Search Results - "Pavone, Francesca"

Novel Spirotetracyclic Zwitterionic Dual H1/5-HT2A Receptor Antagonists for the Treatment of Sleep Disorders by Gianotti, Massimo, Botta, Maurizio, Brough, Stephen, Carletti, Renzo, Castiglioni, Emiliano, Corti, Corrado, Dal-Cin, Michele, Delle Fratte, Sonia, Korajac, Denana, Lovric, Marija, Merlo, Giancarlo, Mesic, Milan, Pavone, Francesca, Piccoli, Laura, Rast, Slavko, Roscic, Maja, Sava, Anna, Smehil, Mario, Stasi, Luigi, Togninelli, Andrea, Wigglesworth, Mark J

“…Histamine H1 and serotonin 5-HT2A receptors mediate two different mechanisms involved in sleep regulation: H1 antagonists are sleep inducers, while 5-HT2A…”
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Comorbidity prevalence and treatment outcome in children and adolescents with ADHD by Reale, Laura, Bartoli, Beatrice, Cartabia, Massimo, Zanetti, Michele, Costantino, Maria Antonella, Canevini, Maria Paola, Termine, Cristiano, Bonati, Maurizio

“…Although ADHD comorbidity has been widely studied, some issues remain unsolved. This multicenter observational study aims to examine comorbid psychiatric…”
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SAR evolution towards potent C-terminal carboxamide peptide inhibitors of Zika virus NS2B-NS3 protease by Colarusso, Stefania, Ferrigno, Federica, Ponzi, Simona, Pavone, Francesca, Conte, Immacolata, Abate, Luigi, Beghetto, Elisa, Missineo, Antonino, Amaudrut, Jerome, Bresciani, Alberto, Paonessa, Giacomo, Tomei, Licia, Montalbetti, Christian, Bianchi, Elisabetta, Toniatti, Carlo, Ontoria, Jesus M.

“…[Display omitted] Zika virus (ZIKV) is a member of the Flaviviridae family that can cause neurological disorders and congenital malformations. The NS2B-NS3…”
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Impact of co-morbid attention-deficit and hyperactivity disorder on cognitive function in male children with Tourette syndrome: A controlled study by Termine, Cristiano, Luoni, Chiara, Fontolan, Stefania, Selvini, Claudia, Perego, Livia, Pavone, Francesca, Rossi, Giorgio, Balottin, Umberto, Cavanna, Andrea E

“…Abstract Tourette syndrome (TS) and attention-deficit and hyperactivity disorder (ADHD) are co-morbid neurodevelopmental conditions affecting more commonly…”
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In vitro evaluation of antioxidant activity by electrophoresis and high performance liquid chromatography by Grippa, Eleonora, Pavone, Francesca, Gatto, Maria Teresa, Petrucci, Rita, Marrosu, Giancarlo, Silvestrini, Bruno, Saso, Luciano

“…Two methods for the analysis of antioxidants, based on polyacrylamide gel electrophoresis (PAGE) and gel permeation high performance liquid chromatography…”
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19 Impact of co-morbid attention-deficit and hyperactivity disorder on cognitive function in male children with tourette syndrome: a controlled study by Cavanna, Andrea E, Luoni, Chiara, Fontolan, Stefania, Selvini, Claudia, Perego, Livia, Pavone, Francesca, Rossi, Giorgio, Balottin, Umberto, Termine, Cristiano

“…ObjectiveNeuropsychological studies have highlighted the presence of specific cognitive deficits in two neurodevelopmental disorders affecting more commonly…”
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The multiple phenotypes of Tourette syndrome and attention-deficit hyperactivity disorder by Termine, Cristiano, Luoni, Chiara, Fontolan, Stefania, Selvini, Claudia, Perego, Livia, Pavone, Francesca, Rossi, Giorgio, Balottin, Umberto, Cavanna, Andrea E

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Asymmetric route to spirotetracyclic (1S)-5′,11′-dihydro-3H-spiro[cyclopentane-1,10′-dibenzo[a,d]cyclohepten]-3-one derivatives by Gianotti, Massimo, Andreotti, Daniele, Casotto, Davide, Mattioli, Mario, Mingardi, Anna, Pavone, Francesca, Profeta, Roberto, Valente, Filippo

“…A new synthetic pathway to the final compound 1-[(1S)-5’,11’-dihydrospiro[cyclopentane-1,10’-dibenzo[a,d]cyclohepten]-3-yl]-3-azetidinecarboxylic acid (1) was…”
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Synthesis and Pharmacological Characterization of Novel Druglike Corticotropin-Releasing Factor 1 Antagonists by Fabio, Romano Di, St-Denis, Yves, Sabbatini, Fabio M, Andreotti, Daniele, Arban, Roberto, Bernasconi, Giovanni, Braggio, Simone, Blaney, Frank E, Capelli, Anna M, Castiglioni, Emiliano, Modugno, Enza Di, Donati, Daniele, Fazzolari, Elettra, Ratti, Emiliangelo, Feriani, Aldo, Contini, Stefania, Gentile, Gabriella, Ghirlanda, Damiano, Provera, Stefano, Marchioro, Carla, Roberts, Karen L, Mingardi, Anna, Mattioli, Mario, Nalin, Arnaldo, Pavone, Francesca, Spada, Simone, Trist, David G, Worby, Angela

“…To identify new CRF1 receptor antagonists, an attempt to modify the bis-hetherocycle moiety present in the top region of the dihydropirrole[2,3]pyridine…”
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Italian regional health service costs for diagnosis and 1-year treatment of ADHD in children and adolescents by Casadei, Gianluigi, Cartabia, Massimo, Reale, Laura, Costantino, Maria Antonella, Bonati, Maurizio

“…The main aim of this study was to estimate the costs associated with diagnostic assessment and 1-year therapy in children and adolescents enrolled in 18 ADHD…”
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Novel substituted tetrahydrotriazaacenaphthylene derivatives as potent CRF1 receptor antagonists by GENTILE, Gabriella, DI FABIO, Romano, PAVONE, Francesca, SABBATINI, Fabio Maria, ST-DENIS, Yves, GRAZIA ZAMPORI, Maria, VITULLI, Giovanni, WORBY, Angela

“…Corticotropin-releasing factor (CRF), a 41 amino acid peptide neurohormone synthesised by specific hypothalamic nuclei in the brain, is implicated in…”
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The usefulness of the Revised Psychoeducational Profile for the assessment of preschool children with pervasive developmental disorders by Portoghese, Claudia, Buttiglione, Maura, Pavone, Francesca, Lozito, Vito, De Giacomo, Andrea, Martinelli, Domenico, Margari, Lucia

“…Data from the Psychoeducational Profile—Revised (PEP—R) were analysed in a sample of 46 children, aged from 1.7 to 5.11 years, of whom 21 had autistic disorder…”
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Novel imidazobenzazepine derivatives as dual H 1/5-HT 2A antagonists for the treatment of sleep disorders by Gianotti, Massimo, Corti, Corrado, Fratte, Sonia Delle, Di Fabio, Romano, Leslie, Colin P., Pavone, Francesca, Piccoli, Laura, Stasi, Luigi, Wigglesworth, Mark J.

“…Application of a zwitterionic approach successfully delivered a class of high quality leads, 3-[4-(3-R 1-2-R-5H-imidazo[1,2-…”
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Discovery Process and Characterization of Novel Carbohydrazide Derivatives as Potent and Selective GHSR1a Antagonists by Sabbatini, Fabio Maria, Di Fabio, Romano, Corsi, Mauro, Cavanni, Paolo, Bromidge, Steve M., St-Denis, Yves, D'Adamo, Lucilla, Contini, Stefania, Rinaldi, Marilisa, Guery, Sebastien, Savoia, Chiara, Mundi, Claudia, Perini, Benedetta, Carpenter, Andrew J., Dal Forno, Giovanna, Faggioni, Federico, Tessari, Michela, Pavone, Francesca, Di Francesco, Carla, Buson, Alberto, Mattioli, Mario, Perdona', Elisabetta, Melotto, Sergio

“…Ghrelins: don't feed them after dark! A novel class of highly potent and selective growth hormone secretagogue receptor 1a (GHSR1a) antagonists has been…”
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Novel imidazobenzazepine derivatives as dual H1/5-HT2A antagonists for the treatment of sleep disorders by GIANOTTI, Massimo, CORTI, Corrado, DELLE FRATTE, Sonia, DI FABIO, Romano, LESLIE, Colin P, PAVONE, Francesca, PICCOLI, Laura, STASI, Luigi, WIGGLESWORTH, Mark J

“…A novel imidazobenzazepine template (5a) with potent dual H(1)/5-HT(2A) antagonist activity was identified. Application of a zwitterionic approach to this…”
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Novel Spirotetracyclic Zwitterionic Dual H 1 /5-HT 2A Receptor Antagonists for the Treatment of Sleep Disorders by Gianotti, Massimo, Botta, Maurizio, Brough, Stephen, Carletti, Renzo, Castiglioni, Emiliano, Corti, Corrado, Dal-Cin, Michele, Delle Fratte, Sonia, Korajac, Denana, Lovric, Marija, Merlo, Giancarlo, Mesic, Milan, Pavone, Francesca, Piccoli, Laura, Rast, Slavko, Roscic, Maja, Sava, Anna, Smehil, Mario, Stasi, Luigi, Togninelli, Andrea, Wigglesworth, Mark J.

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Novel carbazole derivatives as NPY Y1 antagonists by Leslie, Colin P., Fabio, Romano Di, Bonetti, Francesca, Borriello, Manuela, Braggio, Simone, Forno, Giovanna Dal, Donati, Daniele, Falchi, Alessandro, Ghirlanda, Damiano, Giovannini, Riccardo, Pavone, Francesca, Pecunioso, Angelo, Pentassuglia, Giorgio, Pizzi, Domenica A., Rumboldt, Giovanna, Stasi, Luigi

“…A series of carbazoles showing antagonist activity at the NPY Y1 receptor were prepared and characterised. Compound 13 combines potent activity with good brain…”
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Novel substituted tetrahydrotriazaacenaphthylene derivatives as potent CRF 1 receptor antagonists by Gentile, Gabriella, Di Fabio, Romano, Pavone, Francesca, Sabbatini, Fabio Maria, St-Denis, Yves, Zampori, Maria Grazia, Vitulli, Giovanni, Worby, Angela

“…Novel unsaturated tetrahydrotriazaacenaphthylenes have been identified as potent and selective CRF 1 receptor antagonists showing good oral pharmacokinetic…”
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Heteroaryl-Substituted 4-(1H-pyrazol-1-yl)-5,6-dihydro-1H-pyrrolo[2,3-d]pyrimidine Derivatives as Potent and Selective Corticotropin-Releasing Factor Receptor-1 Antagonists by Sabbatini, Fabio Maria, Di Fabio, Romano, St-Denis, Yves, Capelli, Anna-Maria, Castiglioni, Emiliano, Contini, Stefania, Donati, Daniele, Fazzolari, Elettra, Gentile, Gabriella, Micheli, Fabrizio, Pavone, Francesca, Rinaldi, Marilisa, Pasquarello, Alessandra, Zampori, Maria Grazia, Di Felice, Pina, Zarantonello, Paola, Arban, Roberto, Perini, Benedetta, Vitulli, Giovanni, Benedetti, Roberto, Oliosi, Beatrice, Worby, Angela

“…Potent and selective CRF1 receptor antagonists based on the 5,6‐dihydro‐1H‐pyrrolo[2,3‐d]pyrimidines 2 were discovered and characterized. Identification of two…”
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Cyclopenta[d]pyrimidines and Dihydropyrrolo[2,3-d]pyrimidines as Potent and Selective Corticotropin-Releasing Factor 1 Receptor Antagonists by Arban, Roberto, Benedetti, Roberto, Bonanomi, Giorgio, Capelli, Anna-Maria, Castiglioni, Emiliano, Contini, Stefania, Degiorgis, Fabio, Di Felice, Pina, Donati, Daniele, Fazzolari, Elettra, Gentile, Gabriella, Marchionni, Chiara, Marchioro, Carla, Messina, Flavia, Micheli, Fabrizio, Oliosi, Beatrice, Pavone, Francesca, Pasquarello, Alessandra, Perini, Benedetta, Rinaldi, Marilisa, Sabbatini, Fabio M., Vitulli, Giovanni, Zarantonello, Paola, Di Fabio, Romano, St-Denis, Yves

“…Two new classes of potent and selective CRF1 receptor antagonists are presented. Exploration of general templates 3 and 4 through modifications of the top…”
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