Search Results - "Paulsen, Marianne H"

Metallo-β-lactamase inhibitors by bioisosteric replacement: Preparation, activity and binding by Skagseth, Susann, Akhter, Sundus, Paulsen, Marianne H., Muhammad, Zeeshan, Lauksund, Silje, Samuelsen, Ørjan, Leiros, Hanna-Kirsti S., Bayer, Annette

“…Bacterial resistance is compromising the use of β-lactam antibiotics including carbapenems. The main resistance mechanism against β-lactams is hydrolysis of…”
Get full text

Amphipathic Barbiturates as Mimics of Antimicrobial Peptides and the Marine Natural Products Eusynstyelamides with Activity against Multi-resistant Clinical Isolates by Paulsen, Marianne H, Engqvist, Magnus, Ausbacher, Dominik, Anderssen, Trude, Langer, Manuel K, Haug, Tor, Morello, Glenn R, Liikanen, Laura E, Blencke, Hans-Matti, Isaksson, Johan, Juskewitz, Eric, Bayer, Annette, Strøm, Morten B

“…We report a series of synthetic cationic amphipathic barbiturates inspired by the pharmacophore model of small antimicrobial peptides (AMPs) and the marine…”
Get full text

Antimicrobial activity of amphipathic α,α-disubstituted β-amino amide derivatives against ESBL – CARBA producing multi-resistant bacteria; effect of halogenation, lipophilicity and cationic character by Paulsen, Marianne H., Ausbacher, Dominik, Bayer, Annette, Engqvist, Magnus, Hansen, Terkel, Haug, Tor, Anderssen, Trude, Andersen, Jeanette H., Sollid, Johanna U. Ericson, Strøm, Morten B.

“…The rapid emergence and spread of multi-resistant bacteria have created an urgent need for new antimicrobial agents. We report here a series of amphipathic…”
Get full text

Tailored anti-biofilm activity - Liposomal delivery for mimic of small antimicrobial peptide by Hemmingsen, Lisa Myrseth, Giordani, Barbara, Paulsen, Marianne H, Vanić, Željka, Flaten, Gøril Eide, Vitali, Beatrice, Basnet, Purusotam, Bayer, Annette, Strøm, Morten B, Škalko-Basnet, Nataša

“…The eradication of bacteria embedded in biofilms is among the most challenging obstacles in the management of chronic wounds. These biofilms are found in most…”
Get more information

An amphipathic cyclic tetrapeptide scaffold containing halogenated β2,2‐amino acids with activity against multiresistant bacteria by Paulsen, Marianne H., Karlsen, Eskil André, Ausbacher, Dominik, Anderssen, Trude, Bayer, Annette, Ochtrop, Philipp, Hedberg, Christian, Haug, Tor, Ericson Sollid, Johanna U., Strøm, Morten B.

“…The present study describes the synthesis and biological studies of a small series of head‐to‐tail cyclic tetrapeptides of the general structure…”
Get full text

An amphipathic cyclic tetrapeptide scaffold containing halogenated β 2,2 -amino acids with activity against multiresistant bacteria by Paulsen, Marianne H, Karlsen, Eskil André, Ausbacher, Dominik, Anderssen, Trude, Bayer, Annette, Ochtrop, Philipp, Hedberg, Christian, Haug, Tor, Ericson Sollid, Johanna U, Strøm, Morten B

“…The present study describes the synthesis and biological studies of a small series of head-to-tail cyclic tetrapeptides of the general structure c(Lys-β…”
Get full text