Search Results - "Pavone, S."
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Interrogating Biology with Force: Single Molecule High-Resolution Measurements with Optical Tweezers
Published in Biophysical journal (17-09-2013)“…Single molecule force spectroscopy methods, such as optical and magnetic tweezers and atomic force microscopy, have opened up the possibility to study…”
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2
Confocal light sheet microscopy: micron-scale neuroanatomy of the entire mouse brain
Published in Optics express (27-08-2012)“…Elucidating the neural pathways that underlie brain function is one of the greatest challenges in neuroscience. Light sheet based microscopy is a cutting edge…”
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3
Highly inclined light sheet allows volumetric super-resolution imaging of efflux pumps distribution in bacterial biofilms
Published in Scientific reports (05-06-2024)“…Bacterial biofilms are highly complex communities in which isogenic bacteria display different gene expression patterns and organize in a three-dimensional…”
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4
Dissecting Neuronal Activation on a Brain-Wide Scale With Immediate Early Genes
Published in Frontiers in neuroscience (23-10-2020)“…Visualizing neuronal activation on a brain-wide scale yet with cellular resolution is a fundamental technical challenge for neuroscience. This would enable…”
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Generation of non-diffractive Bessel beams by inward cylindrical traveling wave aperture distributions
Published in Optics express (28-07-2014)“…The focusing capabilities of an inward cylindrical traveling wave aperture distribution and the non-diffractive behaviour of its radiated field are analyzed…”
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6
α-catenin switches between a slip and an asymmetric catch bond with F-actin to cooperatively regulate cell junction fluidity
Published in Nature communications (03-03-2022)“…α-catenin is a crucial protein at cell junctions that provides connection between the actin cytoskeleton and the cell membrane. At adherens junctions (AJs),…”
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7
Effects of two different probiotics on microflora, morphology, and morphometry of gut in organic laying hens
Published in Poultry science (01-11-2016)“…The current study investigated the effects of Lactobacillus acidophilus and Bacillus subtilis, used as probiotics, on the microflora, morphology, and…”
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Development of Light-Responsive Liquid Crystalline Elastomers to Assist Cardiac Contraction
Published in Circulation research (12-04-2019)“…RATIONALE:Despite major advances in cardiovascular medicine, heart disease remains a leading cause of death worldwide. However, the field of tissue engineering…”
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Group ICA of wide-field calcium imaging data reveals the retrosplenial cortex as a major contributor to cortical activity during anesthesia
Published in Frontiers in cellular neuroscience (10-05-2024)“…Large-scale cortical dynamics play a crucial role in many cognitive functions such as goal-directed behaviors, motor learning and sensory processing. It is…”
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10
Partitioning and confinement of GM1 ganglioside induced by amyloid aggregates
Published in FEBS letters (02-05-2013)“…•Co-localization of GM1 with Aβ1–42 and amylin aggregates supported by in situ PLA.•Tracking of single GM1 reveals interaction with Aβ oligomers and amylin…”
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Optical mapping of neuronal activity during seizures in zebrafish
Published in Scientific reports (08-06-2017)“…Mapping neuronal activity during the onset and propagation of epileptic seizures can provide a better understanding of the mechanisms underlying this pathology…”
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12
Sliding of a single lac repressor protein along DNA is tuned by DNA sequence and molecular switching
Published in Nucleic acids research (01-06-2018)“…Abstract In any living cell, genome maintenance is carried out by DNA-binding proteins that recognize specific sequences among a vast amount of DNA. This…”
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Large-scale automated identification of mouse brain cells in confocal light sheet microscopy images
Published in Bioinformatics (01-09-2014)“…Recently, confocal light sheet microscopy has enabled high-throughput acquisition of whole mouse brain 3D images at the micron scale resolution. This poses the…”
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14
In vivo single branch axotomy induces GAP-43-dependent sprouting and synaptic remodeling in cerebellar cortex
Published in Proceedings of the National Academy of Sciences - PNAS (25-06-2013)“…Plasticity in the central nervous system in response to injury is a complex process involving axonal remodeling regulated by specific molecular pathways. Here,…”
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15
Transverse circular-polarized Bessel beam generation by inward cylindrical aperture distribution
Published in Optics express (16-05-2016)“…In this paper the focusing capability of a radiating aperture implementing an inward cylindrical traveling wave tangential electric field distribution directed…”
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16
Toward a High-Resolution Reconstruction of 3D Nerve Fiber Architectures and Crossings in the Brain Using Light Scattering Measurements and Finite-Difference Time-Domain Simulations
Published in Physical review. X (01-04-2020)“…Unraveling the structure and function of the brain requires a detailed knowledge about the neuronal connections, i.e., the spatial architecture of the nerve…”
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17
Deep learning-based localization algorithms on fluorescence human brain 3D reconstruction: a comparative study using stereology as a reference
Published in Scientific reports (25-06-2024)“…3D reconstruction of human brain volumes at high resolution is now possible thanks to advancements in tissue clearing methods and fluorescence microscopy…”
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18
Defects in T-tubular electrical activity underlie local alterations of calcium release in heart failure
Published in Proceedings of the National Academy of Sciences - PNAS (21-10-2014)“…Significance The plasma membrane of cardiac myocytes contains complex invaginations known as transverse tubules (T-tubules). In heart failure, T-tubule loss is…”
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19
Palette of fluorinated voltage-sensitive hemicyanine dyes
Published in Proceedings of the National Academy of Sciences - PNAS (11-12-2012)“…Optical recording of membrane potential permits spatially resolved measurement of electrical activity in subcellular regions of single cells, which would be…”
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Thermal Transitions of Fibrillar Collagen Unveiled by Second-Harmonic Generation Microscopy of Corneal Stroma
Published in Biophysical journal (19-09-2012)“…The thermal transitions of fibrillar collagen are investigated with second-harmonic generation polarization anisotropy microscopy. Second-harmonic generation…”
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