Search Results - "Paulssen, Ruth H"

DNA methylation fine-tunes pro-and anti-inflammatory signalling pathways in inactive ulcerative colitis tissue biopsies by Meng, Wei, Fenton, Christopher G., Johnsen, Kay-Martin, Taman, Hagar, Florholmen, Jon, Paulssen, Ruth H.

“…DNA methylation has been implied to play a role in the immune dysfunction associated with inflammatory bowel disease (IBD) and the disease development of…”
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Methylation-Regulated Long Non-Coding RNA Expression in Ulcerative Colitis by Fenton, Christopher G, Ray, Mithlesh Kumar, Meng, Wei, Paulssen, Ruth H

“…Long non-coding RNAs (lncRNAs) have been shown to play a role in the pathogenesis of ulcerative colitis (UC). Although epigenetic processes such as DNA…”
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DNA hypo-methylation facilitates anti-inflammatory responses in severe ulcerative colitis by Taman, Hagar, Fenton, Christopher G, Anderssen, Endre, Florholmen, Jon, Paulssen, Ruth H

“…Severe ulcerative colitis (UC) is a potentially life-threatening disease with a potential colorectal cancer (CRC) risk. The aim of this study was to explore…”
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Challenges in Defining a Reference Set of Differentially Expressed lncRNAs in Ulcerative Colitis by Meta-Analysis by Fenton, Christopher G, Ray, Mithlesh Kumar, Paulssen, Ruth H

“…The study aimed to identify common differentially expressed lncRNAs from manually curated ulcerative colitis (UC) gene expression omnibus (GEO) datasets. Nine…”
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Endogenous IL-1 receptor antagonist restricts healthy and malignant myeloproliferation by Villatoro, Alicia, Cuminetti, Vincent, Bernal, Aurora, Torroja, Carlos, Cossío, Itziar, Benguría, Alberto, Ferré, Marc, Konieczny, Joanna, Vázquez, Enrique, Rubio, Andrea, Utnes, Peter, Tello, Almudena, You, Xiaona, Fenton, Christopher G., Paulssen, Ruth H., Zhang, Jing, Sánchez-Cabo, Fátima, Dopazo, Ana, Vik, Anders, Anderssen, Endre, Hidalgo, Andrés, Arranz, Lorena

“…Here we explored the role of interleukin-1β (IL-1β) repressor cytokine, IL-1 receptor antagonist (IL-1rn), in both healthy and abnormal hematopoiesis. Low…”
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Transcriptomic Landscape of Treatment-Naïve Ulcerative Colitis by Taman, Hagar, Fenton, Christopher G, Hensel, Inga V, Anderssen, Endre, Florholmen, Jon, Paulssen, Ruth H

“…Ulcerative colitis [UC] is a chronic inflammatory disease that effects the gastrointestinal tract and is considered one of the most prominent and common forms…”
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Author Correction: Endogenous IL-1 receptor antagonist restricts healthy and malignant myeloproliferation by Villatoro, Alicia, Cuminetti, Vincent, Bernal, Aurora, Torroja, Carlos, Cossío, Itziar, Benguría, Alberto, Ferré, Marc, Konieczny, Joanna, Vázquez, Enrique, Rubio, Andrea, Utnes, Peter, Tello, Almudena, You, Xiaona, Fenton, Christopher G., Paulssen, Ruth H., Zhang, Jing, Sánchez-Cabo, Fátima, Dopazo, Ana, Vik, Anders, Anderssen, Endre, Hidalgo, Andrés, Arranz, Lorena

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Novel long non-coding RNAs of relevance for ulcerative colitis pathogenesis by Ray, Mithlesh Kumar, Fenton, Christopher G., Paulssen, Ruth H.

“…The study aimed to identify yet unknown and uncharacterized long non-coding RNAs (lncRNAs) in treatment-naïve ulcerative colitis (UC), and to define their…”
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Profiling the T Cell Receptor Alpha/Delta Locus in Salmonids by Edholm, Eva-Stina, Fenton, Christopher Graham, Mondot, Stanislas, Paulssen, Ruth H, Lefranc, Marie-Paule, Boudinot, Pierre, Magadan, Susana

“…In jawed vertebrates, two major T cell populations have been characterized. They are defined as α/β or γ/δ T cells, based on the expressed T cell receptor…”
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Associations of breast cancer related exposures and gene expression profiles in normal breast tissue—The Norwegian Women and Cancer normal breast tissue study by Krum‐Hansen, Sanda, Standahl Olsen, Karina, Anderssen, Endre, Frantzen, Jan Ole, Lund, Eiliv, Paulssen, Ruth H.

“…Background Normal breast tissue is utilized in tissue‐based studies of breast carcinogenesis. While gene expression in breast tumor tissue is well explored,…”
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Deciphering normal blood gene expression variation--The NOWAC postgenome study by Dumeaux, Vanessa, Olsen, Karina S, Nuel, Gregory, Paulssen, Ruth H, Børresen-Dale, Anne-Lise, Lund, Eiliv

“…There is growing evidence that gene expression profiling of peripheral blood cells is a valuable tool for assessing gene signatures related to exposure,…”
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Cancer-associated fibroblasts from human NSCLC survive ablative doses of radiation but their invasive capacity is reduced by Hellevik, Turid, Pettersen, Ingvild, Berg, Vivian, Winberg, Jan Olof, Moe, Bjørn T, Bartnes, Kristian, Paulssen, Ruth H, Busund, Lill-Tove, Bremnes, Roy, Chalmers, Anthony, Martinez-Zubiaurre, Iñigo

“…Cancer-Associated Fibroblasts (CAFs) are significant components of solid malignancies and play central roles in cancer sustainability, invasion and metastasis…”
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Plasma fatty acid ratios affect blood gene expression profiles--a cross-sectional study of the Norwegian Women and Cancer Post-Genome Cohort by Olsen, Karina Standahl, Fenton, Christopher, Frøyland, Livar, Waaseth, Marit, Paulssen, Ruth H, Lund, Eiliv

“…High blood concentrations of n-6 fatty acids (FAs) relative to n-3 FAs may lead to a "physiological switch" towards permanent low-grade inflammation,…”
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New specific molecular targets for radio-chemotherapy of rectal cancer by Snipstad, Kristin, Fenton, Christopher G., Kjæve, Jørn, Cui, Guanglin, Anderssen, Endre, Paulssen, Ruth H.

“…Patients with locally advanced rectal cancer often receive preoperative radio-chemotherapy (RCT). The mechanisms of tumour response to radiotherapy are not…”
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The impact of partial hepatectomy on oxidative state in the liver remnant - An in vivo swine model by Florholmen-Kjær, Åse, Goll, Rasmus, Fuskevåg, Ole-Martin, Nygård, Ingvild Engdal, Paulssen, Ruth H, Revhaug, Arthur, Mortensen, Kim Erlend

“…Previous studies on oxidative state after partial hepatectomy (PHx) report conflicting data on levels of glutathione (GSH) and are mainly presented in rodent…”
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Transcriptional Signatures That Define Ulcerative Colitis in Remission by Fenton, Christopher G, Taman, Hagar, Florholmen, Jon, Sørbye, Sveinung W, Paulssen, Ruth H

“…Abstract Background This study addresses whether existing specific transcriptional profiles can improve and support the current status of the definition of…”
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Identifying predictive signalling networks for Vedolizumab response in ulcerative colitis by Singh, Amrinder, Fenton, Christopher G., Anderssen, Endre, Paulssen, Ruth H.

“…Background In ulcerative colitis (UC), the molecular mechanisms that drive disease development and patient response to therapy are not well understood. A…”
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Anti-apoptotic genes and non-coding RNAs are potential outcome predictors for ulcerative colitis by Meng, Wei, Johnsen, Kay-Martin, Fenton, Christopher G., Florholmen, Jon, Paulssen, Ruth H.

“…Due to the lack of clinical, immunologic, genetic, and laboratory markers to predict remission in ulcerative colitis (UC) without relapse, there is no clear…”
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Genome-wide DNA Methylation in Treatment-naïve Ulcerative Colitis by Taman, Hagar, Fenton, Christopher G, Hensel, Inga V, Anderssen, Endre, Florholmen, Jon, Paulssen, Ruth H

“…The aim of this study was to investigate the genome-wide DNA methylation status in treatment-naïve ulcerative colitis [UC], and to explore the relationship…”
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Identifying anti-TNF response biomarkers in ulcerative colitis using a diffusion-based signalling model by Singh, Amrinder, Anderssen, Endre, Fenton, Christopher G, Paulssen, Ruth H

“…Resistance to anti-TNF therapy in subgroups of ulcerative colitis (UC) patients is a major challenge and incurs significant treatment costs. Identification of…”
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