Search Results - "Pawelec, G"
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Immunology of Aging: the Birth of Inflammaging
Published in Clinical reviews in allergy & immunology (01-04-2023)“…The inflammaging concept was introduced in 2000 by Prof. Franceschi. This was an evolutionary or rather a revolutionary conceptualization of the immune changes…”
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Human T cell aging and the impact of persistent viral infections
Published in Frontiers in immunology (13-09-2013)“…Aging is associated with a dysregulation of the immune response, loosely termed "immunosenescence." Each part of the immune system is influenced to some extent…”
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3
Primary epithelial salivary gland tumours in children and adolescents
Published in International journal of oral and maxillofacial surgery (01-01-2018)“…Primary epithelial tumours of the salivary glands are very rare in paediatric patients. The aim of this study was to evaluate the clinical course, treatment,…”
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Aging, frailty and age-related diseases
Published in Biogerontology (Dordrecht) (01-10-2010)“…The concept of frailty as a medically distinct syndrome has evolved based on the clinical experience of geriatricians and is clinically well recognizable…”
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Senescence of the Human Immune System
Published in Journal of comparative pathology (2010)“…The umbrella term ‘immunosenescence’ is applied to describe age-associated failing systemic immunity and is believed to contribute to the increased incidence…”
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Exploratory study on immune phenotypes in Alzheimer’s disease and vascular dementia
Published in European journal of neurology (01-10-2020)“…Background and purpose The differentiation of Alzheimer’s disease (AD) dementia from vascular dementia (VaD) and mixed‐type dementia (mixed dementia) requires…”
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A Consideration of Biomarkers to be Used for Evaluation of Inflammation in Human Nutritional Studies
Published in British journal of nutrition (01-01-2013)“…To monitor inflammation in a meaningful way, the markers used must be valid: they must reflect the inflammatory process under study and they must be predictive…”
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From inflamm-aging to immune-paralysis: a slippery slope during aging for immune-adaptation
Published in Biogerontology (Dordrecht) (01-02-2016)“…Aging is accompanied by many physiological changes including those in the immune system. These changes are designated as immunosenescence indicating that age…”
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Journal Article Book Review -
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Highly active Cu/ZnO-Al catalyst for methanol synthesis: effect of aging on its structure and activity
Published in RSC advances (05-06-2018)“…The influence of aging of precipitates on the physical and catalytic properties of a copper/zinc oxide-aluminium (Cu/ZnO-Al) catalyst with an optimized…”
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Intracellular signalling pathways: targets to reverse immunosenescence
Published in Clinical and experimental immunology (01-01-2017)“…Summary Ageing is a very complex process, the result of the dysregulation of multiple systems interacting in many ways. A prominent change occurring with…”
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The frequency of interleukin‐1β‐producing monocytes is significantly associated with varicella‐zoster responses of nursing home residents
Published in Clinical and experimental immunology (01-07-2021)“…Summary Previous studies have demonstrated that the status of the T cell compartment and inflammation‐related factors are associated with the immunogenicity of…”
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Prognostic impact of the putative cancer stem cell markers ABCG2, CD133, ALDH1A1 and CD44V7/8 in metastatic melanoma
Published in British journal of dermatology (1951) (01-11-2017)Get full text
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Immunosenescence: impact in the young as well as the old?
Published in Mechanisms of ageing and development (01-04-1999)Get full text
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T Cell Assays and MIATA: The Essential Minimum for Maximum Impact
Published in Immunity (Cambridge, Mass.) (27-07-2012)“…[...]the current version of MIATA is a testimonial to the freedom and transparency of research and proves the ability of the research community to form…”
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No Immune Risk Profile among individuals who reach 100 years of age: Findings from the Swedish NONA immune longitudinal study
Published in Experimental gerontology (01-08-2007)“…In the present NONA immune longitudinal study, we investigate the previously identified Immune Risk Profile (IRP), defined by an inverted CD4/CD8 ratio and…”
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Sublingual gland neoplasms: clinicopathological study of 8 cases
Published in Medicina oral, patología oral y cirugía bucal (01-09-2021)“…BACKGROUNDSublingual gland neoplasms are very rare and the majority of them are malignant. The aim of this study was to evaluate the clinical course,…”
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Immunosenescence and cancer
Published in Critical reviews in oncology/hematology (2008)Get full text
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Human immunosenescence: does it have an infectious component?
Published in Annals of the New York Academy of Sciences (01-05-2006)“…The rate of acceleration of the frequency of death due to cardiovascular disease or cancer increases with age from middle age up to around 75-80 years,…”
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Proliferative index activity in oral squamous cell carcinoma: indication for postoperative radiotherapy?
Published in International journal of oral and maxillofacial surgery (01-10-2014)“…Abstract The predictive value of the Ki-67 labelling index and its relationship with radiosensitivity in oral squamous cell carcinoma (SCC) remains…”
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Unravelling the Structural Modification (Meso-Nano-) of Cu/ZnO-Al2O3 Catalysts for Methanol Synthesis by the Residual NaNO3 in Hydroxycarbonate Precursors
Published in Catalysts (01-11-2020)“…The effects of residual NaNO3 on the modification of Cu/ZnO-Al2O3 catalysts have been extensively documented, but the modification mechanism is so far unclear…”
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