Search Results - "Pavanni, R"

Differential effect of caffeine intake in subjects with genetic susceptibility to Parkinson’s Disease by Kumar, Prakash M., Paing, Swe Swe Thet, Li, HuiHua, Pavanni, R., Yuen, Y., Zhao, Y., Tan, Eng King

“…We examined if caffeine intake has a differential effect in subjects with high and low genetic susceptibility to Parkinson’s disease (PD), a common…”
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Analysis of GWAS-linked loci in Parkinson disease reaffirms PARK16 as a susceptibility locus by TAN, E.-K, KWOK, H.-K, TODA, T, LIU, J.-J, TAN, L. C, ZHAO, W.-T, PRAKASH, K. M, AU, W.-L, PAVANNI, R, NG, Y.-Y, SATAKE, W, ZHAO, Y

“…A genome-wide association study (GWAS) in the Japanese population identified 2 new Parkinson disease (PD) susceptibility loci on 1q32 (PARK16) (OMIM 613164)…”
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The G2019S LRRK2 mutation is uncommon in an Asian cohort of Parkinson's disease patients by Tan, E.K., Shen, H., Tan, L.C.S., Farrer, M., Yew, K., Chua, E., Jamora, R.D., Puvan, K., Puong, K.Y., Zhao, Y., Pavanni, R., Wong, M.C., Yih, Yuen, Skipper, L., Liu, Jian-Jun

“…A common heterozygous leucine-rich repeat kinase 2 (LRRK2) mutation 6055G > A transition (G2019S) accounts for about 3–7% of familial Parkinson's disease (PD)…”
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The LRRK2 Gly2385Arg variant is associated with Parkinson's disease : genetic and functional evidence by TAN, E. K, ZHAO, Y, TAN, L, PAVANNI, R, WONG, M. C, KOLATKAR, P, LU, C. S, BONIFATI, V, LIU, J. J, SKIPPER, L, TAN, M. G, DI FONZO, A, SUN, L, FOOK-CHONG, S, TANG, S, CHUA, E, YUEN, Y

“…Evidence of LRRK2 haplotypes associated with Parkinson's disease (PD) risk was recently found in the Chinese population from Singapore, and a common LRRK2…”
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Dose-dependent protective effect of coffee, tea, and smoking in Parkinson's disease: a study in ethnic Chinese by Tan, E.-K., Tan, C., Fook-Chong, S.M.C., Lum, S.Y., Chai, A., Chung, H., Shen, H., Zhao, Y., Teoh, M.L., Yih, Y., Pavanni, R., Chandran, V.R., Wong, M.C.

“…Introduction: Few studies have examined the relationship of coffee and tea in Parkinson's disease (PD). The potential protective effect of coffee intake and…”
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LRRK2 R1628P increases risk of Parkinson’s disease: replication evidence by Tan, E. K., Tan, Louis C., Lim, H. Q., Li, R., Tang, M., Yih, Yuen, Pavanni, R., Prakash, K. M., Fook-Chong, S., Zhao, Yi

“…We showed that the frequency of a LRRK2 variant (c.4883G > C, R1628P) was higher in Parkinson’s disease (PD) compared to controls (8.4 vs. 3.4%, P  = 0.046, OR…”
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Complementary therapies in hemifacial spasm and comparison with other movement disorders by Peeraully, T, Hameed, S, Cheong, P T, Pavanni, R, Hussein, K, Fook-Chong, S M C, Tan, E-K

“…We determined the prevalence, range and factors influencing the use of complementary therapy among hemifacial spasm patients and compared the patterns of use…”
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1.231 SEVERITY OF HEMIFACIAL SPASM CORRELATES WITH THE USE OF COMPLEMENTARY THERAPIES by Cheong, W.T.P, Pavanni, R, Hameed, S, Hussien, K, Tan, E.K

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Analysis of LRRK2 functional domains in nondominant Parkinson disease by SKIPPER, L, SHEN, H, PAVANNI, R, WONG, M. C, YUEN, Y, FARRER, M, LIU, J. J, TAN, E. K, CHUA, E, BONNARD, C, KOLATKAR, P, TAN, L. C. S, JAMORA, R. D, PUVAN, K, PUONG, K. Y, ZHAO, Y

“…A comprehensive sequence analysis of 29 exons that code for the functional domains of LRRK2 in 160 nondominant Parkinson disease (PD) patients was performed…”
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DRD3 variant and risk of essential tremor by TAN, E.-K, PRAKASH, K. M, FOOK-CHONG, S, YIH, Y, CHUA, E, LUM, S. Y, WONG, M. C, PAVANNI, R, ZHAO, Y

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MDR1, the blood–brain barrier transporter, is associated with Parkinson’s disease in ethnic Chinese by Lee, C G L, Tang, K, Cheung, Y B, Wong, L P, Tan, C, Shen, H, Zhao, Y, Pavanni, R, Lee, E J D, Wong, M-C, Chong, S S, Tan, E K

“…Pathogenic mutations in several genes-including α-synuclein, Parkin, UCH-L1 (ubiquitin-C terminal hydrolase-L1) and DJ-1-have previously been identified in…”
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Alpha-synuclein haplotypes implicated in risk of Parkinson's disease by TAN, E. K, CHAI, A, WONG, M. C, PUVAN, K, LO, Y. L, YAP, E, TEO, Y. Y, ZHAO, Y, TAN, C, SHEN, H, CHANDRAN, V. R, TEOH, M. L, YIH, Y, PAVANNI, R

“…The authors examined four- and six-loci haplotype constructs (from five single nucleotide polymorphisms and three microsatellite regions) of the…”
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Fragile X premutation alleles in SCA, ET, and parkinsonism in an Asian cohort by TAN, E. K, ZHAO, Y, YIH, Y, PAVANNI, R, WONG, M. C, NG, I. S, PUONG, K. Y, LAW, H. Y, CHAN, L. L, YEW, K, TAN, C, SHEN, H, CHANDRAN, V. R, TEOH, M. L

“…Among 367 subjects, the authors analyzed 167 patients with essential tremor, sporadic progressive cerebellar ataxia, multiple-system atrophy, and atypical…”
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Impaired transcriptional upregulation of Parkin promoter variant under oxidative stress and proteasomal inhibition : clinical association by TAN, E. K, PUONG, K. Y, WONG, M. C, PUVAN, K, ZHAO, Y, CHAN, D. K. Y, YEW, K, FOOK-CHONG, S, SHEN, H, NG, P. W, WOO, J, YUEN, Y, PAVANNI, R

“…We provided data to show that the transcriptional activity of wildtype -258T in the parkin promoter region was significantly higher than the -258G variant in…”
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Genetic analysis of SCA2, 3 and 17 in idiopathic Parkinson's disease by Lim, S.W., Zhao, Y., Chua, E., Law, H.Y., Yuen, Y., Pavanni, R., Wong, M.C., Ng, I.S., Yoon, C.S., Puong, K.Y., Lim, S.H., Tan, E.K.

“…Recent reports of SCA2 and SCA3 patients who presented with levodopa responsive parkinsonism have generated considerable interest as they have implications for…”
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P3.040 Non synonymous GIGYF2 variants in Parkinson's disease by Prakash, K.M, Lim, H.Q, Lee, R, Pavanni, R, Tan, L, Tan, E.K

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Prescribing pattern in Parkinson's disease: are cost and efficacy overriding factors? by Tan, E K, Yeo, A P, Tan, V, Pavanni, R, Wong, M C

“…Information on prescribing pattern of antiparkinsonian medications and factors influencing neurologists' choice of such drugs are important considerations in…”
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Is hypertension associated with hemifacial spasm? by TAN, E. K, CHAN, L. L, LUM, S. Y, KOH, P, HAN, S. Y, FOOK-CHONG, S. M. C, LO, Y. L, PAVANNI, R, WONG, M. C, LIM, S. H

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Differential expression of splice variant and wild-type parkin in sporadic Parkinson's disease by TAN, E. K, SHEN, H, YUEN, Y, PAVANNI, R, WONG, M. C, PUVAN, K, ZHAO, Y, TAN, J. M. M, LIM, K. L, FOOK-CHONG, S, HU, W. P, PATERSON, M. C, CHANDRAN, V. R, YEW, K, TAN, C

“…Altered splicing of parkin under cellular stress could lead to changes in gene expression and altered protein activity. The causative role of parkin in…”
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Analysis of PINK1 in Asian patients with familial parkinsonism by Tan, EK, Yew, K, Chua, E, Shen, H, Jamora, RD, Lee, E, Puong, KY, Zhao, Y, Pavanni, R, Wong, MC, Puvan, K, Yih, Y, Tan, LCS

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