Search Results - "Paulus, Jessica"

The Predictive Approaches to Treatment effect Heterogeneity (PATH) Statement by Kent, David M, Paulus, Jessica K, van Klaveren, David, D'Agostino, Ralph, Goodman, Steve, Hayward, Rodney, Ioannidis, John P A, Patrick-Lake, Bray, Morton, Sally, Pencina, Michael, Raman, Gowri, Ross, Joseph S, Selker, Harry P, Varadhan, Ravi, Vickers, Andrew, Wong, John B, Steyerberg, Ewout W

“…Heterogeneity of treatment effect (HTE) refers to the nonrandom variation in the magnitude or direction of a treatment effect across levels of a covariate, as…”
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Predictably unequal: understanding and addressing concerns that algorithmic clinical prediction may increase health disparities by Paulus, Jessica K., Kent, David M.

“…The machine learning community has become alert to the ways that predictive algorithms can inadvertently introduce unfairness in decision-making. Herein, we…”
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Association of Episodic Physical and Sexual Activity With Triggering of Acute Cardiac Events: Systematic Review and Meta-analysis by Dahabreh, Issa J, Paulus, Jessica K

“…CONTEXT Evidence has suggested that physical and sexual activity might be triggers of acute cardiac events. OBJECTIVE To assess the effect of episodic physical…”
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The Predictive Approaches to Treatment effect Heterogeneity (PATH) Statement: Explanation and Elaboration by Kent, David M, van Klaveren, David, Paulus, Jessica K, D'Agostino, Ralph, Goodman, Steve, Hayward, Rodney, Ioannidis, John P A, Patrick-Lake, Bray, Morton, Sally, Pencina, Michael, Raman, Gowri, Ross, Joseph S, Selker, Harry P, Varadhan, Ravi, Vickers, Andrew, Wong, John B, Steyerberg, Ewout W

“…The PATH (Predictive Approaches to Treatment effect Heterogeneity) Statement was developed to promote the conduct of, and provide guidance for, predictive…”
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Predictive approaches to heterogeneous treatment effects: a scoping review by Rekkas, Alexandros, Paulus, Jessica K, Raman, Gowri, Wong, John B, Steyerberg, Ewout W, Rijnbeek, Peter R, Kent, David M, van Klaveren, David

“…Recent evidence suggests that there is often substantial variation in the benefits and harms across a trial population. We aimed to identify regression…”
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More than half of patients with a rheumatic disease or immunologic condition undergoing methotrexate treatment reside in states in which the overturning of Roe v. Wade can jeopardize access to medications with abortifacient potential by Starzyk, Kathryn, Hoffman, Veena, Su, Zhaohui, Meng, Roger, Bhartia, Mudit, Curhan, Gary, Yoshida, Kazuki, Paulus, Jessica K.

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Reduced levels of miRNAs 449 and 34 in sperm of mice and men exposed to early life stress by Dickson, David A., Paulus, Jessica K., Mensah, Virginia, Lem, Janis, Saavedra-Rodriguez, Lorena, Gentry, Adrienne, Pagidas, Kelly, Feig, Larry A.

“…Exposure of male mice to early life stress alters the levels of specific sperm miRNAs that promote stress-associated behaviors in their offspring. To begin to…”
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Mammographic Screening in Routine Practice: Multisite Study of Digital Breast Tomosynthesis and Digital Mammography Screenings by Conant, Emily F, Talley, Melinda M, Parghi, Chirag R, Sheh, Bryant C, Liang, Su-Ying, Pohlman, Scott, Rane, Amey, Jung, Yoojin, Stevens, Lauren A S, Paulus, Jessica K, Alsheik, Nila

“…Background The use of digital breast tomosynthesis (DBT) is increasing over digital mammography (DM) following studies demonstrating lower recall rates (RRs)…”
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Mocetinostat for relapsed classical Hodgkin's lymphoma: an open-label, single-arm, phase 2 trial by Younes, Anas, Prof, Oki, Yasuhiro, MD, Bociek, R Gregory, MD, Kuruvilla, John, MD, Fanale, Michelle, MD, Neelapu, Sattva, MD, Copeland, Amanda, RN, Buglio, Daniela, MD, Galal, Ahmed, MD, Besterman, Jeffrey, PhD, Li, Zuomei, PhD, Drouin, Michel, MD, Patterson, Tracy, RN, Ward, M Renee, MD, Paulus, Jessica K, ScD, Ji, Yuan, PhD, Medeiros, L Jeffrey, Prof, Martell, Robert E, MD

“…Summary Background The prognosis of patients with relapsed Hodgkin's lymphoma, especially those who relapse after stem-cell transplantation, is poor, and the…”
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Low-Osmolar Diet and Adjusted Water Intake for Vasopressin Reduction in Autosomal Dominant Polycystic Kidney Disease: A Pilot Randomized Controlled Trial by Amro, Osama W., MD, MS, Paulus, Jessica K., ScD, Noubary, Farzad, PhD, Perrone, Ronald D., MD

“…Background Autosomal dominant polycystic kidney disease (ADPKD) affects millions of people worldwide. Vasopressin promotes disease progression. Study Design A…”
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Pulmonary Arterial Capacitance Is an Important Predictor of Mortality in Heart Failure With a Preserved Ejection Fraction by Al-Naamani, Nadine, MD, Preston, Ioana R., MD, Paulus, Jessica K., ScD, Hill, Nicholas S., MD, Roberts, Kari E., MD

“…Abstract Objectives The purpose of this study was to determine the predictors of mortality in patients with pulmonary hypertension (PH) associated with heart…”
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Association Between Lymphopenia at 1 Month Posttransplant and Infectious Outcomes or Death in Heart Transplant Recipients by Perry, Whitney A, Paulus, Jessica K, Price, Lori Lyn, Snydman, David R, Chow, Jennifer K

“…Abstract Background Cell-mediated immunity is a specific target of several medications used to prevent or treat rejection in orthotopic heart transplantation…”
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Prediction Model for 30-Day Hospital Readmissions Among Patients Discharged Receiving Outpatient Parenteral Antibiotic Therapy by Allison, Genève M., Muldoon, Eavan G., Kent, David M., Paulus, Jessica K., Ruthazer, Robin, Ren, Aretha, Snydman, David R.

“…Background. Factors associated with readmission for patients prescribed outpatient parenteral antibiotic therapy (OPAT) at hospital discharge have not been…”
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Can We Trust Observational Studies Using Propensity Scores in the Critical Care Literature? A Systematic Comparison With Randomized Clinical Trials by Kitsios, Georgios D, Dahabreh, Issa J, Callahan, Sean, Paulus, Jessica K, Campagna, Anthony C, Dargin, James M

“…OBJECTIVE:To assess the degree of agreement between propensity score studies and randomized clinical trials in critical care research. DATA SOURCES:Propensity…”
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Large-scale validation of the prediction model risk of bias assessment Tool (PROBAST) using a short form: high risk of bias models show poorer discrimination by Venema, Esmee, Wessler, Benjamin S., Paulus, Jessica K., Salah, Rehab, Raman, Gowri, Leung, Lester Y., Koethe, Benjamin C., Nelson, Jason, Park, Jinny G., van Klaveren, David, Steyerberg, Ewout W., Kent, David M.

“…•High risk of bias is pervasive among published clinical prediction models.•High risk of bias identified with PROBAST is associated with poorer discriminative…”
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Surgical Predictive Model for Breast Cancer Patients Assessing Acute Postoperative Complications: The Breast Cancer Surgery Risk Calculator by Jonczyk, Michael M., Fisher, Carla Suzanne, Babbitt, Russell, Paulus, Jessica K., Freund, Karen M., Czerniecki, Brian, Margenthaler, Julie A., Losken, Albert, Chatterjee, Abhishek

“…Background Prognostic tools, such as risk calculators, improve the patient–physician informed decision-making process. These tools are limited for breast…”
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Do observational studies using propensity score methods agree with randomized trials? A systematic comparison of studies on acute coronary syndromes by DAHABREH, Issa J, SHELDRICK, Radley C, PAULUS, Jessica K, CHUNG, Mei, VARVARIGOU, Vasileia, JAFRI, Haseeb, RASSEN, Jeremy A, TRIKALINOS, Thomas A, KITSIOS, Georgios D

“…Randomized controlled trials (RCTs) are the gold standard for assessing the efficacy of therapeutic interventions because randomization protects from biases…”
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Race and Ethnicity: A Part of the Equation for Personalized Clinical Decision Making? by Paulus, Jessica K, Kent, David M

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Qualitative and quantitative variations in liver function thresholds among clinical trials in cancer: a need for harmonization by Wang, Edwin, Song, Fei, Paulus, Jessica K., Hackenyos, Douglas, Mathew, Paul

“…Purpose The liver is critically involved in drug metabolism pathways and the potential for hepatic toxicity is significant with specific cancer therapeutics…”
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External Validations of Cardiovascular Clinical Prediction Models: A Large-Scale Review of the Literature by Wessler, Benjamin S., Nelson, Jason, Park, Jinny G., McGinnes, Hannah, Gulati, Gaurav, Brazil, Riley, Van Calster, Ben, van Klaveren, David, Venema, Esmee, Steyerberg, Ewout, Paulus, Jessica K., Kent, David M.

“…Background: There are many clinical prediction models (CPMs) available to inform treatment decisions for patients with cardiovascular disease. However, the…”
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