Search Results - "Paweł Sachadyn"

From Bioink to Tissue: Exploring Chitosan-Agarose Composite in the Context of Printability and Cellular Behaviour by Mania, Szymon, Banach-Kopeć, Adrianna, Maciejewska, Natalia, Czerwiec, Katarzyna, Słonimska, Paulina, Deptuła, Milena, Baczyński-Keller, Jakub, Pikuła, Michał, Sachadyn, Paweł, Tylingo, Robert

“…This study presents an innovative method for producing thermosensitive bioink from chitosan hydrogels saturated with carbon dioxide and agarose. It focuses on…”
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Between therapy effect and false-positive result in animal experimentation by Sosnowski, Paweł, Sass, Piotr, Stanisławska-Sachadyn, Anna, Krzemiński, Michał, Sachadyn, Paweł

“…Despite the animal models’ complexity, researchers tend to reduce the number of animals in experiments for expenses and ethical concerns. This tendency makes…”
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Angiopoietin-like growth factor-derived peptides as biological activators of adipose-derived mesenchymal stromal cells by Schumacher, Adriana, Mucha, Piotr, Puchalska, Izabela, Deptuła, Milena, Wardowska, Anna, Tymińska, Agata, Filipowicz, Natalia, Mieczkowska, Alina, Sachadyn, Paweł, Piotrowski, Arkadiusz, Pikuła, Michał, Cichorek, Miroslawa

“…Adipose-derived mesenchymal stromal cells (AD-MSCs) are an essential issue in modern medicine. Extensive preclinical and clinical studies have shown that…”
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Release systems based on self-assembling RADA16-I hydrogels with a signal sequence which improves wound healing processes by Dzierżyńska, Maria, Sawicka, Justyna, Deptuła, Milena, Sosnowski, Paweł, Sass, Piotr, Peplińska, Barbara, Pietralik-Molińska, Zuzanna, Fularczyk, Martyna, Kasprzykowski, Franciszek, Zieliński, Jacek, Kozak, Maciej, Sachadyn, Paweł, Pikuła, Michał, Rodziewicz-Motowidło, Sylwia

“…Self-assembling peptides can be used for the regeneration of severely damaged skin. They can act as scaffolds for skin cells and as a reservoir of active…”
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Transcriptomic responses to wounding: meta-analysis of gene expression microarray data by Sass, Piotr Andrzej, Dąbrowski, Michał, Charzyńska, Agata, Sachadyn, Paweł

“…A vast amount of microarray data on transcriptomic response to injury has been collected so far. We designed the analysis in order to identify the genes…”
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Conserved motifs of MutL proteins by Banasik, Michał, Sachadyn, Paweł

“…The MutL protein is best known for its function in DNA mismatch repair (MMR). However, there is evidence to suggest that MutL is not only the linker connecting…”
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Immunophenotyping and transcriptional profiling of in vitro cultured human adipose tissue derived stem cells by Mieczkowska, Alina, Schumacher, Adriana, Filipowicz, Natalia, Wardowska, Anna, Zieliński, Maciej, Madanecki, Piotr, Nowicka, Ewa, Langa, Paulina, Deptuła, Milena, Zieliński, Jacek, Kondej, Karolina, Renkielska, Alicja, Buckley, Patrick G., Crossman, David K., Crowley, Michael R., Czupryn, Artur, Mucha, Piotr, Sachadyn, Paweł, Janus, Łukasz, Skowron, Piotr, Rodziewicz-Motowidło, Sylwia, Cichorek, Mirosława, Pikuła, Michał, Piotrowski, Arkadiusz

“…Adipose-derived stem cells (ASCs) have become an important research model in regenerative medicine. However, there are controversies regarding the impact of…”
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Changes in gene methylation patterns in neonatal murine hearts: Implications for the regenerative potential by Górnikiewicz, Bartosz, Ronowicz, Anna, Krzemiński, Michał, Sachadyn, Paweł

“…The neonatal murine heart is able to regenerate after severe injury; this capacity however, quickly diminishes and it is lost within the first week of life…”
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Functionalized Peptide Fibrils as a Scaffold for Active Substances in Wound Healing by Sawicka, Justyna, Iłowska, Emilia, Deptuła, Milena, Sosnowski, Paweł, Sass, Piotr, Czerwiec, Katarzyna, Chmielewska, Klaudia, Szymańska, Aneta, Pietralik-Molińska, Zuzanna, Kozak, Maciej, Sachadyn, Paweł, Pikuła, Michał, Rodziewicz-Motowidło, Sylwia

“…Technological developments in the field of biologically active peptide applications in medicine have increased the need for new methods for peptide delivery…”
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PTD4 Peptide Increases Neural Viability in an In Vitro Model of Acute Ischemic Stroke by Mazuryk, Jarosław, Puchalska, Izabela, Koziński, Kamil, Ślusarz, Magdalena J., Ruczyński, Jarosław, Rekowski, Piotr, Rogujski, Piotr, Płatek, Rafał, Wiśniewska, Marta Barbara, Piotrowski, Arkadiusz, Janus, Łukasz, Skowron, Piotr M., Pikuła, Michał, Sachadyn, Paweł, Rodziewicz-Motowidło, Sylwia, Czupryn, Artur, Mucha, Piotr

“…Ischemic stroke is a disturbance in cerebral blood flow caused by brain tissue ischemia and hypoxia. We optimized a multifactorial in vitro model of acute…”
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A Colorimetric Microplate Assay for DNA-Binding Activity of His-Tagged MutS Protein by Banasik, Michał, Sachadyn, Paweł

“…A simple microplate method was designed for rapid testing DNA-binding activity of proteins. The principle of the assay involves binding of tested DNA by…”
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In vitro affinity of Deinococcus radiodurans MutS towards mismatched DNA exceeds that of its orthologues from Escherichia coli and Thermus thermophilus by Banasik, Michał, Stanisławska-Sachadyn, Anna, Hildebrandt, Ewa, Sachadyn, Paweł

“…•D. radiodurans MutS was compared to that from E. coli and T. thermophilus.•D. radiodurans MutS exhibits superior efficiency of DNA mismatch binding in…”
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Transcriptional profile of in vitro expanded human epidermal progenitor cells for the treatment of non-healing wounds by Langa, Paulina, Wardowska, Anna, Zieliński, Jacek, Podolak-Popinigis, Justyna, Sass, Piotr, Sosnowski, Paweł, Kondej, Karolina, Renkielska, Alicja, Sachadyn, Paweł, Trzonkowski, Piotr, Pikuła, Michał

“…•Two-step enzymatic isolation method is effective to obtain epidermal progenitor cells.•Epidermal cells cultured in vitro express markers of stem cells.•Fibrin…”
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Imunofan-RDKVYR Peptide-Stimulates Skin Cell Proliferation and Promotes Tissue Repair by Sawicka, Justyna, Dzierżyńska, Maria, Wardowska, Anna, Deptuła, Milena, Rogujski, Piotr, Sosnowski, Paweł, Filipowicz, Natalia, Mieczkowska, Alina, Sass, Piotr, Pawlik, Anna, Hać, Aleksandra, Schumacher, Adriana, Gucwa, Magdalena, Karska, Natalia, Kamińska, Jolanta, Płatek, Rafał, Mazuryk, Jarosław, Zieliński, Jacek, Kondej, Karolina, Młynarz, Piotr, Mucha, Piotr, Skowron, Piotr, Janus, Łukasz, Herman-Antosiewicz, Anna, Sachadyn, Paweł, Czupryn, Artur, Piotrowski, Arkadiusz, Pikuła, Michał, Rodziewicz-Motowidło, Sylwia

“…Regeneration and wound healing are vital to tissue homeostasis and organism survival. One of the biggest challenges of today's science and medicine is finding…”
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Examination of epigenetic inhibitor zebularine in treatment of skin wounds in healthy and diabetic mice by Sass, Piotr, Sosnowski, Paweł, Kamińska, Jolanta, Deptuła, Milena, Skoniecka, Aneta, Zieliński, Jacek, Rodziewicz‐Motowidło, Sylwia, Pikuła, Michał, Sachadyn, Paweł

“…DNA methyltransferase inhibitor zebularine was proven to induce regeneration in the ear pinna in mice. We utilized a dorsal skin wound model to further…”
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The methylome and transcriptome of fetal skin: implications for scarless healing by Podolak-Popinigis, Justyna, Ronowicz, Anna, Dmochowska, Monika, Jakubiak, Agnieszka, Sachadyn, Pawe

“…Fetal skin is known to heal without scarring. In mice, the phenomenon is observed until the 16-17 day of gestation - the day of transition from scarless to…”
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Transcriptome profiling reveals distinctive traits of retinol metabolism and neonatal parallels in the MRL/MpJ mouse by Podolak-Popinigis, Justyna, Górnikiewicz, Bartosz, Ronowicz, Anna, Sachadyn, Paweł

“…The MRL/MpJ mouse is a laboratory inbred strain known for regenerative abilities which are manifested by scarless closure of ear pinna punch holes. Enhanced…”
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Genome-wide DNA methylation profiling of the regenerative MRL/MpJ mouse and two normal strains by Górnikiewicz, Bartosz, Ronowicz, Anna, Madanecki, Piotr, Sachadyn, Pawe

“…We aimed to identify the pivotal differences in the DNA methylation profiles between the regeneration capable MRL/MpJ mouse and reference mouse strains. Global…”
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A simple modification of PCR thermal profile applied to evade persisting contamination by Banasik, Michał, Stanisławska-Sachadyn, Anna, Sachadyn, Paweł

“…The polymerase chain reaction (PCR), one of the most commonly applied methods of diagnostics and molecular biology has a frustrating downside known as the…”
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Transcriptional activity of epigenetic remodeling genes declines in keratinocytes after in vitro expansion by Kamińska, Jolanta, Langa, Paulina, Deptuła, Milena, Zieliński, Jacek, Sachadyn, Paweł, Wardowska, Anna, Pikuła, Michał

“…In vitro expansion is an invaluable method to obtain keratinocytes in amounts necessary for effective transplantation therapies. In vitro cell culturing…”
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