Search Results - "Paulsson, K"

The genomic landscape of high hyperdiploid childhood acute lymphoblastic leukemia by Paulsson, Kajsa, Lilljebjörn, Henrik, Biloglav, Andrea, Olsson, Linda, Rissler, Marianne, Castor, Anders, Barbany, Gisela, Fogelstrand, Linda, Nordgren, Ann, Sjögren, Helene, Fioretos, Thoas, Johansson, Bertil

“…Kajsa Paulsson and colleagues performed whole-genome and/or whole-exome sequencing of 51 cases of high hyperdiploid pediatric acute lymphoblastic leukemia,…”
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Genomic heterogeneity in acute leukemia by Paulsson, K

“…Acquired genetic aberrations are the underlying cause of leukemogenesis in acute myeloid leukemia (AML) and acute lymphoblastic leukemia (ALL). The karyotypes…”
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Deletions of IKZF1 and SPRED1 are associated with poor prognosis in a population-based series of pediatric B-cell precursor acute lymphoblastic leukemia diagnosed between 1992 and 2011 by Olsson, L, Castor, A, Behrendtz, M, Biloglav, A, Forestier, E, Paulsson, K, Johansson, B

“…Despite the favorable prognosis of childhood acute lymphoblastic leukemia (ALL), a substantial subset of patients relapses. As this occurs not only in the high…”
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The clinical impact of IKZF1 deletions in paediatric B‐cell precursor acute lymphoblastic leukaemia is independent of minimal residual disease stratification in Nordic Society for Paediatric Haematology and Oncology treatment protocols used between 1992 and 2013 by Olsson, Linda, Ivanov Öfverholm, Ingegerd, Norén‐Nyström, Ulrika, Zachariadis, Vasilios, Nordlund, Jessica, Sjögren, Helene, Golovleva, Irina, Nordgren, Ann, Paulsson, Kajsa, Heyman, Mats, Barbany, Gisela, Johansson, Bertil

“…Summary Paediatric B‐cell precursor acute lymphoblastic leukaemias (BCP ALL) with IKZF1 deletions (∆IKZF1) are associated with a poor outcome. However, there…”
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Loss of chromosomes is the primary event in near-haploid and low-hypodiploid acute lymphoblastic leukemia by Safavi, S, Forestier, E, Golovleva, I, Barbany, G, Nord, K H, Moorman, A V, Harrison, C J, Johansson, B, Paulsson, K

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High modal number and triple trisomies are highly correlated favorable factors in childhood B-cell precursor high hyperdiploid acute lymphoblastic leukemia treated according to the NOPHO ALL 1992/2000 protocols by Paulsson, Kajsa, Forestier, Erik, Andersen, Mette K, Autio, Kirsi, Barbany, Gisela, Borgström, Georg, Cavelier, Lucia, Golovleva, Irina, Heim, Sverre, Heinonen, Kristiina, Hovland, Randi, Johannsson, Johann H, Kjeldsen, Eigil, Nordgren, Ann, Palmqvist, Lars, Johansson, Bertil

“…Between 1992 and 2008, 713 high hyperdiploid acute lymphoblastic leukemias in children aged 1-15 years were diagnosed and treated according to the Nordic…”
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Evolutionary and functional perspectives of the major histocompatibility complex class I antigen-processing machinery by Paulsson, K M

“…Major histocompatibility complex (MHC) class I molecules present antigenic peptides to CD8+ T cells, providing the basis for immune recognition of…”
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Relapsed childhood high hyperdiploid acute lymphoblastic leukemia: presence of preleukemic ancestral clones and the secondary nature of microdeletions and RTK-RAS mutations by Davidsson, J, Paulsson, K, Lindgren, D, Lilljebjörn, H, Chaplin, T, Forestier, E, Andersen, M K, Nordgren, A, Rosenquist, R, Fioretos, T, Young, B D, Johansson, B

“…Although childhood high hyperdiploid acute lymphoblastic leukemia is associated with a favorable outcome, 20% of patients still relapse. It is important to…”
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Partial 17q gain resulting from isochromosomes, unbalanced translocations and complex rearrangements is associated with gene overexpression, older age and shorter overall survival in high hyperdiploid childhood acute lymphoblastic leukemia by Herou, E, Biloglav, A, Johansson, B, Paulsson, K

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Sleep problems and the need for parental night-time attention in children with physical disabilities by Hemmingsson, H., Stenhammar, A. M., Paulsson, K.

“…Background  The aim of the study was to investigate the frequency and predictors of sleep problems and the need for parental night‐time attention in children…”
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Genomic predictors of patterns of progression in glioblastoma and possible influences on radiation field design by Holmes, Jordan A., Paulsson, Anna K., Page, Brandi R., Miller, Lance D., Liu, Wennuan, Xu, Jianfeng, Hinson, William H., Lesser, Glenn J., Laxton, Adrian W., Tatter, Stephen B., Debinski, Waldemar, Chan, Michael D.

“…We present a retrospective investigation of the role of genomics in the prediction of central versus marginal disease progression patterns for glioblastoma…”
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SNP array analysis of leukemic relapse samples after allogeneic hematopoietic stem cell transplantation with a sibling donor identifies meiotic recombination spots and reveals possible correlation with the breakpoints of acquired genetic aberrations by Paulsson, K, Lindgren, D, Johansson, B

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Distinct patterns of gained chromosomes in high hyperdiploid acute lymphoblastic leukemia with t(1;19)(q23;p13), t(9;22)(q34;q22) or MLL rearrangements by Paulsson, K, Harrison, C J, Andersen, M K, Chilton, L, Nordgren, A, Moorman, A V, Johansson, B

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Trisomy 8 as the sole chromosomal aberration in acute myeloid leukemia and myelodysplastic syndromes by Paulsson, K., Johansson, B.

“…Trisomy 8 as the sole abnormality is the most common karyotypic finding in acute myeloid leukemia (AML) and myelodysplastic syndromes (MDS), occurring in…”
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Evidence for a single-step mechanism in the origin of hyperdiploid childhood acute lymphoblastic leukemia by Paulsson, Kajsa, Mörse, Helena, Fioretos, Thoas, Behrendtz, Mikael, Strömbeck, Bodil, Johansson, Bertil

“…High hyperdiploidy (>50 chromosomes) in childhood acute lymphoblastic leukemia (ALL) is characterized by nonrandom multiple trisomies and tetrasomies involving…”
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Identification of cryptic aberrations and characterization of translocation breakpoints using array CGH in high hyperdiploid childhood acute lymphoblastic leukemia by PAULSSON, K, HEIDENBLAD, M, MORSE, H, BORG, A, FIORETOS, T, JOHANSSON, B

“…High hyperdiploidy, characterized by non-random trisomies, is the largest cytogenetic subgroup in childhood acute lymphoblastic leukemia (ALL). It is not known…”
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Radiotherapy Utilization for Patients Over Age 60 With Early Stage Breast Cancer by Paulsson, Anna K., Fowble, Barbara, Lazar, Ann A., Park, Catherine, Sherertz, Tracy

“…Recent studies have questioned the relative benefit of radiotherapy (RT) for older patients with favorable breast cancer given the lack of survival benefit and…”
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Experimental exposure of male volunteers to N-methyl-2-pyrrolidone (NMP): acute effects and pharmacokinetics of NMP in plasma and urine by Akesson, B, Paulsson, K

“…OBJECTIVES: To study the acute effects of exposure to the increasingly used solvent, N-methyl-2-pyrrolidone (NMP) in male volunteers. Further, to determine the…”
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Limited Margins Using Modern Radiotherapy Techniques Does Not Increase Marginal Failure Rate of Glioblastoma by PAULSSON, Anna K, McMULLEN, Kevin P, SHAW, Edward G, CHAN, Michael D, PEIFFER, Ann M, HINSON, William H, KEARNS, William T, JOHNSON, Annette J, LESSER, Glenn J, ELLIS, Thomas L, TATTER, Stephen B, DEBINSKI, Waldemar

“…We investigate the patterns of failure in the treatment of glioblastoma (GBM) based on clinical target volume (CTV) margin size, dose delivered to the site of…”
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Glioblastoma radiomics: can genomic and molecular characteristics correlate with imaging response patterns? by Soike, Michael H., McTyre, Emory R., Shah, Nameeta, Puchalski, Ralph B., Holmes, Jordan A., Paulsson, Anna K., Miller, Lance D., Cramer, Christina K., Lesser, Glenn J., Strowd, Roy E., Hinson, William H., Mott, Ryan T., Johnson, Annette J., Lo, Hui-Wen, Laxton, Adrian W., Tatter, Stephen B., Debinski, Waldemar, Chan, Michael D.

“…Purpose For glioblastoma (GBM), imaging response (IR) or pseudoprogression (PSP) is frequently observed after chemoradiation and may connote a favorable…”
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