Search Results - "Paulsen, Sarah"

GFRAL is the receptor for GDF15 and is required for the anti-obesity effects of the ligand by Yang, Linda, Chang, Chih-Chuan, Sun, Zhe, Madsen, Dennis, Zhu, Haisun, Padkjær, Søren B, Wu, Xiaoai, Huang, Tao, Hultman, Karin, Paulsen, Sarah J, Wang, Jishu, Bugge, Anne, Frantzen, Jane Boesen, Nørgaard, Per, Jeppesen, Jacob Fuglsbjerg, Yang, Zhiru, Secher, Anna, Chen, Haibin, Li, Xun, John, Linu Mary, Shan, Bing, He, Zhenhua, Gao, Xiang, Su, Jing, Hansen, Kristian T, Yang, Wei, Jørgensen, Sebastian Beck

“…GDF15 has potent anti-obesity effects, but its receptor was unknown. GFRAL has now been identified as the receptor that mediates GDF15's effects via central…”
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Semaglutide lowers body weight in rodents via distributed neural pathways by Gabery, Sanaz, Salinas, Casper G, Paulsen, Sarah J, Ahnfelt-Rønne, Jonas, Alanentalo, Tomas, Baquero, Arian F, Buckley, Stephen T, Farkas, Erzsébet, Fekete, Csaba, Frederiksen, Klaus S, Helms, Hans Christian C, Jeppesen, Jacob F, John, Linu M, Pyke, Charles, Nøhr, Jane, Lu, Tess T, Polex-Wolf, Joseph, Prevot, Vincent, Raun, Kirsten, Simonsen, Lotte, Sun, Gao, Szilvásy-Szabó, Anett, Willenbrock, Hanni, Secher, Anna, Knudsen, Lotte Bjerre, Hogendorf, Wouter Frederik Johan

“…Semaglutide, a glucagon-like peptide 1 (GLP-1) analog, induces weight loss, lowers glucose levels, and reduces cardiovascular risk in patients with diabetes…”
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Expression of the fatty acid receptor GPR120 in the gut of diet-induced-obese rats and its role in GLP-1 secretion by Paulsen, Sarah Juel, Larsen, Leif Kongskov, Hansen, Gitte, Chelur, Shekar, Larsen, Philip Just, Vrang, Niels

“…Stimulation of the G protein coupled receptor GPR120 has been shown to have anti-inflammatory and insulin-sensitizing effects, to promote glucagon like…”
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Effect of Roux-en-Y gastric bypass on the distribution and hormone expression of small-intestinal enteroendocrine cells in obese patients with type 2 diabetes by Rhee, Nicolai A., Wahlgren, Camilla D., Pedersen, Jens, Mortensen, Brynjulf, Langholz, Ebbe, Wandall, Erik P., Friis, Steffen U., Vilmann, Peter, Paulsen, Sarah J., Kristiansen, Viggo B., Jelsing, Jacob, Dalbøge, Louise S., Poulsen, Steen S., Holst, Jens J., Vilsbøll, Tina, Knop, Filip K.

“…Aims/hypothesis We studied the impact of Roux-en-Y gastric bypass (RYGB) on the density and hormonal gene expression of small-intestinal enteroendocrine cells…”
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A genetic map of the mouse dorsal vagal complex and its role in obesity by Ludwig, Mette Q., Cheng, Wenwen, Gordian, Desiree, Lee, Julie, Paulsen, Sarah J., Hansen, Stine N., Egerod, Kristoffer L., Barkholt, Pernille, Rhodes, Christopher J., Secher, Anna, Knudsen, Lotte Bjerre, Pyke, Charles, Myers, Martin G., Pers, Tune H.

“…The brainstem dorsal vagal complex (DVC) is known to regulate energy balance and is the target of appetite-suppressing hormones, such as glucagon-like peptide…”
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Long-term characterization of the diet-induced obese and diet-resistant rat model: a polygenetic rat model mimicking the human obesity syndrome by Madsen, Andreas Nygaard, Hansen, Gitte, Paulsen, Sarah Juel, Lykkegaard, Kirsten, Tang-Christensen, Mads, Hansen, Harald S, Levin, Barry E, Larsen, Philip Just, Knudsen, Lotte Bjerre, Fosgerau, Keld, Vrang, Niels

“…The availability of useful animal models reflecting the human obesity syndrome is crucial in the search for novel compounds for the pharmacological treatment…”
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The DPP-IV inhibitor linagliptin and GLP-1 induce synergistic effects on body weight loss and appetite suppression in the diet-induced obese rat by Hansen, Henrik H., Hansen, Gitte, Paulsen, Sarah, Vrang, Niels, Mark, Michael, Jelsing, Jacob, Klein, Thomas

“…Linagliptin is a dipeptidyl peptidase (DPP)-IV inhibitor approved for the treatment of type 2 diabetes. DPP-IV inhibitors are considered weight neutral,…”
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Expression and Distribution of Glucagon-Like Peptide-1 Receptor mRNA, Protein and Binding in the Male Nonhuman Primate (Macaca mulatta) Brain by Heppner, Kristy M, Kirigiti, Melissa, Secher, Anna, Paulsen, Sarah Juel, Buckingham, Rikley, Pyke, Charles, Knudsen, Lotte B, Vrang, Niels, Grove, Kevin L

“…Glucagon-like peptide-1 (GLP-1) is released from endocrine L-cells lining the gut in response to food ingestion. However, GLP-1 is also produced in the nucleus…”
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Investigation of the direct effects of salmon calcitonin on human osteoarthritic chondrocytes by Sondergaard, Bodil-Cecilie, Madsen, Suzi H, Segovia-Silvestre, Toni, Paulsen, Sarah J, Christiansen, Thorbjorn, Pedersen, Christian, Bay-Jensen, Anne-Christine, Karsdal, Morten A

“…Calcitonin has been demonstrated to have chondroprotective effects under pre-clinical settings. It is debated whether this effect is mediated through…”
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Epstein-Barr Virus-Encoded BILF1 Is a Constitutively Active G Protein-Coupled Receptor by Paulsen, Sarah J, Rosenkilde, Mette M, Eugen-Olsen, Jesper, Kledal, Thomas N

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Faecal sample storage without ethanol for up to 24 h followed by freezing performs better than storage with ethanol for shotgun metagenomic microbiome analysis in patients with inflammatory and non-inflammatory intestinal diseases and healthy controls by Grønbæk, Ida Marie Bruun, Mollerup, Sarah, Halkjær, Sofie Ingdam, Paulsen, Sarah Juel, Pinholt, Mette, Westh, Henrik, Petersen, Andreas Munk

“…Abstract Objective The influence of different faecal collection methods on metagenomic analyses remains under discussion, and there is no general agreement on…”
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Hypertrophy dependent doubling of L-cells in Roux-en-Y gastric bypass operated rats by Hansen, Carl Frederik, Bueter, Marco, Theis, Nadine, Lutz, Thomas, Paulsen, Sarah, Dalbøge, Louise S, Vrang, Niels, Jelsing, Jacob

“…Roux-en-Y gastric bypass (RYGB) leads to a rapid remission of type 2 diabetes mellitus (T2DM), but the underlying mode of action remains incompletely…”
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Characterization of β-Cell Mass and Insulin Resistance in Diet-induced Obese and Diet-resistant Rats by Paulsen, Sarah J, Jelsing, Jacob, Madsen, Andreas N, Hansen, Gitte, Lykkegaard, Kirsten, Larsen, Leif K, Larsen, Philip J, Levin, Barry E, Vrang, Niels

“…The selectively bred diet-induced obese (DIO) and diet-resistant (DR) rats represent a polygenetic animal model mimicking most clinical variables…”
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It Takes Two Generations to Forget by PAULSEN, SARAH

“…Sarah Paulsen, It Takes Two Generations to Forget, 2017. Collage and colored pencil on paper, 15 × 22 in. This piece is part of Paulsen's series “White…”
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The microbiome of the appendix differs in patients with and without appendicitis: A prospective cohort study by Fonnes, Siv, Mollerup, Sarah, Paulsen, Sarah Juel, Holzknecht, Barbara Juliane, Westh, Henrik, Rosenberg, Jacob

“…Appendicitis seems to be a disease of infectious origin, but the detailed pathogenesis is unknown. We aimed to investigate the microbiome of the appendix lumen…”
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Laser capture microdissection and quantitative-PCR analysis by Paulsen, Sarah J, Larsen, Leif K

“…Laser capture microdissection (LCM) provides an efficient and precise method for the sampling of single cells or subgroups of cells in heterogeneous tissues…”
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Molecular epidemiology of the SARS-CoV-2 variant Omicron BA.2 sub-lineage in Denmark, 29 November 2021 to 2 January 2022 by Fonager, Jannik, Bennedbæk, Marc, Bager, Peter, Wohlfahrt, Jan, Ellegaard, Kirsten Maren, Ingham, Anna Cäcilia, Edslev, Sofie Marie, Stegger, Marc, Sieber, Raphael Niklaus, Lassauniere, Ria, Fomsgaard, Anders, Lillebaek, Troels, Svarrer, Christina Wiid, Møller, Frederik Trier, Møller, Camilla Holten, Legarth, Rebecca, Sydenham, Thomas Vognbjerg, Steinke, Kat, Paulsen, Sarah Juel, Castruita, José Alfredo Samaniego, Schneider, Uffe Vest, Schouw, Christian Højte, Nielsen, Xiaohui Chen, Overvad, Maria, Nielsen, Rikke Thoft, Marvig, Rasmus L, Pedersen, Martin Schou, Nielsen, Lene, Nilsson, Line Lynge, Bybjerg-Grauholm, Jonas, Tarpgaard, Irene Harder, Ebsen, Tine Snejbjerg, Lam, Janni Uyen Hoa, Gunalan, Vithiagaran, Rasmussen, Morten

“…Following emergence of the SARS-CoV-2 variant Omicron in November 2021, the dominant BA.1 sub-lineage was replaced by the BA.2 sub-lineage in Denmark. We…”
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High-resolution epidemiological landscape from  ~290,000 SARS-CoV-2 genomes from Denmark by Khurana, Mark P., Curran-Sebastian, Jacob, Scheidwasser, Neil, Morgenstern, Christian, Rasmussen, Morten, Fonager, Jannik, Stegger, Marc, Tang, Man-Hung Eric, Juul, Jonas L., Escobar-Herrera, Leandro Andrés, Møller, Frederik Trier, Albertsen, Mads, Kraemer, Moritz U. G., du Plessis, Louis, Jokelainen, Pikka, Lehmann, Sune, Krause, Tyra G., Ullum, Henrik, Duchêne, David A., Mortensen, Laust H., Bhatt, Samir

“…Vast amounts of pathogen genomic, demographic and spatial data are transforming our understanding of SARS-CoV-2 emergence and spread. We examined the drivers…”
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Stereological assessment of pancreatic beta‐cell mass development in male Zucker Diabetic Fatty (ZDF) rats: correlation with pancreatic beta‐cell function by Paulsen, Sarah Juel, Vrang, Niels, Larsen, Leif Kongskov, Larsen, Philip Just, Jelsing, Jacob

“…The present study was initiated to improve our understanding of pancreatic beta‐cell dynamics in male Zucker Diabetic Fatty (ZDF) rats and hence provide a…”
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Black Power and Neighborhood Organizing in Minneapolis, Minnesota: The Way Community Center, 1966-1971 by Paulsen, Sarah Jayne

“…The Way Opportunities Unlimited, Inc. was a non-profit community center that operated from 1966–1984 in Minneapolis, Minnesota. Inspired by the national black…”
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