Search Results - "Pavel Babica"

Bile Acids Transporters of Enterohepatic Circulation for Targeted Drug Delivery by Durník, Robin, Šindlerová, Lenka, Babica, Pavel, Jurček, Ondřej

“…Bile acids (BAs) are important steroidal molecules with a rapidly growing span of applications across a variety of fields such as supramolecular chemistry,…”
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Applicability of Scrape Loading-Dye Transfer Assay for Non-Genotoxic Carcinogen Testing by Sovadinová, Iva, Upham, Brad L., Trosko, James E., Babica, Pavel

“…Dysregulation of gap junction intercellular communication (GJIC) is recognized as one of the key hallmarks for identifying non-genotoxic carcinogens (NGTxC)…”
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Improved multiparametric scrape loading-dye transfer assay for a simultaneous high-throughput analysis of gap junctional intercellular communication, cell density and viability by Dydowiczová, Aneta, Brózman, Ondřej, Babica, Pavel, Sovadinová, Iva

“…Gap junctional intercellular communication (GJIC) is a vital cellular process required for maintenance of tissue homeostasis. In vitro assessment of GJIC…”
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Different DNA damage response of cis and trans isomers of commonly used UV filter after the exposure on adult human liver stem cells and human lymphoblastoid cells by Sharma, Anežka, Bányiová, Katarína, Babica, Pavel, El Yamani, Naouale, Collins, Andrew Richard, Čupr, Pavel

“…2-ethylhexyl 4-methoxycinnamate (EHMC), used in many categories of personal care products (PCPs), is one of the most discussed ultraviolet filters because of…”
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Structure-Dependent Effects of Phthalates on Intercellular and Intracellular Communication in Liver Oval Cells by Čtveráčková, Lucie, Jančula, Daniel, Raška, Jan, Babica, Pavel, Sovadinová, Iva

“…Humans are exposed to phthalates released from plastics, cosmetics, or food on a daily basis. Phthalates have low acute liver toxicity, but their chronic…”
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Immunomodulatory Potency of Microcystin, an Important Water-Polluting Cyanobacterial Toxin by Adamovsky, Ondrej, Moosova, Zdena, Pekarova, Michaela, Basu, Amrita, Babica, Pavel, Svihalkova Sindlerova, Lenka, Kubala, Lukas, Blaha, Ludek

“…Microcystins (MCs) are primarily hepatotoxins produced by cyanobacteria and are responsible for intoxication in humans and animals. There are many incidents of…”
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Microcystin-LR Does Not Alter Cell Survival and Intracellular Signaling in Human Bronchial Epithelial Cells by Brózman, Ondřej, Kubickova, Barbara, Babica, Pavel, Laboha, Petra

“…Changes in ecological and environmental factors lead to an increased occurrence of cyanobacterial water blooms, while secondary metabolites-producing…”
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Dibenzocyclooctadiene Lignans from Schisandra chinensis with Anti-Inflammatory Effects by Rybnikář, Michal, Malaník, Milan, Šmejkal, Karel, Švajdlenka, Emil, Shpet, Polina, Babica, Pavel, Dall'Acqua, Stefano, Smištík, Ondřej, Jurček, Ondřej, Treml, Jakub

“…(Schisandraceae) is a medicinal plant widely used in traditional Chinese medicine. Under the name Wu Wei Zi, it is used to treat many diseases, especially as a…”
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Cyanobacterial Harmful Bloom Lipopolysaccharides Induce Pro-Inflammatory Effects in Immune and Intestinal Epithelial Cells In Vitro by Skočková, Veronika, Vašíček, Ondřej, Sychrová, Eliška, Sovadinová, Iva, Babica, Pavel, Šindlerová, Lenka

“…Freshwater cyanobacterial harmful blooms (CyanoHABs) produce a variety of toxic and bioactive compounds including lipopolysaccharides (LPSs). The…”
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The Origin of Teratogenic Retinoids in Cyanobacteria by Sehnal, Luděk, Smutná, Marie, Bláhová, Lucie, Babica, Pavel, Šplíchalová, Petra, Hilscherová, Klára

“…Although information about the occurrence and distribution of retinoids in the environment is scarce, cyanobacterial water blooms have been identified as a…”
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Phosphatidylcholine Specific PLC-Induced Dysregulation of Gap Junctions, a Robust Cellular Response to Environmental Toxicants, and Prevention by Resveratrol in a Rat Liver Cell Model by Sovadinova, Iva, Babica, Pavel, Böke, Hatice, Kumar, Esha, Wilke, Andrew, Park, Joon-Suk, Trosko, James E, Upham, Brad L

“…Dysregulation of gap junctional intercellular communication (GJIC) has been associated with different pathologies, including cancer; however, molecular…”
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Polycyclic aromatic hydrocarbon-induced signaling events relevant to inflammation and tumorigenesis in lung cells are dependent on molecular structure by Osgood, Ross S, Upham, Brad L, Hill, 3rd, Thomas, Helms, Katherine L, Velmurugan, Kalpana, Babica, Pavel, Bauer, Alison K

“…Polycyclic aromatic hydrocarbons (PAHs) are ubiquitous environmental and occupational toxicants, which are a major human health concern in the U.S. and abroad…”
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Chemopreventive Agents Attenuate Rapid Inhibition of Gap Junctional Intercellular Communication Induced by Environmental Toxicants by Babica, Pavel, Čtveráčková, Lucie, Lenčešová, Zuzana, Trosko, James E., Upham, Brad L.

“…Altered gap junctional intercellular communication (GJIC) has been associated with chemical carcinogenesis, where both chemical tumor promoters and…”
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Synthetic Biomimetic Polymethacrylates: Promising Platform for the Design of Anti-Cyanobacterial and Anti-Algal Agents by Mikula, Přemysl, Mlnaříková, Marie, Nadres, Enrico T, Takahashi, Haruko, Babica, Pavel, Kuroda, Kenichi, Bláha, Luděk, Sovadinová, Iva

“…Extensive, uncontrolled growth of algae and cyanobacteria is an environmental, public health, economic, and technical issue in managing natural and engineered…”
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Lipopolysaccharides from Microcystis Cyanobacteria-Dominated Water Bloom and from Laboratory Cultures Trigger Human Immune Innate Response by Moosová, Zdena, Šindlerová, Lenka, Ambrůzová, Barbora, Ambrožová, Gabriela, Vašíček, Ondřej, Velki, Mirna, Babica, Pavel, Kubala, Lukáš

“…Massive toxic blooms of cyanobacteria represent a major threat to water supplies worldwide. Here, the biological activities of lipopolysaccharide (LPS)…”
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Evaluation of extraction approaches linked to ELISA and HPLC for analyses of microcystin-LR, -RR and -YR in freshwater sediments with different organic material contents by Babica, Pavel, Kohoutek, Jiří, Bláha, Luděk, Adamovský, Ondřej, Maršálek, Blahoslav

“…The efficiencies of conventional extraction techniques and analytical methods (HPLC-DAD and ELISA) were investigated for analyses of microcystins (MCs) in…”
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Assessment of Chemical Impact of Invasive Bryozoan Pectinatella magnifica on the Environment: Cytotoxicity and Antimicrobial Activity of P. magnifica Extracts by Kollar, Peter, Šmejkal, Karel, Salmonová, Hana, Vlková, Eva, Lepšová-Skácelová, Olga, Balounová, Zuzana, Rajchard, Josef, Cvačka, Josef, Jaša, Libor, Babica, Pavel, Pazourek, Jiří

“…, an invasive bryozoan, might significantly affect ecosystem balance due to its massive occurrence in many areas in Europe and other parts of the world…”
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Tumor promoting properties of a cigarette smoke prevalent polycyclic aromatic hydrocarbon as indicated by the inhibition of gap junctional intercellular communication via phosphatidylcholine‐specific phospholipase C by Upham, Brad L., Bláha, Ludek, Babica, Pavel, Park, Joon‐Suk, Sovadinova, Iva, Pudrith, Charles, Rummel, Alisa M., Weis, Liliane M., Sai, Kimie, Tithof, Patti K., Gužvić, Miodrag, Vondráček, Jan, Machala, Miroslav, Trosko, James E.

“…Inhibition of gap junctional intercellular communication (GJIC) and the activation of intracellular mitogenic pathways are common hallmarks of epithelial…”
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Cyanobacteria and microcystin contamination in untreated and treated drinking water in Ghana by Addico, Gloria Naa Dzama, Hardege, Jörg D., Kohoutek, Jiri, DeGraft-Johnson, Kweku Amoaku Atta, Babica, Pavel

“…Although cyanobacterial blooms and cyanotoxins represent a worldwide-occurring phenomenon, there are large differences among different countries in…”
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Chlorination and ozonation differentially reduced the microcystin content and tumour promoting activity of a complex cyanobacterial extract by Iva Sovadinova, Pavel Babica, Ondřej Adamovský, Alla Alpatová, Volodymyr Tarabara, Brad Luther Upham, Luděk Bláha

“…Despite intensive research and management efforts in the past decades, cyanobacterial blooms and their toxins, such as microcystins (MCs), continue to…”
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