Search Results - "Payne, Anthony J."
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Loss of ZnT8 function protects against diabetes by enhanced insulin secretion
Published in Nature genetics (01-11-2019)“…A rare loss-of-function allele p.Arg138* in SLC30A8 encoding the zinc transporter 8 (ZnT8), which is enriched in Western Finland, protects against type 2…”
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Experimental protocol for sea level projections from ISMIP6 stand-alone ice sheet models
Published in The cryosphere (23-07-2020)“…Projection of the contribution of ice sheets to sea level change as part of the Coupled Model Intercomparison Project Phase 6 (CMIP6) takes the form of…”
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Theoretical insights into the methane catalytic decomposition on graphene nanoribbons edges
Published in Frontiers in chemistry (01-06-2023)“…Catalytic methane decomposition (CMD) is receiving much attention as a promising application for hydrogen production. Due to the high energy required for…”
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Impact of model physics on estimating the surface mass balance of the Greenland ice sheet
Published in Geophysical research letters (01-09-2007)“…Long‐term predictions of sea level rise from increased Greenland ice sheet melting have been derived using Positive Degree Day models only. It is, however,…”
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Fine-mapping type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome maps
Published in Nature genetics (01-11-2018)“…We expanded GWAS discovery for type 2 diabetes (T2D) by combining data from 898,130 European-descent individuals (9% cases), after imputation to high-density…”
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Regional transport, source apportionment and health impact of PM10 bound polycyclic aromatic hydrocarbons in Singapore's atmosphere
Published in Environmental pollution (1987) (01-10-2017)“…A study of 16 United States Environmental Protection Agency (USEPA) priority listed PAHs associated with particulate matter ≤ 10 μm (PM10) was conducted in…”
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Type 2 diabetes risk alleles in PAM impact insulin release from human pancreatic β-cells
Published in Nature genetics (01-08-2018)“…The molecular mechanisms underpinning susceptibility loci for type 2 diabetes (T2D) remain poorly understood. Coding variants in peptidylglycine α-amidating…”
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Mass balance of the Greenland and Antarctic ice sheets from 1992 to 2020
Published in Earth system science data (20-04-2023)“…Ice losses from the Greenland and Antarctic ice sheets have accelerated since the 1990s, accounting for a significant increase in the global mean sea level…”
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initMIP-Antarctica: an Ice Sheet Model Initialization Experiment of ISMIP6
Published in The cryosphere (14-05-2019)“…Ice sheet numerical modeling is an important tool to estimate the dynamic contribution of the Antarctic ice sheet to sea level rise over the coming centuries…”
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Recent Progress in Understanding and Projecting Regional and Global Mean Sea Level Change
Published in Current climate change reports (01-12-2015)“…Considerable progress has been made in understanding the present and future regional and global sea level in the 2 years since the publication of the Fifth…”
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Exploring the phenotypic consequences of tissue specific gene expression variation inferred from GWAS summary statistics
Published in Nature communications (08-05-2018)“…Scalable, integrative methods to understand mechanisms that link genetic variants with phenotypes are needed. Here we derive a mathematical expression to…”
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Improving genetic diagnosis in Mendelian disease with transcriptome sequencing
Published in Science translational medicine (19-04-2017)“…Exome and whole-genome sequencing are becoming increasingly routine approaches in Mendelian disease diagnosis. Despite their success, the current diagnostic…”
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Discovery and Fine-Mapping of Type 2 Diabetes Susceptibility Loci in Diverse Populations Using More than a Million Individuals
Published in Diabetes (New York, N.Y.) (01-07-2018)“…To discover type 2 diabetes (T2D) loci and enhance fine-mapping resolution, we conducted the largest meta-analysis of genome-wide association studies of the…”
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Exome sequencing of 20,791 cases of type 2 diabetes and 24,440 controls
Published in Nature (London) (01-06-2019)“…Protein-coding genetic variants that strongly affect disease risk can yield relevant clues to disease pathogenesis. Here we report exome-sequencing analyses of…”
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Regional transport, source apportionment and health impact of PM 10 bound polycyclic aromatic hydrocarbons in Singapore's atmosphere
Published in Environmental pollution (1987) (01-10-2017)“…A study of 16 United States Environmental Protection Agency (USEPA) priority listed PAHs associated with particulate matter ≤ 10 μm (PM ) was conducted in…”
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The Fiji effect: A review of trends in South Pacific politics
Published in Round table (London) (01-10-1989)“…Compares the political situations in PNG, Vanuatu and Fiji. Assesses whether the coups in Fiji will act as a catalyst to destabilise the other Pacific states…”
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University students and politics in Jamaica
Published in Round table (London) (01-04-1989)“…THE ARTICLE FOCUSES ON A CONFLICT BETWEEN UNIVERSITY STUDENTS AND THE GOVERNMENT OF JAMAICA OVER FUNDING OF HIGHER EDUCATION IN THE CARIBBEAN ISLAND. THE…”
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Orthodox liberal development in Jamaica: Theory and practice
Published in Third world quarterly (01-07-1988)“…Seaga's economic policies…”
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Ice Flow Direction Change in Interior West Antarctica
Published in Science (American Association for the Advancement of Science) (24-09-2004)“…Upstream of Byrd Station (West Antarctica), ice-penetrating radar data reveal a distinctive fold structure within the ice, in which isochronous layers are…”
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The Belize Triangle: Relations with Britain, Guatemala and the United States
Published in Journal of inter-American studies and world affairs (01-04-1990)“…Within the international politics of the Caribbean Basin attention is only rarely paid to the position of Belize. This neglect is the more remarkable since…”
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