Search Results - "Paulzen, Michael"

Therapeutic Reference Range for Aripiprazole in Schizophrenia Revised: a Systematic Review and Metaanalysis by Hart, Xenia M., Hiemke, Christoph, Eichentopf, Luzie, Lense, Xenija M., Clement, Hans Willi, Conca, Andreas, Faltraco, Frank, Florio, Vincenzo, Grüner, Jessica, Havemann-Reinecke, Ursula, Molden, Espen, Paulzen, Michael, Schoretsanitis, Georgios, Riemer, Thomas G., Gründer, Gerhard

“…Rationale While one of the basic axioms of pharmacology postulates that there is a relationship between the concentration and effects of a drug, the value of…”
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Functional connectivity signatures of NMDAR dysfunction in schizophrenia—integrating findings from imaging genetics and pharmaco-fMRI by Gaebler, Arnim J., Fakour, Nilüfer, Stöhr, Felix, Zweerings, Jana, Taebi, Arezoo, Suslova, Mariia, Dukart, Juergen, Hipp, Joerg F., Adhikari, Bhim M., Kochunov, Peter, Muthukumaraswamy, Suresh D., Forsyth, Anna, Eggermann, Thomas, Kraft, Florian, Kurth, Ingo, Paulzen, Michael, Gründer, Gerhard, Schneider, Frank, Mathiak, Klaus

“…Both, pharmacological and genome-wide association studies suggest N-methyl-D-aspartate receptor (NMDAR) dysfunction and excitatory/inhibitory (E/I)-imbalance…”
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Lower sertraline plasma concentration in patients co‐medicated with clozapine—Implications for pharmacological augmentation strategies in schizophrenia by Gaebler, Arnim Johannes, Haen, Ekkehard, Omar, Nagia Ben, Endres, Katharina, Hiemke, Christoph, Schoretsanitis, Georgios, Paulzen, Michael

“…Augmentation of antipsychotic treatment with antidepressants represents a common and beneficial treatment strategy in patients suffering from schizophrenia…”
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Plasma Risperidone-related Measures in Children and Adolescents with Oppositional Defiant/Conduct Disorders by Piacentino, Daria, Kotzalidis, Georgios D, Schoretsanitis, Georgios, Paulzen, Michael, Haen, Ekkehard, Cappelletti, Simone, Giupponi, Giancarlo, Grözinger, Michael, Conca, Andreas

“…Therapeutic drug monitoring helps clinicians in choosing the right drug and adjust its dose in specific patients. To this end, we aimed to assess time patterns…”
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Psychopharmacotherapy during pregnancy and breastfeeding-Part I: focus on pregnancy : Support options by using therapeutic drug monitoring by Paulzen, Michael, Schoretsanitis, Georgios

“…The medicinal treatment of mental disorders during pregnancy and lactation requires special knowledge about possible effects of the psychopharmacotherapy on…”
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Psychopharmacotherapy during pregnancy and breastfeeding-Part II: focus on breastfeeding : Support options by using therapeutic drug monitoring by Paulzen, Michael, Schoretsanitis, Georgios

“…The drug treatment of mental disorders during lactation requires special knowledge about the possible effects on the breastfed infant. The first part of this…”
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Pharmacokinetic Drug-Drug Interactions of Mood Stabilizers and Risperidone in Patients Under Combined Treatment by Schoretsanitis, Georgios, Haen, Ekkehard, Gründer, Gerhard, Stegmann, Benedikt, Schruers, Koen R J, Hiemke, Christoph, Lammertz, Sarah E, Paulzen, Michael

“…The combination of anticonvulsant mood stabilizers with antipsychotic drugs may lead to clinically relevant drug-drug interactions. The objective of the study…”
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Elevated Clozapine Concentrations in Clozapine-Treated Patients with Hypersalivation by Schoretsanitis, Georgios, Kuzin, Maxim, Kane, John M., Hiemke, Christoph, Paulzen, Michael, Haen, Ekkehard

“…Background and Objective Hypersalivation is a common, clozapine-related adverse drug reaction with a serious impact on quality of life. Pharmacokinetic…”
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Interaction Between Risperidone, Venlafaxine, and Metronidazole: An Unknown Thread by Hovancakova, Jana, Schoretsanitis, Georgios, Grözinger, Michael, Gründer, Gerhard, Paulzen, Michael

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Discovering interactions in polypharmacy: Impact of metamizole on the metabolism of quetiapine by Watermeyer, Fabian, Gaebler, Arnim Johannes, Neuner, Irene, Haen, Ekkehard, Hiemke, Christoph, Schoretsanitis, Georgios, Paulzen, Michael

“…Aims: Metamizole is quite an old drug with analgesic, antipyretic and spasmolytic properties. Recent findings have shown that it may induce several cytochrome…”
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Effect of fluvoxamine augmentation and smoking on clozapine serum concentrations by Augustin, Marc, Schoretsanitis, Georgios, Pfeifer, Philippe, Gründer, Gerhard, Liebe, Claus, Paulzen, Michael

“…Clozapine (CLZ) is metabolized via cytochrome P450 CYP1A2 to N-desmethylclozapine (NCLZ). Smoking induces CYP1A2 thereby increasing clozapine metabolism…”
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Nifedipine May Be an Inhibitor of Clozapine Metabolism, as Seen in 5 Patients: 2 from a US Double-Blind Study and 3 from a German TDM Study by Schoretsanitis, Georgios, Haen, Ekkehard, Verdoux, Hélène, Paulzen, Michael, de Leon, Jose

“…Background: Clozapine is the only licensed antipsychotic for treatment-refractory schizophrenia. Therapeutic drug monitoring (TDM) refers to the measurement of…”
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Psychopharmakotherapie in der Schwangerschaft und Stillzeit – Teil II: Schwerpunkt Stillzeit: Möglichkeiten der Unterstützung durch therapeutisches Drug-Monitoring by Paulzen, Michael, Schoretsanitis, Georgios

“…Zusammenfassung Die medikamentöse Therapie psychischer Störungen in der Stillzeit erfordert besondere Kenntnisse über mögliche Auswirkungen auf den gestillten…”
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Psychopharmakotherapie in Schwangerschaft und Stillzeit – Teil I: Schwerpunkt Schwangerschaft: Möglichkeiten der Unterstützung durch therapeutisches Drug-Monitoring by Paulzen, Michael, Schoretsanitis, Georgios

“…Zusammenfassung Die medikamentöse Therapie psychischer Störungen in der Schwangerschaft und Stillzeit erfordert besondere Kenntnisse über mögliche Auswirkungen…”
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Metamizole but not ibuprofen reduces the plasma concentration of sertraline: Implications for the concurrent treatment of pain and depression/anxiety disorders by Gaebler, Arnim Johannes, Schoretsanitis, Georgios, Ben Omar, Nagia, Haen, Ekkehard, Endres, Katharina, Hiemke, Christoph, Paulzen, Michael

“…Aim Comorbidity of pain and depression or anxiety is a challenging clinical phenomenon, often requiring the concurrent application of antidepressant and…”
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How to Treat Hypertension in Venlafaxine-Medicated Patients-Pharmacokinetic Considerations in Prescribing Amlodipine and Ramipril by Augustin, Marc, Schoretsanitis, Georgios, Gründer, Gerhard, Haen, Ekkehard, Paulzen, Michael

“…Amlodipine (AMLO) and ramipril (RAMI) belong to the most prescribed drugs in patients with hypertension, a condition also encountered in depression…”
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Discovering interactions in augmentation strategies: Impact of duloxetine on the metabolism of aripiprazole by Margraff, Teresa, Schoretsanitis, Georgios, Neuner, Irene, Haen, Ekkehard, Gaebler, Arnim Johannes, Paulzen, Michael

“…Objective We aimed to unravel potential pharmacokinetic interactions between aripiprazole and duloxetine. Methods Plasma concentrations of aripiprazole in two…”
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Antidepressants in breast milk; comparative analysis of excretion ratios by Schoretsanitis, Georgios, Augustin, Marc, Saßmannshausen, Helena, Franz, Cordula, Gründer, Gerhard, Paulzen, Michael

“…Despite increasing prescription rates of antidepressants in pregnant and breastfeeding women over the past decades, evidence of drug exposure for neonates…”
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Differences in Duloxetine Dosing Strategies in Smoking and Nonsmoking Patients: Therapeutic Drug Monitoring Uncovers the Impact on Drug Metabolism by Augustin, Marc, Schoretsanitis, Georgios, Hiemke, Christoph, Gründer, Gerhard, Haen, Ekkehard, Paulzen, Michael

“…For certain psychotropic drugs, such as clozapine or olanzapine, the influence of smoking on drug metabolism is well studied. Tobacco smoke increases the…”
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Influence of Kidney Function on Serum Risperidone Concentrations in Patients Treated With Risperidone by Gründer, Philipp, Augustin, Marc, Paulzen, Michael, Gründer, Gerhard

“…Risperidone is one of the most commonly prescribed antipsychotics worldwide. Its main metabolite, 9-hydroxyrisperidone (9-OH-RIS), is excreted renally. The…”
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