Search Results - "Pawar, Nisha R."

Membrane-Anchored Serine Proteases and Protease-Activated Receptor-2-Mediated Signaling: Co-Conspirators in Cancer Progression by Pawar, Nisha R, Buzza, Marguerite S, Antalis, Toni M

“…Pericellular proteolysis provides a significant advantage to developing tumors through the ability to remodel the extracellular matrix, promote cell invasion…”
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Fibrinolysis and Inflammation in Venous Thrombus Resolution by Mukhopadhyay, Subhradip, Johnson, Tierra A, Duru, Nadire, Buzza, Marguerite S, Pawar, Nisha R, Sarkar, Rajabrata, Antalis, Toni M

“…Clinical observations and accumulating laboratory evidence support a complex interplay between coagulation, inflammation, innate immunity and fibrinolysis in…”
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Intersection of Coagulation and Fibrinolysis by the Glycosylphosphatidylinositol (GPI)-Anchored Serine Protease Testisin by Buzza, Marguerite S, Pawar, Nisha R, Strong, Amando A, Antalis, Toni M

“…Hemostasis is a delicate balance between coagulation and fibrinolysis that regulates the formation and removal of fibrin, respectively. Positive and negative…”
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Matriptase drives dissemination of ovarian cancer spheroids by a PAR-2/PI3K/Akt/MMP9 signaling axis by Pawar, Nisha R, Buzza, Marguerite S, Duru, Nadire, Strong, Amando A, Antalis, Toni M

“…The transmembrane serine protease matriptase is a key regulator of both barrier-disruptive and protective epithelial cell-cell interactions. Elevated…”
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Selective targeting of metastatic ovarian cancer using an engineered anthrax prodrug activated by membrane-anchored serine proteases by Duru, Nadire, Pawar, Nisha R, Martin, Erik W, Buzza, Marguerite S, Conway, Gregory D, Lapidus, Rena G, Liu, Shihui, Reader, Jocelyn, Rao, Gautam G, Roque, Dana M, Leppla, Stephen H, Antalis, Toni M

“…Treatments for advanced and recurrent ovarian cancer remain a challenge due to a lack of potent, selective, and effective therapeutics. Here, we developed the…”
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PRSS21/testisin inhibits ovarian tumor metastasis and antagonizes proangiogenic angiopoietins ANG2 and ANGPTL4 by Conway, Gregory D., Buzza, Marguerite S., Martin, Erik W., Duru, Nadire, Johnson, Tierra A., Peroutka, Raymond J., Pawar, Nisha R., Antalis, Toni M.

“…Ovarian cancer is the leading cause of death among all the gynecological cancers in the USA. Ovarian cancer employs a unique mode of metastasis, as exfoliated…”
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Correction to: PRSS21/testisin inhibits ovarian tumor metastasis and antagonizes proangiogenic angiopoietins ANG2 and ANGPTL4 by Conway, Gregory D., Buzza, Marguerite S., Martin, Erik W., Duru, Nadire, Johnson, Tierra A., Peroutka, Raymond J., Pawar, Nisha R., Antalis, Toni M.

“…The affiliation of Erik W. Martin is corrected in this paper…”
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Improving Cancer Detection and Treatment with Liquid Biopsies and ptDNA by Kessler, Michael D, Pawar, Nisha R, Martin, Stuart S, Antalis, Toni M, O'Connor, Timothy D

“…Liquid biopsy, or the capacity to noninvasively isolate and analyze plasma tumor DNA (ptDNA) using blood samples, represents an important tool for modern…”
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Protease‐activated receptor 2 (PAR‐2) biased agonism in ovarian cancer progression by Pawar, Nisha R., Duru, Nadire, Conway, Gregory D., Antalis, Toni M.

“…Ovarian cancer is one of the most fatal gynecological malignancies due to its delayed clinical presentation, indicating a need to investigate molecular…”
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