Search Results - "Paull, Daniel"

Catalytic, asymmetric reactions of ketenes and ketene enolates by Paull, Daniel H., Weatherwax, Anthony, Lectka, Thomas

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Bifunctional Catalyst Promotes Highly Enantioselective Bromolactonizations To Generate Stereogenic C–Br Bonds by Paull, Daniel H, Fang, Chao, Donald, James R, Pansick, Andrew D, Martin, Stephen F

“…A novel bifunctional catalyst derived from BINOL has been developed that promotes the highly enantioselective bromolactonizations of a number of structurally…”
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Resveratrol analogues surprisingly effective against triple‑negative breast cancer, independent of ERα by Horgan, Xylia J, Tatum, Hannah, Brannan, Emily, Paull, Daniel H, Rhodes, Lyndsay V

“…Resveratrol, a plant‑derived stilbene compound, has exhibited anticancerous properties, including breast cancer. Stilbenes have a molecular structure highly…”
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Bifunctional Asymmetric Catalysis: Cooperative Lewis Acid/Base Systems by Paull, Daniel H, Abraham, Ciby J, Scerba, Michael T, Alden-Danforth, Ethan, Lectka, Thomas

“…In the field of catalytic, asymmetric synthesis, there is a growing emphasis on multifunctional systems, in which multiple parts of a catalyst or multiple…”
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Genetic Drift Can Compromise Mitochondrial Replacement by Nuclear Transfer in Human Oocytes by Yamada, Mitsutoshi, Emmanuele, Valentina, Sanchez-Quintero, Maria J., Sun, Bruce, Lallos, Gregory, Paull, Daniel, Zimmer, Matthew, Pagett, Shardonay, Prosser, Robert W., Sauer, Mark V., Hirano, Michio, Egli, Dieter

“…Replacement of mitochondria through nuclear transfer between oocytes of two different women has emerged recently as a strategy for preventing inheritance of…”
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Co-Occurrence of Triclocarban and Triclosan in U.S. Water Resources by Halden, Rolf U, Paull, Daniel H

“…Triclocarban (TCC) and triclosan (TCS) are antimicrobial additives in personal care products. Whereas TCS has been studied extensively, the environmental fate…”
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Lipid Deprivation Induces a Stable, Naive-to-Primed Intermediate State of Pluripotency in Human PSCs by Cornacchia, Daniela, Zhang, Chao, Zimmer, Bastian, Chung, Sun Young, Fan, Yujie, Soliman, Mohamed A., Tchieu, Jason, Chambers, Stuart M., Shah, Hardik, Paull, Daniel, Konrad, Csaba, Vincendeau, Michelle, Noggle, Scott A., Manfredi, Giovanni, Finley, Lydia W.S., Cross, Justin R., Betel, Doron, Studer, Lorenz

“…Current challenges in capturing naive human pluripotent stem cells (hPSCs) suggest that the factors regulating human naive versus primed pluripotency remain…”
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From Bifunctional to Trifunctional (Tricomponent Nucleophile–Transition Metal–Lewis Acid) Catalysis: The Catalytic, Enantioselective α-Fluorination of Acid Chlorides by Erb, Jeremy, Paull, Daniel H, Dudding, Travis, Belding, Lee, Lectka, Thomas

“…We report in full detail our studies on the catalytic, asymmetric α-fluorination of acid chlorides, a practical method that produces an array of…”
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Enantioselective Halolactonization Reactions using BINOL-Derived Bifunctional Catalysts: Methodology, Diversification, and Applications by Klosowski, Daniel W, Hethcox, J. Caleb, Paull, Daniel H, Fang, Chao, Donald, James R, Shugrue, Christopher R, Pansick, Andrew D, Martin, Stephen F

“…A general protocol is described for inducing enantioselective halolactonizations of unsaturated carboxylic acids using novel bifunctional organic catalysts…”
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Human oocytes reprogram adult somatic nuclei of a type 1 diabetic to diploid pluripotent stem cells by Yamada, Mitsutoshi, Johannesson, Bjarki, Sagi, Ido, Burnett, Lisa Cole, Kort, Daniel H., Prosser, Robert W., Paull, Daniel, Nestor, Michael W., Freeby, Matthew, Greenberg, Ellen, Goland, Robin S., Leibel, Rudolph L., Solomon, Susan L., Benvenisty, Nissim, Sauer, Mark V., Egli, Dieter

“…Here human embryonic stem cell lines are derived by somatic cell nuclear transfer from cells of a newborn and from skin cells of an adult, a female with type 1…”
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Enantioselective Iodolactonization of Disubstituted Olefinic Acids Using a Bifunctional Catalyst by Fang, Chao, Paull, Daniel H, Hethcox, J. Caleb, Shugrue, Christopher R, Martin, Stephen F

“…The enantioselective iodolactonizations of a series of diversely substituted olefinic carboxylic acids are promoted by a BINOL-derived, bifunctional catalyst…”
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Comparable Frequencies of Coding Mutations and Loss of Imprinting in Human Pluripotent Cells Derived by Nuclear Transfer and Defined Factors by Johannesson, Bjarki, Sagi, Ido, Gore, Athurva, Paull, Daniel, Yamada, Mitsutoshi, Golan-Lev, Tamar, Li, Zhe, LeDuc, Charles, Shen, Yufeng, Stern, Samantha, Xu, Nanfang, Ma, Hong, Kang, Eunju, Mitalipov, Shoukhrat, Sauer, Mark V., Zhang, Kun, Benvenisty, Nissim, Egli, Dieter

“…The recent finding that reprogrammed human pluripotent stem cells can be derived by nuclear transfer into human oocytes as well as by induced expression of…”
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Asymmetric formal total synthesis of the stemofoline alkaloids: the evolution, development, and application of a catalytic dipolar cycloaddition cascade by Shanahan, Charles S., Fang, Chao, Paull, Daniel H., Martin, Stephen F.

“…A formal synthesis of didehydrostemofoline and isodidehydrostemofoline has been accomplished by preparing an intermediate in the Overman synthesis of these…”
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Catalytic, Asymmetric α-Fluorination of Acid Chlorides: Dual Metal−Ketene Enolate Activation by Paull, Daniel H, Scerba, Michael T, Alden-Danforth, Ethan, Widger, Leland R, Lectka, Thomas

“…In this Communication, we disclose a catalytic, highly enantioselective (up to >99% ee) α-fluorination of acid chlorides to produce a variety of optically…”
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Stem cell‐derived retinal pigment epithelium from patients with age‐related macular degeneration exhibit reduced metabolism and matrix interactions by Gong, Jie, Cai, Hui, Noggle, Scott, Paull, Daniel, Rizzolo, Lawrence J., Del Priore, Lucian V., Fields, Mark A.

“…Modeling age‐related macular degeneration (AMD) is challenging, because it is a multifactorial disease. To focus on interactions between the retinal pigment…”
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Enantioselective Formal Total Syntheses of Didehydrostemofoline and Isodidehydrostemofoline through a Catalytic Dipolar Cycloaddition Cascade by Fang, Chao, Shanahan, Charles S., Paull, Daniel H., Martin, Stephen F.

“…Sweet to the core: Enantioselective formal total syntheses of the title compounds were accomplished in 24 steps from 2‐deoxy‐D‐ribose. The synthesis features a…”
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Catalytic, Enantioselective Bifunctional Inverse Electron Demand Hetero-Diels−Alder Reactions of Ketene Enolates and o-Benzoquinone Diimides by Abraham, Ciby J, Paull, Daniel H, Scerba, Michael T, Grebinski, James W, Lectka, Thomas

“…In this Communication, we report a system in which an achiral Lewis acid (activating the diene) works in concert with a chiral nucleophile (dienophile) to…”
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FocA: A deep learning tool for reliable, near-real-time imaging focus analysis in automated cell assay pipelines by Winchell, Jeff, Comolet, Gabriel, Buckley-Herd, Geoff, Hutson, Dillion, Bose, Neeloy, Paull, Daniel, Migliori, Bianca

“…The increasing use of automation in cellular assays and cell culture presents significant opportunities to enhance the scale and throughput of imaging assays,…”
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Reactive Astrocytes Derived From Human Induced Pluripotent Stem Cells Suppress Oligodendrocyte Precursor Cell Differentiation by Smith, Matthew D, Chamling, Xitiz, Gill, Alexander J, Martinez, Hector, Li, Weifeng, Fitzgerald, Kathryn C, Sotirchos, Elias S, Moroziewicz, Dorota, Bauer, Lauren, Paull, Daniel, Gharagozloo, Marjan, Bhargava, Pavan, Zack, Donald J, Fossati, Valentina, Calabresi, Peter A

“…Astrocytes are instrumental in maintaining central nervous system (CNS) homeostasis and responding to injury. A major limitation of studying neurodegenerative…”
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Analysis of Triclocarban in Aquatic Samples by Liquid Chromatography Electrospray Ionization Mass Spectrometry by Halden, Rolf U, Paull, Daniel H

“…Triclocarban, N-(4-chlorophenyl)-N‘-(3,4-dichlorophenyl)urea, is a polychlorinated phenyl urea pesticide, marketed under the trademark TCC and used primarily…”
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