Search Results - "Pawar, Nitin J."
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Expedient Synthesis of Core Disaccharide Building Blocks from Natural Polysaccharides for Heparan Sulfate Oligosaccharide Assembly
Published in Angewandte Chemie International Edition (16-12-2019)“…The complex sulfation motifs of heparan sulfate glycosaminoglycans (HS GAGs) play critical roles in many important biological processes. However, an…”
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2
Quaternary Indolizidine and Indolizidone Iminosugars as Potential Immunostimulating and Glycosidase Inhibitory Agents: Synthesis, Conformational Analysis, Biological Activity, and Molecular Docking Study
Published in Journal of medicinal chemistry (08-10-2015)“…New quaternary indolizidine iminosugars, with hydroxymethyl group at the ring junction, namely, C-8a-hydroxymethyl-1-deoxycastanospermine congeners 1a, 2a, 3a…”
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3
Expedient Synthesis of Core Disaccharide Building Blocks from Natural Polysaccharides for Heparan Sulfate Oligosaccharide Assembly
Published in Angewandte Chemie (16-12-2019)“…The complex sulfation motifs of heparan sulfate glycosaminoglycans (HS GAGs) play critical roles in many important biological processes. However, an…”
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4
Oxygen Imaging of a Rabbit Tumor Using a Human-Sized Pulse Electron Paramagnetic Resonance Imager
Published in Molecular imaging and biology (01-06-2024)“…Purpose Spatial heterogeneity in tumor hypoxia is one of the most important factors regulating tumor growth, development, aggressiveness, metastasis, and…”
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Multivalent presentation of carbohydrates by 3(14)-helical peptide templates: synthesis, conformational analysis using CD spectroscopy and saccharide recognition
Published in Organic & biomolecular chemistry (14-12-2015)“…A well defined 314-helical tetravalent β-galactopeptide site-specific functionalised template (SSFT) 1 was prepared containing d-galactose units, with free…”
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Inhibition of mitochondrial metabolism by (−)-jerantinine A: synthesis and biological studies in triple-negative breast cancer cells
Published in RSC medicinal chemistry (26-04-2023)“…A concise semi-synthesis of the Aspidosperma alkaloids, (−)-jerantinine A and (−)-melodinine P, and derivatives thereof, is reported. The novel compounds were…”
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α‑Geminal Dihydroxymethyl Piperidine and Pyrrolidine Iminosugars: Synthesis, Conformational Analysis, Glycosidase Inhibitory Activity, and Molecular Docking Studies
Published in Journal of organic chemistry (21-09-2012)“…The Jocic–Reeve and Corey–Link type reaction of dichloromethyllithium with suitably protected 5-keto-hexofuranoses followed by treatment with sodium azide and…”
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Molecular architecture with carbohydrate functionalized β-peptides adopting 314-helical conformation
Published in Beilstein journal of organic chemistry (2014)“…Carbohydrate recognition is essential in cellular interactions and biological processes. It is characterized by structural diversity, multivalency and…”
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Molecular architecture with carbohydrate functionalized β-peptides adopting 3 14 -helical conformation
Published in Beilstein journal of organic chemistry (28-04-2014)“…Carbohydrate recognition is essential in cellular interactions and biological processes. It is characterized by structural diversity, multivalency and…”
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