Search Results - "Payne, A H"

Regulation of expression of steroidogenic enzymes in Leydig cells by PAYNE, A. H, YOUNGBLOOD, G. L

“…The Leydig cell of the testis is the only cell in the male that has the capacity to synthesize testosterone from cholesterol. Testosterone is critical during…”
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Ontogeny of expression of the genes for steroidogenic enzymes P450 side-chain cleavage, 3 beta-hydroxysteroid dehydrogenase, P450 17 alpha-hydroxylase/C17-20 lyase, and P450 aromatase in fetal mouse gonads by Greco, T L, Payne, A H

“…It is well known that fetal androgens are required for male sexual differentiation, and it is thought that fetal ovaries are not steroidogenically active…”
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Trends in testicular carcinoma in England and Wales, 1971–99 by Power, D.A., Brown, R.S.D., Brock, C.S., Payne, H.A., Majeed, A., Babb, P.

“…Objectives To examine incidence, mortality and survival trends in England and Wales for testicular cancer, using the recently developed national cancer and…”
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Hormonal regulation of cytochrome P450 enzymes, cholesterol side-chain cleavage and 17 alpha-hydroxylase/C17-20 lyase in Leydig cells by PAYNE, A. H

“…Testosterone biosynthesis in Leydig cells is dependent on two cytochrome P450 enzymes, cholesterol side-chain cleavage (P450scc) and 17…”
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Müllerian-inhibiting substance regulates androgen synthesis at the transcriptional level by Teixeira, J, Fynn-Thompson, E, Payne, A H, Donahoe, P K

“…Müllerian-inhibiting substance (MIS) is a hormone produced by Sertoli cells of the fetal testes that causes regression of the Müllerian ducts, the precursors…”
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Current trends in colorectal cancer: site, incidence, mortality and survival in England and Wales by Hayne, D, Brown, R S, McCormack, M, Quinn, M J, Payne, H A, Babb, P

“…The objective was to examine trends in colorectal cancer (CRC) incidence and mortality in England and Wales over the last 30 years. Age-standardized incidence,…”
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Penile preservation in squamous cell carcinoma of the bulbomembranous urethra by Christopher, N., Arya, M., Brown, R.S.D., Payne, H.A., Woodhouse, C.R.J., Ralph, D.J.

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Testosterone inhibits cAMP-induced de Novo synthesis of Leydig cell cytochrome P-450(17 alpha) by an androgen receptor-mediated mechanism by Hales, D B, Sha, L L, Payne, A H

“…The regulation of the novo synthesis of the microsomal cytochrome P-450 enzyme, P-450(17 alpha), was studied in mouse Leydig cell cultures. Chronic treatment…”
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Discussion of "Combining Health Data Uses to Ignite Health System Learning" by Denaxas, S, Friedman, C P, Geissbuhler, A, Hemingway, H, Kalra, D, Kimura, M, Kuhn, K A, Payne, T H, Payne, H A, de Quiros, F G B, Wyatt, J C

“…This article is part of a For-Discussion-Section of Methods of Information in Medicine about the paper "Combining Health Data Uses to Ignite Health System…”
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The multiple murine 3β-hydroxysteroid dehydrogenase isoforms: Structure, function, and tissue- and developmentally specific expression by Payne, Anita H., Abbaszade, Ilgar G., Clarke, Trent R., Bain, Paul A., Park, Chang-Hyun J.

“…The enzyme 3β-hydroxysteroid dehydrogenase (3β-HSD) is essential for the biosynthesis of all active steroid hormones. To date five distinct isoforms have been…”
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Neuroendocrine differentiation in prostate cancer: is it detectable and treatable? by Birtle, A.J., Freeman, A., Payne, H.A., Masters, J.R.W., Harland, S.J.

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Steroid product-induced, oxygen-mediated damage of microsomal cytochrome P-450 enzymes in Leydig cell cultures. Relationship to desensitization by Quinn, P G, Payne, A H

“…Treatment of Leydig cells with 1 mM 8-Br-cAMP for 48 h decreased microsomal cytochrome P-450 activities, 17 alpha-hydroxylase and C17-20 lyase, by 60-75% and…”
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Symptomatic hypercalcaemia in paediatric tuberculosis by Payne, H A, Menson, E, Sharland, M, Bryant, P A

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Hormonal regulation of steroidogenic enzyme gene expression in Leydig cells by Payne, A H, Youngblood, G L, Sha, L, Burgos-Trinidad, M, Hammond, S H

“…In normal mouse Leydig cells, steady state levels of mRNA of CYP11A, 3β-hydroxysteroid dehydrogenase Δ⁵- >Δ⁴-isomerase (3βHSD), and CYP17 are differentially…”
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Thermally Assisted Infrared Multiphoton Photodissociation in a Quadrupole Ion Trap by Payne, Anne H, Glish, Gary L

“…Thermally assisted infrared multiphoton photodissociation (TA-IRMPD) provides an effective means to dissociate ions in the quadrupole ion trap mass…”
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The comparative values of bone marrow aspirate and trephine for obtaining bone scan-targeted metastases from hormone-refractory prostate cancer by Brown, R S D, Dogan, A, Ell, P J, Payne, H A, Masters, J R W, Harland, S J

“…Samples of metastatic prostate cancer to bone are difficult to obtain. The aim of this study was to compare the results of bone marrow aspirate and trephine…”
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Steroid synthesis-dependent, oxygen-mediated damage of mitochondrial and microsomal cytochrome P-450 enzymes in rat Leydig cell cultures by Georgiou, M, Perkins, L M, Payne, A H

“…Treatment of primary cultures of rat Leydig cells with 1 mM 8-bromo-cAMP for 2 days at ambient oxygen tension (19%) caused a 59% decrease in mitochondrial…”
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Expression of steroidogenic genes in maternal and extraembryonic cells during early pregnancy in mice by Arensburg, J, Payne, A H, Orly, J

“…The ontogeny and functional role of steroidogenesis during early gestation in rodents is poorly understood. In previous studies, we have shown that expression…”
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Luteinizing hormone and cyclic AMP-mediated induction of microsomal cytochrome P-450 enzymes in cultured mouse Leydig cells by MALASKA, T, PAYNE, A. H

“…Treatment of mouse Leydig cell cultures with luteinizing hormone (LH) or with 8-bromo-cAMP (8-Br-cAMP) for 5 days elicited a dose- and time-dependent increase…”
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The murine 3β-hydroxysteroid dehydrogenase multigene family: Structure, function and tissue-specific expression by Payne, Anita H., Clarke, Trent R., Bain, Paul A.

“…The classical form of the enzyme 5-ene-3β-hydroxysteroid dehydrogenase/isomerase (3βHSD), expressed in adrenal glands and gonads, catalyzes the conversion of…”
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