Search Results - "Pavlikova, Lucia"

The Roles of microRNAs in Cancer Multidrug Resistance by Pavlíková, Lucia, Šereš, Mário, Breier, Albert, Sulová, Zdena

“…Cancer chemotherapy may induce a multidrug resistance (MDR) phenotype. The development of MDR is based on various molecular causes, of which the following are…”
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Development of Resistance to Endoplasmic Reticulum Stress-Inducing Agents in Mouse Leukemic L1210 Cells by Cagala, Martin, Pavlikova, Lucia, Seres, Mario, Kadlecikova, Karolina, Breier, Albert, Sulova, Zdena

“…Four new variants of L1210 cells resistant to endoplasmic reticulum (ER) stressors, tunicamycin (S ), thapsigargin (S ), bortezomib (S ), and MG-132 (S ), were…”
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Triorganotin Derivatives Induce Cell Death Effects on L1210 Leukemia Cells at Submicromolar Concentrations Independently of P-glycoprotein Expression by Bohacova, Viera, Seres, Mario, Pavlikova, Lucia, Kontar, Szilvia, Cagala, Martin, Bobal, Pavel, Otevrel, Jan, Brtko, Julius, Sulova, Zdena, Breier, Albert

“…The acceleration of drug efflux activity realized by plasma membrane transporters in neoplastic cells, particularly by P-glycoprotein (P-gp, ABCB1 member of…”
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Screening of Phenanthroquinolizidine Alkaloid Derivatives for Inducing Cell Death of L1210 Leukemia Cells with Negative and Positive P-glycoprotein Expression by Kubíčková, Jana, Elefantová, Katarína, Pavlikova, Lucia, Cagala, Martin, Šereš, Mário, Šafář, Peter, Marchalín, Štefan, Ďurišová, Kamila, Boháčová, Viera, Sulova, Zdena, Lakatoš, Boris, Breier, Albert, Olejníková, Petra

“…We describe the screening of a set of cryptopleurine derivatives, namely thienoquinolizidine derivatives and (epi-)benzo analogs with bioactive…”
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L1210 Cells Overexpressing ABCB1 Drug Transporters Are Resistant to Inhibitors of the N- and O-glycosylation of Proteins by Pavlikova, Lucia, Seres, Mario, Hano, Milan, Bohacova, Viera, Sevcikova, Ivana, Kyca, Tomas, Breier, Albert, Sulova, Zdena

“…Overexpression of P-glycoprotein (P-gp, drug transporter) in neoplastic cells is the most frequently observed molecular cause of multidrug resistance. Here, we…”
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Reduced UDP-glucose Levels Are Associated with P-glycoprotein Over-expression in L1210 Cells and Limit Glucosylceramide Synthase Activity by Turáková, Katarina, Pavlíková, Lucia, Messingerová, Lucia, Lakatoš, Boris, Breier, Albert, Sulová, Zdena

“…P-glycoprotein (Pgp) expression in neoplastic cells is known to reduce cell sensitivity to several cytotoxic Pgp substrates. A member of the ABC transporter…”
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Interplay between P-Glycoprotein Expression and Resistance to Endoplasmic Reticulum Stressors by Hano, Milan, Tomášová, Lenka, Šereš, Mário, Pavlíková, Lucia, Breier, Albert, Sulová, Zdena

“…Multidrug resistance (MDR) is a phenotype of cancer cells with reduced sensitivity to a wide range of unrelated drugs. P-glycoprotein (P-gp)-a drug efflux pump…”
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Insight into Bortezomib Focusing on Its Efficacy against P-gp-Positive MDR Leukemia Cells by Kyca, Tomáš, Pavlíková, Lucia, Boháčová, Viera, Mišák, Anton, Poturnayová, Alexandra, Breier, Albert, Sulová, Zdena, Šereš, Mário

“…In this paper, we compared the effects of bortezomib on L1210 (S) cells with its effects on P-glycoprotein (P-gp)-positive variant S cells, which expressed…”
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Overexpression of GRP78/BiP in P-Glycoprotein-Positive L1210 Cells is Responsible for Altered Response of Cells to Tunicamycin as a Stressor of the Endoplasmic Reticulum by Šereš, Mário, Pavlíková, Lucia, Boháčová, Viera, Kyca, Tomáš, Borovská, Ivana, Lakatoš, Boris, Breier, Albert, Sulová, Zdena

“…P-glycoprotein (P-gp, ABCB1 member of the ABC (ATP-binding cassette) transporter family) localized in leukemia cell plasma membranes is known to reduce cell…”
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The expression of P-gp in leukemia cells is associated with cross-resistance to protein N-glycosylation inhibitor tunicamycin by Pavlikova, Lucia, Seres, Mario, Imrichova, Denisa, Hano, Milan, Rusnak, Andrej, Zamorova, Martina, Katrlik, Jaroslav, Breier, Albert, Sulova, Zdena

“…In P-gp-positive cell variants obtained from L1210 cells either by selection with vincristine (L1210/R) or by transfection with the human gene encoding P-gp…”
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