Search Results - "Pawlak, Verena"

Three-photon head-mounted microscope for imaging deep cortical layers in freely moving rats by Klioutchnikov, Alexandr, Wallace, Damian J., Frosz, Michael H., Zeltner, Richard, Sawinski, Juergen, Pawlak, Verena, Voit, Kay-Michael, Russell, Philip St. J., Kerr, Jason N. D.

“…We designed a head-mounted three-photon microscope for imaging deep cortical layer neuronal activity in a freely moving rat. Delivery of high-energy excitation…”
Get full text

Impact of visual callosal pathway is dependent upon ipsilateral thalamus by Ramachandra, Vishnudev, Pawlak, Verena, Wallace, Damian J., Kerr, Jason N. D.

“…The visual callosal pathway, which reciprocally connects the primary visual cortices, is thought to play a pivotal role in cortical binocular processing. In…”
Get full text

Dopamine Receptor Activation Is Required for Corticostriatal Spike-Timing-Dependent Plasticity by Pawlak, Verena, Kerr, Jason N. D

“…Single action potentials (APs) backpropagate into the higher-order dendrites of striatal spiny projection neurons during cortically driven "up" states. The…”
Get full text

Timing is not Everything: Neuromodulation Opens the STDP Gate by Pawlak, Verena, Wickens, Jeffery R, Kirkwood, Alfredo, Kerr, Jason N D

“…Spike timing dependent plasticity (STDP) is a temporally specific extension of Hebbian associative plasticity that has tied together the timing of presynaptic…”
Get full text

Lack of NMDA Receptor Subtype Selectivity for Hippocampal Long-Term Potentiation by Berberich, Sven, Punnakkal, Pradeep, Jensen, Vidar, Pawlak, Verena, Seeburg, Peter H, Hvalby, Oivind, Kohr, Georg

“…NMDA receptor (NMDAR) 2A (NR2A)- and NR2B-type NMDARs coexist in synapses of CA1 pyramidal cells. Recent studies using pharmacological blockade of NMDAR…”
Get full text

Voltage-independent GluN2A-type NMDA receptor Ca2+ signaling promotes audiogenic seizures, attentional and cognitive deficits in mice by Bertocchi, Ilaria, Eltokhi, Ahmed, Rozov, Andrey, Chi, Vivan Nguyễn, Jensen, Vidar, Bus, Thorsten, Pawlak, Verena, Serafino, Marta, Sonntag, Hannah, Yang, Boyi, Burnashev, Nail, Li, Shi-Bin, Obenhaus, Horst A., Both, Martin, Niewoehner, Burkhard, Single, Frank N., Briese, Michael, Boerner, Thomas, Gass, Peter, Rawlins, John Nick P., Köhr, Georg, Bannerman, David M., Sprengel, Rolf

“…The NMDA receptor-mediated Ca 2+  signaling during simultaneous pre- and postsynaptic activity is critically involved in synaptic plasticity and thus has a key…”
Get full text

Excitotoxicity in vitro by NR2A- and NR2B-containing NMDA receptors by von Engelhardt, Jakob, Coserea, Irinel, Pawlak, Verena, Fuchs, Elke C., Köhr, Georg, Seeburg, Peter H., Monyer, Hannah

“…Excitotoxicity, exacerbating acute brain damage from brain trauma or stroke, is mediated in part by excessive Ca 2+-influx from prolonged NMDA receptor…”
Get full text

Changing the responses of cortical neurons from sub- to suprathreshold using single spikes in vivo by Pawlak, Verena, Greenberg, David S, Sprekeler, Henning, Gerstner, Wulfram, Kerr, Jason N D

“…Action Potential (APs) patterns of sensory cortex neurons encode a variety of stimulus features, but how can a neuron change the feature to which it responds?…”
Get full text

Author Correction: Voltage-independent GluN2A-type NMDA receptor Ca2+ signaling promotes audiogenic seizures, attentional and cognitive deficits in mice by Bertocchi, Ilaria, Eltokhi, Ahmed, Rozov, Andrey, Chi, Vivan Nguyễn, Jensen, Vidar, Bus, Thorsten, Pawlak, Verena, Serafino, Marta, Sonntag, Hannah, Yang, Boyi, Burnashev, Nail, Li, Shi-Bin, Obenhaus, Horst A., Both, Martin, Niewoehner, Burkhard, Single, Frank N., Briese, Michael, Boerner, Thomas, Gass, Peter, Rawlins, John Nick P., Köhr, Georg, Bannerman, David M., Sprengel, Rolf

“…A Correction to this paper has been published: https://doi.org/10.1038/s42003-021-01717-x…”
Get full text

NMDA receptor activation and respiratory chain complex V inhibition contribute to neurodegeneration in d-2-hydroxyglutaric aciduria by Kölker, Stefan, Pawlak, Verena, Ahlemeyer, Barbara, Okun, Jürgen G., Hörster, Friederike, Mayatepek, Ertan, Krieglstein, Josef, Hoffmann, Georg F., Köhr, Georg

“…The inherited neurometabolic disease d‐2‐hydroxyglutaric aciduria is complicated by progressive neurodegeneration of vulnerable brain regions during infancy…”
Get full text

Impaired synaptic scaling in mouse hippocampal neurones expressing NMDA receptors with reduced calcium permeability by Pawlak, Verena, Schupp, Bettina J., Single, Frank N., Seeburg, Peter H., Köhr, Georg

“…NMDA receptors (NMDARs) play a crucial role for the acquisition of functional AMPARs during Hebbian synaptic plasticity at cortical and hippocampal synapses…”
Get full text

Connectomic analysis of thalamus-driven disinhibition in cortical layer 4 by Hua, Yunfeng, Loomba, Sahil, Pawlak, Verena, Voit, Kay-Michael, Laserstein, Philip, Boergens, Kevin M., Wallace, Damian J., Kerr, Jason N.D., Helmstaedter, Moritz

“…Sensory signals are transmitted via the thalamus primarily to layer 4 (L4) of the primary sensory cortices. While information about average neuronal…”
Get full text

Development of sandwich ELISA for detection and quantification of human and murine a disintegrin and metalloproteinase17 by Trad, Ahmad, Hedemann, Nina, Shomali, Mohammad, Pawlak, Verena, Grötzinger, Joachim, Lorenzen, Inken

“…ADAM17 (a disintegrin and metalloproteinase-containing protein 17) is a membrane-bound metalloproteinase, implicates in many physiological processes, including…”
Get full text

Author Correction: Voltage-independent GluN2A-type NMDA receptor Ca 2+ signaling promotes audiogenic seizures, attentional and cognitive deficits in mice by Bertocchi, Ilaria, Eltokhi, Ahmed, Rozov, Andrey, Chi, Vivan Nguyễn, Jensen, Vidar, Bus, Thorsten, Pawlak, Verena, Serafino, Marta, Sonntag, Hannah, Yang, Boyi, Burnashev, Nail, Li, Shi-Bin, Obenhaus, Horst A, Both, Martin, Niewoehner, Burkhard, Single, Frank N, Briese, Michael, Boerner, Thomas, Gass, Peter, Rawlins, John Nick P, Köhr, Georg, Bannerman, David M, Sprengel, Rolf

Get full text

Voltage-independent GluN2A-type NMDA receptor Ca 2+ signaling promotes audiogenic seizures, attentional and cognitive deficits in mice by Bertocchi, Ilaria, Eltokhi, Ahmed, Rozov, Andrey, Chi, Vivan Nguyễn, Jensen, Vidar, Bus, Thorsten, Pawlak, Verena, Serafino, Marta, Sonntag, Hannah, Yang, Boyi, Burnashev, Nail, Li, Shi-Bin, Obenhaus, Horst A, Both, Martin, Niewoehner, Burkhard, Single, Frank N, Briese, Michael, Boerner, Thomas, Gass, Peter, Rawlins, John Nick P, Köhr, Georg, Bannerman, David M, Sprengel, Rolf

“…The NMDA receptor-mediated Ca  signaling during simultaneous pre- and postsynaptic activity is critically involved in synaptic plasticity and thus has a key…”
Get full text

Actin/alpha-actinin-dependent transport of AMPA receptors in dendritic spines: role of the PDZ-LIM protein RIL by Schulz, Torsten W, Nakagawa, Terunaga, Licznerski, Pawel, Pawlak, Verena, Kolleker, Alexander, Rozov, Andrei, Kim, Jinhyun, Dittgen, Tanjew, Köhr, Georg, Sheng, Morgan, Seeburg, Peter H, Osten, Pavel

“…The efficacy of excitatory transmission in the brain depends to a large extent on synaptic AMPA receptors, hence the importance of understanding the delivery…”
Get full text

Sindbis vector SINrep(nsP2S 726): a tool for rapid heterologous expression with attenuated cytotoxicity in neurons by Kim, Jinhyun, Dittgen, Tanjew, Nimmerjahn, Axel, Waters, Jack, Pawlak, Verena, Helmchen, Fritjof, Schlesinger, Sondra, Seeburg, Peter H., Osten, Pavel

“…Sindbis virus-based vectors have been successfully used for transient heterologous protein expression in neurons. Their main limitation arises from…”
Get full text

Ca(2+) and Na(+) dependence of 3-hydroxyglutarate-induced excitotoxicity in primary neuronal cultures from chick embryo telencephalons by Kölker, Stefan, Köhr, Georg, Ahlemeyer, Barbara, Okun, Jürgen G, Pawlak, Verena, Hörster, Friederike, Mayatepek, Ertan, Krieglstein, Josef, Hoffmann, Georg F

“…Glutaryl-CoA dehydrogenase deficiency (also known as glutaric aciduria type I) is an autosomal, recessively inherited neurometabolic disorder with a distinct…”
Get full text

Frequency-dependent impairment of hippocampal LTP from NMDA receptors with reduced calcium permeability by Pawlak, Verena, Jensen, Vidar, Schupp, Bettina J., Kvello, Ane, Hvalby, Øivind, Seeburg, Peter H., Köhr, Georg

“…Changes in postsynaptic Ca2+ levels are essential for alterations in synaptic strength. At hippocampal CA3‐to‐CA1 synapses, the Ca2+ elevations required for…”
Get full text

Ca2+ and Na+ dependence of 3-hydroxyglutarate-induced excitotoxicity in primary neuronal cultures from chick embryo telencephalons by KÖLKER, Stefan, KÖHR, Georg, AHLEMEYER, Barbara, OKUN, Jürgen G, PAWLAK, Verena, HÖRSTER, Friederike, MAYATEPEK, Ertan, KRIEGLSTEIN, Josef, HOFFMANN, Georg F

Get full text