in germinal centers of three patients with common variable immunodeficiency
Published in Frontiers in immunology (06-10-2022)“…Common variable immunodeficiency (CVID), characterized by recurrent infections, low serum class-switched immunoglobulin isotypes, and poor antigen-specific…”
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The Antigen Presenting Potential of CD21low B Cells
Published in Frontiers in immunology (21-10-2020)“…Human CD21 low B cells are expanded in autoimmune (AI) diseases and display a unique phenotype with high expression of co-stimulatory molecules, compatible…”
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STAT3 gain-of-function mutations connect leukemia with autoimmune disease by pathological NKG2Dhi CD8+ T cell dysregulation and accumulation
Published in Immunity (Cambridge, Mass.) (13-12-2022)“…The association between cancer and autoimmune disease is unexplained, exemplified by T cell large granular lymphocytic leukemia (T-LGL) where gain-of-function…”
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Human T-bet governs the generation of a distinct subset of CD11c high CD21 low B cells
Published in Science immunology (22-07-2022)“…High-level expression of the transcription factor T-bet characterizes a phenotypically distinct murine B cell population known as "age-associated B cells"…”
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The expansion of human T-bet high CD21 low B cells is T cell dependent
Published in Science immunology (29-10-2021)“…Accumulation of human CD21 B cells in peripheral blood is a hallmark of chronic activation of the adaptive immune system in certain infections and autoimmune…”
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The Antigen Presenting Potential of CD21 low B Cells
Published in Frontiers in immunology (2020)“…Human CD21 B cells are expanded in autoimmune (AI) diseases and display a unique phenotype with high expression of co-stimulatory molecules, compatible with a…”
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Journal Article -
8
STAT3 gain-of-function mutations connect leukemia with autoimmune disease by pathological NKG2D hi CD8 + T cell dysregulation and accumulation
Published in Immunity (Cambridge, Mass.) (13-12-2022)“…The association between cancer and autoimmune disease is unexplained, exemplified by T cell large granular lymphocytic leukemia (T-LGL) where gain-of-function…”
Get full text
Journal Article