Search Results - "Pavelić, K"
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The novel primaquine derivatives of N-alkyl, cycloalkyl or aryl urea: Synthesis, cytostatic and antiviral activity evaluations
Published in European journal of medicinal chemistry (01-06-2008)“…The novel urea primaquine derivatives 3a– i were prepared by aminolysis of benzotriazolide 2 with the corresponding amine in the presence or absence of…”
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2
NF1 gene loss of heterozygosity and expression analysis in sporadic colon cancer
Published in Gut (01-08-2005)“…Background and aim: Colon cancer tumorigenesis is a multistep process of mutation accumulation in a number of oncogenes and tumour suppressor genes. NF1 gene…”
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3
Comparison of five different polymerase chain reaction methods for detection of human papillomavirus in cervical cell specimens
Published in Journal of virological methods (01-08-2000)“…The polymerase chain reaction (PCR) methods enable the detection of large number of human papillomavirus (HPV) genotypes that infect the anogenital tract. In…”
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4
Recent advances in molecular genetics of breast cancer
Published in Journal of molecular medicine (Berlin, Germany) (01-10-2001)“…Breast cancer is among the most common tumors affecting women. It is characterized by a number of genetic aberrations. Some 5-10% of cases are thought to be…”
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5
Synthesis and in vitro antitumor effect of diclofenac and fenoprofen thiolated and nonthiolated polyaspartamide-drug conjugates
Published in European journal of medicinal chemistry (2007)“…This paper reports the synthesis and antiproliferative effects of new thiomer–diclofenac and fenoprofen conjugates, hydrophilic, bioadhesive, polymeric…”
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6
Synthesis, crystal structure and antiproliferative evaluation of some new substituted benzothiazoles and styrylbenzothiazoles
Published in Farmaco (Società chimica italiana : 1989) (01-04-2004)“…The multistep synthesis of a series of new substituted-benzothiazoles as hydrochloride or quaternary salts is described. 6-Amidino substituted…”
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7
Is tumour suppressor gene p53 involved in neuroendocrine tumour carcinogenesis?
Published in The Journal of pathology (01-03-1996)“…I read with interest the report by Wang et al. regarding the tumour suppressor gene p53 in neuroendocrine carcinogenesis. The tumours investigated in their…”
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8
Increased activity of nm23-H1 gene in squamous cell carcinoma of the head and neck is associated with advanced disease and poor prognosis
Published in Journal of molecular medicine (Berlin, Germany) (01-01-2000)“…The present study was undertaken to determine whether the nm23-H1 gene is expressed in squamous cell carcinoma of the head and neck (SCCHN) and whether the…”
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9
Novel Pyrimidine and Purine Derivatives of l-Ascorbic Acid: Synthesis and Biological Evaluation
Published in Journal of medicinal chemistry (15-07-1999)“…The novel pyrimidine derivatives 1−6 of 2,3-dibenzyl-4,5-didehydro-5,6-dideoxy-l-ascorbic acid were synthesized by the condensation of pyrimidine bases with…”
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10
In vitro cytotoxicity of three 4,9-diazapyrenium hydrogensulfate derivatives on different human tumor cell lines
Published in Chemotherapy (Basel) (01-03-2000)“…DNA intercalating agents interfere with DNA's role as a template in replication and transcription by inserting an intercalator molecule between adjacent base…”
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11
The novel phosphoramidate derivatives of NSAID 3-hydroxypropylamides: Synthesis, cytostatic and antiviral activity evaluations
Published in European journal of medicinal chemistry (2009)“…The target phosphoramidates 5a– e were prepared in one step from 3-hydroxypropyl derivatives 3a– e of nonsteroidal anti-inflammatory drugs (fenoprofen,…”
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12
The new 5- or 6-azapyrimidine and cyanuric acid derivatives of l-ascorbic acid bearing the free C-5 hydroxy or C-4 amino group at the ethylenic spacer: CD-spectral absolute configuration determination and biological activity evaluations
Published in European journal of medicinal chemistry (01-07-2011)“…We report on the synthesis of the novel types of cytosine and 5-azacytosine ( 1– 9), uracil and 6-azauracil ( 13– 18) and cyanuric acid ( 19– 22) derivatives…”
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13
Multiple genetic alterations in malignant metastatic insulinomas
Published in The Journal of pathology (01-12-1995)“…Proto-oncogenes, growth factors/receptors, and tumour suppressor genes were analysed in malignant metastatic insulinomas. Normal pancreas showed only a…”
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14
Submerged gel electrophoresis on Spreadex gels : a new method for APC gene mutation detection
Published in Journal of molecular medicine (Berlin, Germany) (01-06-2001)“…Familial adenomatous polyposis (FAP) is an autosomal dominant inherited disease. Patients with FAP develop hundreds to thousands of adenomatous polyps in the…”
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15
Analysis of Selected Genes in Neuroendocrine Tumours: Insulinomas and Phaeochromocytomas
Published in Journal of neuroendocrinology (01-08-2008)“…Insulinomas and phaeochromocytomas are neuroendocrine tumours that may be either sporadic or manifestation of a familial cancer syndromes and are both derived…”
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16
Molecular mechanisms of anticancer activity of natural dietetic products
Published in Journal of molecular medicine (Berlin, Germany) (01-01-2000)“…The efficiency of dietetic supplements in cancer prevention and treatment is a popular and controversial subject of research. New in vitro and in vivo research…”
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17
Screening for fragile X syndrome: results from a school for mentally retarded children
Published in Acta Paediatrica (01-05-2002)“…Fragile X syndrome is the most common inherited form of familial mental retardation. The purpose of this study was to identify yet unrecognized fragile X…”
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18
Loss of heterozygosity and protein expression of APC gene in renal cell carcinomas
Published in Journal of molecular medicine (Berlin, Germany) (01-05-1999)“…This study evaluated the potential contribution of the APC gene to malignant transformation in patients with renal cell carcinoma. We tested 36 human renal…”
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19
Novel alleles of the D16S752 polymorphic genetic marker linked to E-cadherin gene--a potential population marker
Published in Collegium antropologicum (01-06-2002)“…Seven DNA variants that polymorphic genetic marker D16S752 reveals in Croatian population are reported in this paper. The marker is a GATA tetranucleotide…”
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20
PCR amplification of DNA from stained cytological smears
Published in Journal of clinical pathology (01-04-1993)“…DNA from archival Papanicolaou stained smears was successfully amplified using the polymerase chain reaction (PCR) to see if it could be used for retrospective…”
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