Search Results - "Pawar, Vivek K"
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Engineered nanocrystal technology: In-vivo fate, targeting and applications in drug delivery
Published in Journal of controlled release (10-06-2014)“…Formulation of nanocrystals is a robust approach which can improve delivery of poorly water soluble drugs, a challenge pharmaceutical industry has been facing…”
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Targeting of gastrointestinal tract for amended delivery of protein/peptide therapeutics: Strategies and industrial perspectives
Published in Journal of controlled release (28-12-2014)“…Delivery of proteins/peptides to the gastrointestinal (GI) tract via peroral/oral route involves tremendous challenges due to unfavorable environmental…”
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Immunoadjuvant Chemotherapy of Visceral Leishmaniasis in Hamsters Using Amphotericin B-Encapsulated Nanoemulsion Template-Based Chitosan Nanocapsules
Published in Antimicrobial Agents and Chemotherapy (01-04-2013)“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Bioinspired Calcium Phosphate Nanoparticles Featuring as Efficient Carrier and Prompter for Macrophage Intervention in Experimental Leishmaniasis
Published in Pharmaceutical research (01-11-2016)“…Purpose To develop a biocompatible and bioresorbable calcium phosphate (CaP) nanoparticles (NPs) bearing Amphotericin B (AmB) with an aim to provide macrophage…”
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Perspectives of nanoemulsion assisted oral delivery of docetaxel for improved chemotherapy of cancer
Published in Drug delivery (12-02-2016)“…Nanoemulsions (NE) are one of the robust delivery tools for drugs due to their higher stability and efficacy. The purpose of present investigation is to…”
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Improved chemotherapy against breast cancer through immunotherapeutic activity of fucoidan decorated electrostatically assembled nanoparticles bearing doxorubicin
Published in International journal of biological macromolecules (01-02-2019)“…Immunotherapeutic nanoparticles (NPs) could be a viable option for delivering cytotoxic agents in a manner which suppresses their toxic manifestations…”
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Chitosan-Assisted Immunotherapy for Intervention of Experimental Leishmaniasis via Amphotericin B-Loaded Solid Lipid Nanoparticles
Published in Applied biochemistry and biotechnology (01-10-2014)“…Solid lipid nanoparticles (SLNs) have emerged as an excellent substitute over polymeric nanoparticles and, when incorporated with chitosan which activates the…”
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Immunotherapeutic vitamin E nanoemulsion synergies the antiproliferative activity of paclitaxel in breast cancer cells via modulating Th1 and Th2 immune response
Published in Journal of controlled release (28-12-2014)“…Paclitaxel (PTX) is used as first line treatment for metastatic breast cancer but the relief comes at a heavy cost in terms of accompanying adverse effects…”
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Chitosan coated PluronicF127 micelles for effective delivery of Amphotericin B in experimental visceral leishmaniasis
Published in International journal of biological macromolecules (01-12-2017)“…The goal of study was to develop micellar formulation of Amphotericin B (AmB) to improve its antileishmanial efficacy. AmB loaded pluronic F127 (PF 127)…”
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Paclitaxel-Loaded Colloidal Silica and TPGS-Based Solid Self-Emulsifying System Interferes Akt/mTOR Pathway in MDA-MB-231 and Demonstrates Anti-tumor Effect in Syngeneic Mammary Tumors
Published in AAPS PharmSciTech (09-11-2020)“…A solid self-emulsifying drug delivery system (SEDDS) of paclitaxel (PTX) was developed that could enhance its oral bioavailability and neutralize other…”
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Industrial perspective of gastroretentive drug delivery systems: physicochemical, biopharmaceutical, technological and regulatory consideration
Published in Expert opinion on drug delivery (01-05-2012)“…Gastroretentive drug delivery systems (GRDDS) can overcome drawbacks associated with oral drug delivery, by defeating natural physiological principles. Various…”
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Gastroretentive dosage forms: a review with special emphasis on floating drug delivery systems
Published in Drug delivery (01-02-2011)“…In the present era, gastroretentive dosage forms (GRDF) receive great attention because they can improve the performance of controlled release systems. An…”
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Fabrication of 3-O-sn-Phosphatidyl-L-serine Anchored PLGA Nanoparticle Bearing Amphotericin B for Macrophage Targeting
Published in Pharmaceutical research (01-03-2018)“…ABSTRACT Purpose To fabricate, characterize and evaluate 3-O-sn-Phosphatidyl-L-serine (PhoS) anchored PLGA nanoparticles for macrophage targeted therapeutic…”
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Trichotomous gastric retention of amorphous capecitabine: An attempt to overcome pharmacokinetic gap
Published in International journal of pharmaceutics (30-01-2015)“…[Display omitted] •Triple mechanism gastric retention owing to porous structure, swelling behavior and mucoadhesive nature.•Sustained drug release due to…”
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Chondroitin nanocapsules enhanced doxorubicin induced apoptosis against leishmaniasis via Th1 immune response
Published in International journal of biological macromolecules (01-08-2015)“…Current leishmaniasis treatment is strangled due to concealed residence of parasite and reduced host cell mediated immune response. To circumvent above…”
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Doxorubicin Hydrochloride Loaded Zymosan-Polyethylenimine Biopolymeric Nanoparticles for Dual ‘Chemoimmunotherapeutic’ Intervention in Breast Cancer
Published in Pharmaceutical research (01-09-2017)“…Objective To utilize nanoparticles produced by condensation of zymosan (an immunotherapeutic polysaccharide) with pegylated polyethylenimine (PEG-PEI) for dual…”
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Induction of Mitochondrial Cell Death and Reversal of Anticancer Drug Resistance via Nanocarriers Composed of a Triphenylphosphonium Derivative of Tocopheryl Polyethylene Glycol Succinate
Published in Molecular pharmaceutics (03-09-2019)“…We have devised a nanocarrier using “tocopheryl polyethylene glycol succinate (TPGS) conjugated to triphenylphosphonium cation” (TPP-TPGS) for improving the…”
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Bridging small interfering RNA with giant therapeutic outcomes using nanometric liposomes
Published in Journal of controlled release (28-12-2015)“…The scope of RNAi based therapeutics is unquestionable. However, if we dissect the current trend of clinical trials for afore mentioned drug class, some stark…”
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Development of docetaxel nanocapsules for improving in vitro cytotoxicity and cellular uptake in MCF-7 cells
Published in Drug development and industrial pharmacy (02-11-2015)“…The aim of this study was to fabricate docetaxel loaded nanocapsules (DTX-NCs) with a high payload using Layer-by-Layer (LbL) technique by successive coating…”
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Optimization Studies on Gastroretentive Floating System Using Response Surface Methodology
Published in AAPS PharmSciTech (01-03-2012)“…The aim of the present investigation was to develop and optimize gastroretentive floating system of amoxicillin for the efficient treatment of peptic ulcer…”
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