Search Results - "Pautz, Andrea"

Regulation of NOS expression in vascular diseases by Pautz, Andrea, Li, Huige, Kleinert, Hartmut

“…Nitric oxide synthases (NOS) are the major sources of nitric oxide (NO), a small bioactive molecule involved in the regulation of many cellular processes. One…”
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Regulation of the expression of inducible nitric oxide synthase by Pautz, Andrea, Art, Julia, Hahn, Susanne, Nowag, Sebastian, Voss, Cornelia, Kleinert, Hartmut

“…Nitric oxide (NO) generated by the inducible isoform of nitric oxide synthase (iNOS) is involved in complex immunomodulatory and antitumoral mechanisms and has…”
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The mRNA-Binding Protein KSRP Limits the Inflammatory Response of Macrophages by Bolduan, Vanessa, Palzer, Kim-Alicia, Hieber, Christoph, Schunke, Jenny, Fichter, Michael, Schneider, Paul, Grabbe, Stephan, Pautz, Andrea, Bros, Matthias

“…KH-type splicing regulatory protein (KSRP) is a single-stranded nucleic acid-binding protein with multiple functions. It is known to bind AU-rich motifs within…”
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Sex-specific differences in SLE - Significance in the experimental setting of inflammation and kidney damage in MRL-Faslpr mice by Saurin, Sabrina, Meineck, Myriam, Claßen, Paul, Boedecker-Lips, Simone Cosima, Pautz, Andrea, Weinmann-Menke, Julia

“…Animal models are an important tool in the research of chronic autoimmune diseases, like systemic lupus erythematosus (SLE). MRL-Faslpr mice are one of…”
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Effect of the antirheumatic medication methotrexate (MTX) on biomechanical compressed human periodontal ligament fibroblasts (hPDLFs) by Welte-Jzyk, Claudia, Plümer, Vera, Schumann, Sven, Pautz, Andrea, Erbe, Christina

“…The aim of this study was to investigate the in vitro effect of the antirheumatic drug methotrexate (MTX) on biomechanically compressed human periodontal…”
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Regulation of the expression of inducible nitric oxide synthase by Kleinert, Hartmut, Pautz, Andrea, Linker, Katrin, Schwarz, Petra M.

“…The role of nitric oxide (NO) generated by the inducible isoform of nitric oxide synthase (iNOS) is very complex. Induction of iNOS expression and hence NO…”
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Drug Candidates for Autoimmune Diseases by Saurin, Sabrina, Meineck, Myriam, Erkel, Gerhard, Opatz, Till, Weinmann-Menke, Julia, Pautz, Andrea

“…Most of the immunosuppressive drugs used in the clinic to prevent organ rejection or to treat autoimmune disorders were originally isolated from fungi or…”
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The macrocyclic lactone oxacyclododecindione reduces fibrosis progression by Saurin, Sabrina, Meineck, Myriam, Rohr, Markus, Roth, Wilfried, Opatz, Till, Erkel, Gerhard, Pautz, Andrea, Weinmann-Menke, Julia

“…Renal fibrosis is one of the most important triggers of chronic kidney disease (CKD), and only a very limited number of therapeutic options are available to…”
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The Role of KH-Type Splicing Regulatory Protein (KSRP) for Immune Functions and Tumorigenesis by Palzer, Kim-Alicia, Bolduan, Vanessa, Käfer, Rudolf, Kleinert, Hartmut, Bros, Matthias, Pautz, Andrea

“…Post-transcriptional control of gene expression is one important mechanism that enables stringent and rapid modulation of cytokine, chemokines or growth…”
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P103 14-Deoxy-14-methyloxacyclododecindione: a new therapeutic approach of SLE? by Saurin, Sabrina, Meineck, Myriam, Opatz, Till, Erkel, Gerhard, Pautz, Andrea, Weinmann-Menke, Julia

“…ObjectiveSystemic lupus erythematosus (SLE) is a systemic chronic autoimmune disease characterized by dysregulation of immune system. Increased immune cell…”
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A specific, non-immune system-related isoform of the human inducible nitric oxide synthase is expressed during differentiation of human stem cells into various cell types by Gather, Fabian, Ihrig-Biedert, Irmgard, Kohlhas, Paul, Krutenko, Tamara, Peitz, Michael, Brüstle, Oliver, Pautz, Andrea, Kleinert, Hartmut

“…NOS2 expression is mostly found in bacteria-exposed or cytokine-treated tissues and is mostly connected to innate immune reactions. There are three isoforms of…”
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Artichoke, cynarin and cyanidin downregulate the expression of inducible nitric oxide synthase in human coronary smooth muscle cells by Xia, Ning, Pautz, Andrea, Wollscheid, Ursula, Reifenberg, Gisela, Förstermann, Ulrich, Li, Huige

“…Artichoke (Cynara scolymus L.) is one of the world's oldest medicinal plants with multiple health benefits. We have previously shown that artichoke leaf…”
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A comparison of urinary bladder weight in male and female mice across five models of diabetes and obesity by Erdogan, Betül R, Michel, Martina B, Matthes, Jan, Castañeda, Tamara R, Christen, Urs, Arioglu-Inan, Ebru, Michel, Martin C, Pautz, Andrea

“…Diabetes often leads to lower urinary tract dysfunction. The most frequently assessed parameter of urinary bladder dysfunction in animal models of diabetes is…”
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Resveratrol post-transcriptionally regulates pro-inflammatory gene expression via regulation of KSRP RNA binding activity by Bollmann, Franziska, Art, Julia, Henke, Jenny, Schrick, Katharina, Besche, Verena, Bros, Matthias, Li, Huige, Siuda, Daniel, Handler, Norbert, Bauer, Florian, Erker, Thomas, Behnke, Felix, Mönch, Bettina, Härdle, Lorena, Hoffmann, Markus, Chen, Ching-Yi, Förstermann, Ulrich, Dirsch, Verena M, Werz, Oliver, Kleinert, Hartmut, Pautz, Andrea

“…Resveratrol shows beneficial effects in inflammation-based diseases like cancer, cardiovascular and chronic inflammatory diseases. Therefore, the molecular…”
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P89 IL-28 as potential therapeutic target for LN by Meineck, Myriam, Kommer, Andreas, Linsel, Sebastian, Saurin, Sabrina, Möckel, Tamara, Pautz, Andrea, Schwarting, Andreas, Weinmann-Menke, Julia

“…ObjectiveLupus nephritis (LN) is a common and severe manifestation of the autoimmune disease systemic lupus erythematosus (SLE). Since LN-flares result in…”
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Analysis of 16 studies in nine rodent models does not support the hypothesis that diabetic polyuria is a main reason of urinary bladder enlargement by Yesilyurt, Zeynep E., Matthes, Jan, Hintermann, Edith, Castañeda, Tamara R., Elvert, Ralf, Beltran-Ornelas, Jesus H., Silva-Velasco, Diana L., Xia, Ning, Kannt, Aimo, Christen, Urs, Centurión, David, Li, Huige, Pautz, Andrea, Arioglu-Inan, Ebru, Michel, Martin C.

“…The urinary bladder is markedly enlarged in the type 1 diabetes mellitus model of streptozotocin-injected rats, which may contribute to the frequent diabetic…”
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The RNA-Binding Protein KSRP Modulates Cytokine Expression of CD4+ T Cells by Pautz, Andrea, Bros, Matthias, Montermann, Evelyn, Schrick, Katharina, Schmidtke, Lisa, Käfer, Rudolf, Kleinert, Hartmut

“…The KH-type splicing regulatory protein (KSRP) is a RNA-binding protein, which regulates the stability of many mRNAs encoding immune-relevant proteins. As KSRP…”
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Inactivation of the KSRP gene modifies collagen antibody induced arthritis by Käfer, Rudolf, Schrick, Katharina, Schmidtke, Lisa, Montermann, Evelyn, Hobernik, Dominika, Bros, Matthias, Chen, Ching-Yi, Kleinert, Hartmut, Pautz, Andrea

“…The KH type splicing regulatory protein (KSRP) is a nucleic acid binding protein, which negatively regulates the stability and/or translatability of many mRNA…”
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Transcriptional and post-transcriptional regulation of iNOS expression in human chondrocytes by Schmidt, Nadine, Pautz, Andrea, Art, Julia, Rauschkolb, Peter, Jung, Matthias, Erkel, Gerhard, Goldring, Mary B., Kleinert, Hartmut

“…Chondrocytes are important for the development and maintenance of articular cartilage. However, both in osteoarthritis (OA) and rheumatoid arthritis (RA)…”
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Tristetraprolin regulation of interleukin-22 production by Härdle, Lorena, Bachmann, Malte, Bollmann, Franziska, Pautz, Andrea, Schmid, Tobias, Eberhardt, Wolfgang, Kleinert, Hartmut, Pfeilschifter, Josef, Mühl, Heiko

“…Interleukin (IL)-22 is a STAT3-activating cytokine displaying characteristic AU-rich elements (ARE) in the 3′-untranslated region (3′-UTR) of its mRNA. This…”
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