Search Results - "Pavlovich, Polina V"
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Single-cell transcriptomics identifies CD44 as a marker and regulator of endothelial to haematopoietic transition
Published in Nature communications (29-01-2020)“…The endothelial to haematopoietic transition (EHT) is the process whereby haemogenic endothelium differentiates into haematopoietic stem and progenitor cells…”
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Multilayer omics analysis reveals a non-classical retinoic acid signaling axis that regulates hematopoietic stem cell identity
Published in Cell stem cell (06-01-2022)“…Hematopoietic stem cells (HSCs) rely on complex regulatory networks to preserve stemness. Due to the scarcity of HSCs, technical challenges have limited our…”
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Prenatal inflammation perturbs murine fetal hematopoietic development and causes persistent changes to postnatal immunity
Published in Cell reports (Cambridge) (22-11-2022)“…Adult hematopoietic stem and progenitor cells (HSPCs) respond directly to inflammation and infection, causing both acute and persistent changes to quiescence,…”
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