Search Results - "Paululat, Achim"

On the Morphology of the Drosophila Heart by Rotstein, Barbara, Paululat, Achim

“…The circulatory system of represents an easily amenable genetic model whose analysis at different levels, , from single molecules up to functional anatomy, has…”
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The septate junction protein Mesh is required for epithelial morphogenesis, ion transport, and paracellular permeability in the Drosophila Malpighian tubule by Jonusaite, Sima, Beyenbach, Klaus W, Meyer, Heiko, Paululat, Achim, Izumi, Yasushi, Furuse, Mikio, Rodan, Aylin R

“…Septate junctions (SJs) are occluding cell-cell junctions that have roles in paracellular permeability and barrier function in the epithelia of invertebrates…”
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APC/CFzr regulates cardiac and myoblast cell numbers, and plays a crucial role during myoblast fusion by Drechsler, Maik, Meyer, Heiko, Wilmes, Ariane C., Paululat, Achim

“…ABSTRACT Somatic muscles are formed by the iterative fusion of myoblasts into muscle fibres. This process is driven by the recurrent recruitment of proteins to…”
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Interplay between SERCA, 4E-BP, and eIF4E in the Drosophila heart by Santalla, Manuela, García, Alejandra, Mattiazzi, Alicia, Valverde, Carlos A, Schiemann, Ronja, Paululat, Achim, Hernández, Greco, Meyer, Heiko, Ferrero, Paola

“…Appropriate cardiac performance depends on a tightly controlled handling of Ca2+ in a broad range of species, from invertebrates to mammals. The role of the…”
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Neprilysins regulate muscle contraction and heart function via cleavage of SERCA-inhibitory micropeptides by Schiemann, Ronja, Buhr, Annika, Cordes, Eva, Walter, Stefan, Heinisch, Jürgen J., Ferrero, Paola, Milting, Hendrik, Paululat, Achim, Meyer, Heiko

“…Muscle contraction depends on strictly controlled Ca 2+ transients within myocytes. A major player maintaining these transients is the sarcoplasmic/endoplasmic…”
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Formation and function of intracardiac valve cells in the Drosophila heart by Lammers, Kay, Abeln, Bettina, Hüsken, Mirko, Lehmacher, Christine, Psathaki, Olympia Ekaterini, Alcorta, Esther, Meyer, Heiko, Paululat, Achim

“…harbours a simple tubular heart that ensures haemolymph circulation within the body. The heart is built by a few different cell types, including cardiomyocytes…”
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The conserved ADAMTS-like protein lonely heart mediates matrix formation and cardiac tissue integrity by Drechsler, Maik, Schmidt, Ariane C, Meyer, Heiko, Paululat, Achim

“…Here we report on the identification and functional characterization of the ADAMTS-like homolog lonely heart (loh) in Drosophila melanogaster. Loh displays all…”
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Klf15 Is Critical for the Development and Differentiation of Drosophila Nephrocytes by Ivy, Jessica R, Drechsler, Maik, Catterson, James H, Bodmer, Rolf, Ocorr, Karen, Paululat, Achim, Hartley, Paul S

“…Insect nephrocytes are highly endocytic scavenger cells that represent the only invertebrate model for the study of human kidney podocytes. Despite their…”
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SERCA is critical to control the Bowditch effect in the heart by Balcazar, Darío, Regge, Victoria, Santalla, Manuela, Meyer, Heiko, Paululat, Achim, Mattiazzi, Alicia, Ferrero, Paola

“…The Bowditch effect or staircase phenomenon is the increment or reduction of contractile force when heart rate increases, defined as either a positive or…”
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Ammonia excretion in the marine polychaete Eurythoe complanata (Annelida) by Thiel, Daniel, Hugenschütt, Maja, Meyer, Heiko, Paululat, Achim, Quijada-Rodriguez, Alex R, Purschke, Günter, Weihrauch, Dirk

“…Ammonia is a toxic waste product from protein metabolism and needs to be either converted into less toxic molecules or, in the case of fish and aquatic…”
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Biosynthesis and assembly of the Collagen IV-like protein Pericardin in Drosophila melanogaster by Wilmes, Ariane C, Klinke, Nora, Rotstein, Barbara, Meyer, Heiko, Paululat, Achim

“…In , formation of the cardiac extracellular matrix (ECM) starts during embryogenesis. Assembly and incorporation of structural proteins such as Collagen IV,…”
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Identification and In Vivo Characterisation of Cardioactive Peptides in Drosophila melanogaster by Schiemann, Ronja, Lammers, Kay, Janz, Maren, Lohmann, Jana, Paululat, Achim, Meyer, Heiko

“…Neuropeptides and peptide hormones serve as critical regulators of numerous biological processes, including development, growth, reproduction, physiology, and…”
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Debris buster is a Drosophila scavenger receptor essential for airway physiology by Wingen, Almut, Carrera, Pilar, Ekaterini Psathaki, Olympia, Voelzmann, André, Paululat, Achim, Hoch, Michael

“…Scavenger receptors class B (SR-B) are multifunctional transmembrane proteins, which in vertebrates participate in lipid transport, pathogen clearance,…”
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Drosophila neprilysins control insulin signaling and food intake via cleavage of regulatory peptides by Hallier, Benjamin, Schiemann, Ronja, Cordes, Eva, Vitos-Faleato, Jessica, Walter, Stefan, Heinisch, Jürgen J, Malmendal, Anders, Paululat, Achim, Meyer, Heiko

“…Insulin and IGF signaling are critical to numerous developmental and physiological processes, with perturbations being pathognomonic of various diseases,…”
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Generation of a TMEM43 knockout human induced pluripotent stem cell line (HDZi003-A-1) using CRISPR/Cas9 by Ratnavadivel, Sandra, Dammeier, Joline, Gaertner, Anna, de Toledo, Marcelo A. Szymanski, Zenke, Martin, Gummert, Jan, Bloch Rasmussen, Torsten, Klinke, Nora, Jürgens, Kai, Meyer, Heiko, Paululat, Achim, Milting, Hendrik

“…TMEM43 (LUMA) is a ubiquitously expressed protein with unknown function. The protein is phylogenetically highly conserved and also found in Drosophila…”
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The Drosophila wing hearts originate from pericardial cells and are essential for wing maturation by Tögel, Markus, Pass, Günther, Paululat, Achim

“…In addition to the heart proper, insects possess wing hearts in the thorax to ensure regular hemolymph flow through the narrow wings. In Drosophila, the wing…”
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Combined transcriptome and proteome profiling reveal cell-type-specific functions of Drosophila garland and pericardial nephrocytes by Meyer, Heiko, Bossen, Judith, Janz, Maren, Müller, Xenia, Künzel, Sven, Roeder, Thomas, Paululat, Achim

“…Drosophila nephrocytes are specialised cells that share critical functional, morphological, and molecular features with mammalian podocytes. Accordingly,…”
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Muscle Function Assessment Using a Drosophila Larvae Crawling Assay by Post, Yanina, Paululat, Achim

“…Here we describe a simple method to measure larval muscle contraction and locomotion behavior. The method enables the user to acquire data, without the…”
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The bHLH Transcription Factor Hand Regulates the Expression of Genes Critical to Heart and Muscle Function in Drosophila melanogaster by Hallier, Benjamin, Hoffmann, Julia, Roeder, Thomas, Tögel, Markus, Meyer, Heiko, Paululat, Achim

“…Hand proteins belong to the highly conserved family of basic Helix-Loop-Helix transcription factors and are critical to distinct developmental processes,…”
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New yeast/E. coli/Drosophila triple shuttle vectors for efficient generation of Drosophila P element transformation constructs by Paululat, Achim, Heinisch, Jürgen J.

“…We have generated a set of novel triple shuttle vectors that facilitate the construction of Drosophila-P-element transformations vectors. These YED-vectors…”
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