Search Results - "Pawellek, Ruben"

Charged aerosol detector response modeling for fatty acids based on experimental settings and molecular features: a machine learning approach by Pawellek, Ruben, Krmar, Jovana, Leistner, Adrian, Djajić, Nevena, Otašević, Biljana, Protić, Ana, Holzgrabe, Ulrike

“…The charged aerosol detector (CAD) is the latest representative of aerosol-based detectors that generate a response independent of the analytes’ chemical…”
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Performance of ion pairing chromatography and hydrophilic interaction liquid chromatography coupled to charged aerosol detection for the analysis of underivatized amino acids by Pawellek, Ruben, Holzgrabe, Ulrike

“…•Comparison of the influence of IPC and HILIC on CAD performance by RSM.•Significantly higher CAD response and S/N for the HILIC conditions.•Development of…”
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Influence of the mobile phase composition on hyphenated ultraviolet and charged aerosol detection for the impurity profiling of vigabatrin by Pawellek, Ruben, Holzgrabe, Ulrike

“…•Influence of the mobile phase composition on CAD’s noise was investigated by RSM.•Chain length of the applied ion-pairing reagent was the most influential…”
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Power function setting in charged aerosol detection for the linearization of detector response – optimization strategies and their application by Pawellek, Ruben, Muellner, Tibor, Gamache, Paul, Holzgrabe, Ulrike

“…•Power function setting of Charged Aerosol Detector is optimized to linearize signal•Empirical vs. mathematical power function value (PFV) optimization…”
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Impurity profiling of l-aspartic acid and glycine using high-performance liquid chromatography coupled with charged aerosol and ultraviolet detection by Pawellek, Ruben, Schilling, Klaus, Holzgrabe, Ulrike

“…•2 separate HPLC methods for the impurity analysis of l-aspartic acid and glycine.•Charged aerosol and UV detectors were coupled to extend the detection…”
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Influence of charged aerosol detector instrument settings on the ultra-high-performance liquid chromatography analysis of fatty acids in polysorbate 80 by Schilling, Klaus, Pawellek, Ruben, Lovejoy, Katherine, Muellner, Tibor, Holzgrabe, Ulrike

“…•UHPLC method optimization with improved LOQs and significant time and eluent saving.•CAD parameters’ impact on detection limits and linearity was…”
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Quantitative structure-property relationship modeling of polar analytes lacking UV chromophores to charged aerosol detector response by Schilling, Klaus, Krmar, Jovana, Maljurić, Nevena, Pawellek, Ruben, Protić, Ana, Holzgrabe, Ulrike

“…In this study, a quantitative structure-property relationship model was built in order to link molecular descriptors and chromatographic parameters as inputs…”
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