Search Results - "Pavan, Isadora C. B."
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Knockout of NRF2 triggers prostate cancer cells death through ROS modulation and sensitizes to cisplatin
Published in Journal of cellular biochemistry (01-12-2022)“…Prostate cancer (PCa) represents the second most common cancer in men and affects millions worldwide. Chemotherapy is a common treatment for PCa but the…”
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2
S6Ks isoforms contribute to viability, migration, docetaxel resistance and tumor formation of prostate cancer cells
Published in BMC cancer (05-08-2016)“…The S6 Kinase (S6K) proteins are some of the main downstream effectors of the mammalian Target Of Rapamycin (mTOR) and act as key regulators of protein…”
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Different interactomes for p70-S6K1 and p54-S6K2 revealed by proteomic analysis
Published in Proteomics (Weinheim) (01-10-2016)“…S6Ks are major effectors of the mTOR (mammalian target of rapamycin) pathway, signaling for increased protein synthesis and cell growth in response to insulin,…”
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The S6K protein family in health and disease
Published in Life sciences (1973) (15-06-2015)“…The S6K proteins are mTOR pathway effectors and accumulative evidence suggest that mTOR/S6K signaling contributes to several pathological conditions, such as…”
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Taurine upregulates insulin signaling and mitochondrial metabolism in vitro but not in adipocytes of obese women
Published in Nutrition (Burbank, Los Angeles County, Calif.) (01-01-2022)“…•Taurine is associated with insulin signaling and mitochondrial metabolism in mice.•Taurine doses modulated taurine synthesis and AMP-activated protein kinase…”
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Aging reduces ABHD5 protein content in the adipose tissue of mice: The reversal effect of exercise
Published in Cell biochemistry and function (01-01-2023)“…Dysfunction of the adipose tissue metabolism is considered as a significant hallmark of aging. It has been proposed that α‐β hydrolase domain containing 5…”
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p53 and metabolism: from mechanism to therapeutics
Published in Oncotarget (04-05-2018)“…The tumor cell changes itself and its microenvironment to adapt to different situations, including action of drugs and other agents targeting tumor control…”
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Correction: p53 and metabolism: from mechanism to therapeutics
Published in Oncotarget (21-09-2018)“…[This corrects the article DOI: 10.18632/oncotarget.25267.]…”
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