Search Results - "Pawar, Sandip V"
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Lignin: The green powerhouse for enzyme immobilization in biocatalysis and biosensing
Published in International journal of biological macromolecules (01-11-2024)“…Enzymes play an important role in diverse industries and are critical components of many industrial products, yet, their application is limited due to their…”
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2
Antibiofilm activity of truncated Staphylococcus aureus phenol soluble modulin α2 (SaΔ1Δ2PSMα2) against Candida auris in vitro and in an animal model of catheter-associated infection
Published in Microbial pathogenesis (01-11-2024)“…Candida auris has emerged as a major multidrug-resistant nosocomial pathogen. The organism exhibits a persistent colonising phenotype, and causes recalcitrant…”
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3
Green synthesis of lignin-based nanoparticles as a bio-carrier for targeted delivery in cancer therapy
Published in International journal of biological macromolecules (28-02-2023)“…Polymeric magnetic nanoparticles have shown higher efficacy in cancer diagnosis and treatment than conventional chemotherapies. Lignin is an abundantly…”
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4
Nanostructured lipid carriers: a promising drug carrier for targeting brain tumours
Published in Future journal of pharmaceutical sciences (08-04-2022)“…Background In recent years, the field of nanotechnology and nanomedicine has transformed the pharmaceutical industry with the development of novel drug…”
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5
A Walk Through the Maze of Secondary Metabolism in Orchids: A Transcriptomic Approach
Published in Frontiers in plant science (29-04-2022)“…Orchids have a huge reservoir of secondary metabolites making these plants of immense therapeutic importance. Their potential as curatives has been realized…”
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6
Metagenomic discovery of a novel transaminase for valorization of monoaromatic compounds
Published in RSC advances (01-01-2018)“…The profitability of next-generation biorefineries is acutely contingent on the discovery and utilization of biocatalysts that can valorize lignin. To this…”
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An Improved Whole-Cell Biosensor for the Discovery of Lignin-Transforming Enzymes in Functional Metagenomic Screens
Published in ACS synthetic biology (16-02-2018)“…The discovery and utilization of biocatalysts that selectively valorize lignocellulose is critical to the profitability of next-generation biorefineries. Here,…”
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8
Facially Amphiphilic Cholic Acid–Lysine Conjugates as Promising Antimicrobials
Published in ACS omega (03-03-2020)“…The emergence of multidrug-resistant microbes is a significant health concern posing a constant need for new antimicrobials. Membrane-targeting antibiotics are…”
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The Impending Renaissance in Discovery & Development of Natural Products
Published in Current topics in medicinal chemistry (01-01-2017)“…Antibiotics are wonder drugs. Unfortunately, owing to overuse, antibiotic resistance is now a serious problem. Society now finds itself in the post-antibiotic…”
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10
Gamut of glycolytic enzymes in vascular smooth muscle cell proliferation: Implications for vascular proliferative diseases
Published in Biochimica et biophysica acta. Molecular basis of disease (01-03-2024)“…Vascular smooth muscle cells (VSMCs) are the predominant cell type in the media of the blood vessels and are responsible for maintaining vascular tone…”
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A mild and metal-free synthesis of 2- and 1-alkyl/aryl/dialkyl-aminoquinolines and isoquinolines
Published in RSC advances (20-02-2020)“…A simple synthetic strategy has been developed for the synthesis of 2- and 1-alkyl/aryl/dialkylaminoquinolines and isoquinolines from the easily available…”
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12
Lignin-chitosan biocomposite film for antimicrobial activity: Fabrication, characterization and in-vitro evaluation
Published in Materials letters (15-04-2023)“…[Display omitted] •Biopolymers have gained great importance in biomedical applications.•Lignin- chitosan biocomppsite film was prepared by using…”
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Recent advances in pharmaceutical and biotechnological applications of lignin-based materials
Published in International journal of biological macromolecules (30-06-2023)“…Lignin, a versatile and abundant biomass-derived polymer, possesses a wide array of properties that makes it a promising material for biotechnological…”
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14
Synergism between microwave irradiation and enzyme catalysis in transesterification of ethyl-3-phenylpropanoate with n-butanol
Published in Bioresource technology (01-04-2012)“…[Display omitted] ► Lipase catalyzed transesterification of ethyl-3-phenylpropanoate in organic media. ► Immobilized Candida antarctica lipase B was found to…”
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15
Insights to Phenylalanine Ammonia Lyase (PAL) and Secondary Metabolism in Orchids: An in silico Approach
Published in Biochemical genetics (01-02-2024)“…The phenylalanine ammonia lyase (PAL) catalyses the first step of phenylpropanoid metabolic pathway which leads to the biosynthesis of a diverse group of…”
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16
Lipase catalyzed chemo-enzymatic synthesis of propranolol: A newer enzymatic approach
Published in Journal of the Indian Chemical Society (01-07-2023)“…The biocatalytic processes are greener and safer alternatives for synthesis of drug and drug intermediates. This study reports one such approach of…”
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Enantioselective Enzymatic Hydrolysis of rac-Mandelonitrile to R‑Mandelamide by Nitrile Hydratase Immobilized on Poly(vinyl alcohol)/Chitosan–Glutaraldehyde Support
Published in Industrial & engineering chemistry research (14-05-2014)“…Nitriles, amides and carboxylic acids have varied applications in active pharmaceutical intermediate (API), drug and chemical industry, and particularly in the…”
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Polyketide synthases (PKSs) of secondary metabolism: in silico identification and characterization in orchids
Published in Journal of biomolecular structure & dynamics (13-08-2023)“…Type III polyketide synthases (PKSs) catalyse the formation of an array of polyketides with diverse structures that play an important role in secondary…”
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Design, synthesis, biological evaluations and in silico studies of N-substituted 2,4-thiazolidinedione derivatives as potential a-glucosidase inhibitors
Published in Journal of biomolecular structure & dynamics (11-12-2023)“…Diabetes mellitus is considered as one of the principal global health urgencies of the twenty first century. In the present investigation, novel -substituted…”
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Synthesis, biological evaluation and in silico studies of 2-aminoquinolines and 1-aminoisoquinolines as antimicrobial agents
Published in Computational biology and chemistry (01-02-2023)“…The current study reports synthesis of 2-aminoquinolines and 1-aminoisoquinolines derivatives and their characterization. Further, in vitro studies were…”
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