Search Results - "Pavlov, Vasile I"

Extracellular Vesicle Injection Improves Myocardial Function and Increases Angiogenesis in a Swine Model of Chronic Ischemia by Potz, Brittany A, Scrimgeour, Laura A, Pavlov, Vasile I, Sodha, Neel R, Abid, M Ruhul, Sellke, Frank W

“…Mesenchymal stem cell-derived extracellular vesicles (EVs) are believed to be cardioprotective in myocardial infarct. The objective of this study was to…”
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Mannose-binding lectin-associated serine protease-1 is a significant contributor to coagulation in a murine model of occlusive thrombosis by La Bonte, Laura R, Pavlov, Vasile I, Tan, Ying S, Takahashi, Kazue, Takahashi, Minoru, Banda, Nirmal K, Zou, Chenhui, Fujita, Teizo, Stahl, Gregory L

“…Bleeding disorders and thrombotic complications constitute a major cause of death and disability worldwide. Although it is known that the complement and…”
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Human mannose-binding lectin inhibitor prevents Shiga toxin-induced renal injury by Ozaki, Masayuki, Kang, Yulin, Tan, Ying Siow, Pavlov, Vasile I, Liu, Bohan, Boyle, Daniel C, Kushak, Rafail I, Skjoedt, Mikkel-Ole, Grabowski, Eric F, Taira, Yasuhiko, Stahl, Gregory L

“…Hemolytic uremic syndrome caused by Shiga toxin-producing Escherichia coli (STEC HUS) is a worldwide endemic problem, and its pathophysiology is not fully…”
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Endogenous and Natural Complement Inhibitor Attenuates Myocardial Injury and Arterial Thrombogenesis by PAVLOV, Vasile I, SKJOEDT, Mikkel-Ole, YING SIOW TAN, ROSBJERG, Anne, GARRED, Peter, STAHL, Gregory L

“…Coagulation disorders and reperfusion of ischemic myocardium are major causes of morbidity and mortality. Lectin pathway initiation complexes are composed of…”
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Robust effect of metabolic syndrome on major metabolic pathways in the myocardium by Karimi, Maryam, Pavlov, Vasile I, Ziegler, Olivia, Sriram, Nivedita, Yoon, Se-Young, Agbortoko, Vahid, Alexandrova, Stoiana, Asara, John, Sellke, Frank W, Sturek, Michael, Feng, Jun, Alexandrov, Boian S, Usheva, Anny

“…Although the high-fat-diet-induced metabolic syndrome (MetS) is a precursor of human cardiac pathology, the myocardial metabolic state in MetS is far from…”
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Human Mannose-Binding Lectin Inhibitor Prevents Myocardial Injury and Arterial Thrombogenesis in a Novel Animal Model by Pavlov, Vasile I, Tan, Ying S, McClure, Erin E, La Bonte, Laura R, Zou, Chenhui, Gorsuch, William B, Stahl, Gregory L

“…Myocardial infarction and coagulation disorders are leading causes of disability and death in the world. An important role of the lectin complement pathway in…”
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Linking erythropoietin to Treg-dependent allograft survival through myeloid cells by Horwitz, Julian K, Bin, Sofia, Fairchild, Robert L, Keslar, Karen S, Yi, Zhengzi, Zhang, Weijia, Pavlov, Vasile I, Li, Yansui, Madsen, Joren C, Cravedi, Paolo, Heeger, Peter S

“…Erythropoietin (EPO) has multiple nonerythropoietic functions, including immune modulation, but EPO's effects in transplantation remain incompletely…”
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T cell-derived tumor necrosis factor induces cytotoxicity by activating RIPK1-dependent target cell death by Chun, Nicholas, Ang, Rosalind L, Chan, Mark, Fairchild, Robert L, Baldwin, 3rd, William M, Horwitz, Julian K, Gelles, Jesse D, Chipuk, Jerry Edward, Kelliher, Michelle A, Pavlov, Vasile I, Li, Yansui, Homann, Dirk, Heeger, Peter S, Ting, Adrian T

“…TNF ligation of TNF receptor 1 (TNFR1) promotes either inflammation and cell survival by (a) inhibiting RIPK1's death-signaling function and activating NF-κB…”
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Absence of Mannose-Binding Lectin Prevents Hyperglycemic Cardiovascular Complications by Pavlov, Vasile I, La Bonte, Laura R, Baldwin, William M, Markiewski, Maciej M, Lambris, John D, Stahl, Gregory L

“…Diabetes, stress, pharmaceuticals, surgery, and physical trauma can lead to hyperglycemic conditions. A consistent relationship has been found between chronic…”
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Targeting Mannose-Binding Lectin Confers Long-Lasting Protection With a Surprisingly Wide Therapeutic Window in Cerebral Ischemia by ORSINI, Franca, VILLA, Pia, PALADINI, Alessandra, MICOTTI, Edoardo, RIBEIRO-VIANA, Renato, ROJO, Javier, PAVLOV, Vasile I, STAHL, Gregory L, BERNARDI, Anna, GOBBI, Marco, DE SIMONI, Maria-Grazia, PARRELLA, Sara, ZANGARI, Rosalia, ZANIER, Elisa R, GESUETE, Raffaella, STRAVALACI, Matteo, FUMAGALLI, Stefano, OTTRIA, Roberta, REINA, Jose J

“…The involvement of the complement system in brain injury has been scarcely investigated. Here, we document the pivotal role of mannose-binding lectin (MBL),…”
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Complement 3 is involved with ventilator-induced lung injury by Takahashi, Kazue, Saha, Dalia, Shattino, Ivany, Pavlov, Vasile I., Stahl, Gregory L., Finnegan, Paul, Melo, Marcos F. Vidal

“…Humoral molecules can trigger injury on mechanically stressed and damaged tissue. We have studied the role of complement 3 (C3) in a mouse model of…”
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Endogenous and natural complement inhibitor attenuates myocardial injury and arterial thrombogenesis by Skjoedt, Mikkel-Ole, Pavlov, Vasile I, Tan, Ying Siow, Rosbjerg, Anne, Garred, Peter, Stahl, Gregory L

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Murine hyperglycemic vasculopathy and cardiomyopathy: whole-genome gene expression analysis predicts cellular targets and regulatory networks influenced by mannose binding lectin by Zou, Chenhui, La Bonte, Laura R, Pavlov, Vasile I, Stahl, Gregory L

“…Hyperglycemia, in the absence of type 1 or 2 diabetes, is an independent risk factor for cardiovascular disease. We have previously demonstrated a central role…”
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Targeting MBL in cerebral ischemia induces long lasting protection with a wide therapeutic window by Orsini, Franca, Parrella, Sara, Villa, Pia, Zangari, Rosalia, Zanier, Elisa R, Stravalaci, Matteo, Fumagalli, Stefano, Ottria, Roberta, Reina, Jose, Paladini, Alessandra, Micotti, Edoardo, Pavlov, Vasile I, Stahl, Gregory, Bernardi, Anna, Gobbi, Marco, De Simoni, Maria-Grazia

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Myocardial Ischemia/Reperfusion injury is mediated by polymorphonuclear neutrophils through direct activation of Phospholipase D (PLD) and mTOR by Ganesan, Ramya, Henkels, Karen M, Pavlov, Vasile I, Stahl, Gregory L, Gomez-Cambronero, Julian

“…Abstract During ischemia/reperfusion injury (I/RI), leukocytes release cytokines and exacerbate inflammation causing cardiac dysfunction, while neutrophils…”
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The MBL‐complex is necessary for FeCl3‐mediated thrombosis by Pavlov, Vasile I., La Bonte, Laura, Takahashi, Kazue, Stahl, Gregory L.

“…Occlusive thrombosis, resulting from atherosclerotic plaque rupture or restenosis plays an important role in the onset of two major causes of death in…”
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MBL-Associated Serine Protease -1 (MASP-1) is a Significant Contributor to Coagulation in a Murine Model of Occlusive Thrombosis by La Bonte, Laura R, Pavlov, Vasile I, Tan, Ying S, Takahashi, Kazue, Takahashi, Minoru, Banda, Nirmal K, Zou, Chenhui, Fujita, Teizo, Stahl, Gregory L

“…Bleeding disorders and thrombotic complications constitute a major cause of death and disability worldwide. While it’s known that the complement and…”
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Absence of MBL prevents hyperglycemic cardiovascular complications by Pavlov, Vasile I., La Bonte, Laura R., Markiewski, Maciej M., Lambris, John D., Stahl, Gregory L.

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Abstract 14431: Polar Metabolomics Uncovers Robust Effect of Metabolic Syndrome on Cardiac Spermine and Spermidine and Their Acetylation by Usheva, Anny S, Yoon, Se-Young, Feng, Jun, Pavlov, Vasile I

“…IntroductionAs the mechanisms that underlie the inflammatory shift from cardiac ischemia in patients with metabolic syndrome (MetS) and coronary artery disease…”
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Abstract 15367: Extracellular Vesicles Promote Arteriogenesis in Chronically Ischemic Myocardium in the Setting of Metabolic Syndrome by Scrimgeour, Laura A, Potz, Brittany A, Pavlov, Vasile I, Shi, Guangbin, Stanley, Melissa, Zhang, Zhiqi, Abid, M Ruhul, Sellke, Frank W

“…IntroductionIschemic heart disease continues to be a leading cause of mortality and patients with metabolic syndrome are at even higher risk. While…”
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