Search Results - "Pauline, T"

Race-aware algorithms: Fairness, nondiscrimination and affirmative action by Kim, Pauline T

“…The growing use of predictive algorithms is increasing concerns that they may discriminate, but mitigating or removing bias requires designers to be aware of…”
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Three-Component Azidation of Styrene-Type Double Bonds: Light-Switchable Behavior of a Copper Photoredox Catalyst by Fumagalli, Gabriele, Rabet, Pauline T. G., Boyd, Scott, Greaney, Michael F.

“…[Cu(dap)2]Cl effectively catalyzes azide addition from the Zhdankin reagent to styrene‐type double bonds, and subsequent addition of a third component to the…”
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Benzylic C–H Azidation Using the Zhdankin Reagent and a Copper Photoredox Catalyst by Rabet, Pauline T. G, Fumagalli, Gabriele, Boyd, Scott, Greaney, Michael F

“…An azidation method for C–N bond formation at benzylic C–H positions is described using copper-catalyzed visible light photochemistry and the Zhdankin…”
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Adalimumab for prevention of uveitic flare in patients with inactive non-infectious uveitis controlled by corticosteroids (VISUAL II): a multicentre, double-masked, randomised, placebo-controlled phase 3 trial by Nguyen, Quan Dong, Prof Dr, Merrill, Pauline T, MD, Jaffe, Glenn J, Prof, Dick, Andrew D, Prof, Kurup, Shree Kumar, Prof, Sheppard, John, MD, Schlaen, Ariel, MD, Pavesio, Carlos, MD, Cimino, Luca, MD, Van Calster, Joachim, MD, Camez, Anne A, MD, Kwatra, Nisha V, PhD, Song, Alexandra P, MD, Kron, Martina, Prof, Tari, Samir, MD, Brézin, Antoine P, Prof

“…Summary Background Non-infectious uveitis is a potentially sight-threatening ocular disorder caused by chronic inflammation and its complications. Therapeutic…”
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MANIPULATING OPPORTUNITY by Kim, Pauline T.

“…Concerns about online manipulation have centered on fears about undermining the autonomy of consumers and citizens. What has been overlooked is the risk that…”
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HR‐pQCT Measures of Bone Microarchitecture Predict Fracture: Systematic Review and Meta‐Analysis by Mikolajewicz, Nicholas, Bishop, Nick, Burghardt, Andrew J, Folkestad, Lars, Hall, Anthony, Kozloff, Kenneth M, Lukey, Pauline T, Molloy‐Bland, Michael, Morin, Suzanne N, Offiah, Amaka C, Shapiro, Jay, Rietbergen, Bert, Wager, Kim, Willie, Bettina M, Komarova, Svetlana V, Glorieux, Francis H

“…ABSTRACT High‐resolution peripheral quantitative computed tomography (HR‐pQCT) is a noninvasive imaging modality for assessing volumetric bone mineral density…”
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Daily Home Spirometry: An Effective Tool for Detecting Progression in Idiopathic Pulmonary Fibrosis by Russell, Anne-Marie, Adamali, Huzaifa, Molyneaux, Philip L, Lukey, Pauline T, Marshall, Richard P, Renzoni, Elisabetta A, Wells, Athol U, Maher, Toby M

“…Recent clinical trial successes have created an urgent need for earlier and more sensitive endpoints of disease progression in idiopathic pulmonary fibrosis…”
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The 0.19-mg Fluocinolone Acetonide Intravitreal Implant Reduces Treatment Burden in Diabetic Macular Edema by Merrill, Pauline T., Holekamp, Nancy, Roth, Daniel, Kasper, Jonathan, Grigorian, Ruben

“…To assess treatment burden in patients with diabetic macular edema (DME) after the 0.19-mg fluocinolone acetonide (FAc) intravitreal implant (ILUVIEN)…”
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Interim Cosmetic and Toxicity Results From RAPID: A Randomized Trial of Accelerated Partial Breast Irradiation Using Three-Dimensional Conformal External Beam Radiation Therapy by OLIVOTTO, Ivo A, WHELAN, Timothy J, GERMAIN, Isabelle, AKRA, Mohamed, REED, Melanie, FYLES, Anthony, TROTTER, Theresa, PERERA, Francisco, BECKHAM, Wayne, LEVINE, Mark N, JULIAN, Jim A, PARPIA, Sameer, KIM, Do-Hoon, BERRANG, Tanya, TRUONG, Pauline T, KONG, Iwa, COCHRANE, Brandy, NICHOL, Alan, ROY, Isabelle

“…To report interim cosmetic and toxicity results of a multicenter randomized trial comparing accelerated partial-breast irradiation (APBI) using…”
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Longitudinal change in collagen degradation biomarkers in idiopathic pulmonary fibrosis: an analysis from the prospective, multicentre PROFILE study by Jenkins, R Gisli, PhD, Simpson, Juliet K, PhD, Saini, Gauri, MD, Bentley, Jane H, PhD, Russell, Anne-Marie, MSc, Braybrooke, Rebecca, RGN, Molyneaux, Philip L, MD, McKeever, Tricia M, PhD, Wells, Athol U, MD, Flynn, Aiden, PhD, Hubbard, Richard B, Prof, Leeming, Diana J, PhD, Marshall, Richard P, PhD, Karsdal, Morten A, PhD, Lukey, Pauline T, PhD, Maher, Toby M, Dr

“…Summary Background Idiopathic pulmonary fibrosis, a progressive and inevitably fatal disorder, has a highly variable clinical course. Biomarkers that reflect…”
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Arylation Using Sulfonamides: Phenylacetamide Synthesis through Tandem Acylation–Smiles Rearrangement by Barlow, Helen L, Rabet, Pauline T. G, Durie, Alastair, Evans, Tim, Greaney, Michael F

“…A range of electron-poor and heterocyclic sulfonamides react with phenylacetyl chlorides to produce benzhydryl derivatives in a single step. The reaction…”
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Corrigendum to “The 0.19-mg Fluocinolone Acetonide Intravitreal Implant Reduces Treatment Burden in Diabetic Macular Edema” [Am J Ophthalmol 2023;248;16-23] by Merrill, Pauline T., Holekamp, Nancy, Roth, Daniel, Kasper, Jonathan, Grigorian, Ruben

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Deleterious Effects of Amyloid β Oligomers Acting as an Extracellular Scaffold for mGluR5 by Renner, Marianne, Lacor, Pascale N., Velasco, Pauline T., Xu, Jian, Contractor, Anis, Klein, William L., Triller, Antoine

“…Soluble oligomers of amyloid β (Aβ) play a role in the memory impairment characteristic of Alzheimer's disease. Acting as pathogenic ligands, Aβ oligomers bind…”
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Tumor-infiltrating lymphocytes predict response to anthracycline-based chemotherapy in estrogen receptor-negative breast cancer by West, Nathan R, Milne, Katy, Truong, Pauline T, Macpherson, Nicol, Nelson, Brad H, Watson, Peter H

“…Infiltration of breast tumors by tumor-infiltrating lymphocytes (TIL) has been associated with sensitivity to anthracycline-based chemotherapy. However, it is…”
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Metal‐Free Intermolecular Aminoarylation of Alkynes by Rabet, Pauline T. G., Boyd, Scott, Greaney, Michael F.

“…A metal‐free aminoarylation of internal alkynes is described, yielding tetrasubstituted enaminoates. The transformation proceeds in good to excellent yields…”
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Exploration of a potent PI3 kinase/mTOR inhibitor as a novel anti-fibrotic agent in IPF by Mercer, Paul F, Woodcock, Hannah V, Eley, Jessica D, Platé, Manuela, Sulikowski, Michal G, Durrenberger, Pascal F, Franklin, Linda, Nanthakumar, Carmel B, Man, Yim, Genovese, Federica, McAnulty, Robin J, Yang, Shuying, Maher, Toby M, Nicholson, Andrew G, Blanchard, Andy D, Marshall, Richard P, Lukey, Pauline T, Chambers, Rachel C

“…Idiopathic pulmonary fibrosis (IPF) is the most rapidly progressive and fatal of all fibrotic conditions with no curative therapies. Common pathomechanisms…”
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Intravitreal Sirolimus for Noninfectious Uveitis: A Phase III Sirolimus Study Assessing Double-masKed Uveitis TReAtment (SAKURA) by Nguyen, Quan Dong, MD, MSc, Merrill, Pauline T., MD, Clark, W. Lloyd, MD, Banker, Alay S., MD, Fardeau, Christine, MD, Franco, Pablo, MD, LeHoang, Phuc, MD, PhD, Ohno, Shigeaki, MD, PhD, Rathinam, Sivakumar R., FAMS, PhD, Thurau, Stephan, MD, FEBO, Abraham, Abu, MD, Wilson, Laura, MD, Yang, Yang, PhD, Shams, Naveed, MD, PhD

“…Purpose To evaluate the efficacy and safety of intravitreal sirolimus in the treatment of noninfectious uveitis (NIU) of the posterior segment (i.e.,…”
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An epithelial biomarker signature for idiopathic pulmonary fibrosis: an analysis from the multicentre PROFILE cohort study by Maher, Toby M, Oballa, Eunice, Simpson, Juliet K, Porte, Joanne, Habgood, Anthony, Fahy, William A, Flynn, Aiden, Molyneaux, Philip L, Braybrooke, Rebecca, Divyateja, Hrushikesh, Parfrey, Helen, Rassl, Doris, Russell, Anne-Marie, Saini, Gauri, Renzoni, Elisabetta A, Duggan, Anne-Marie, Hubbard, Richard, Wells, Athol U, Lukey, Pauline T, Marshall, Richard P, Jenkins, R Gisli

“…Idiopathic pulmonary fibrosis (IPF) is a progressive, fatal disorder with a variable disease trajectory. The aim of this study was to assess potential…”
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Translational pharmacology of an inhaled small molecule αvβ6 integrin inhibitor for idiopathic pulmonary fibrosis by John, Alison E., Graves, Rebecca H., Pun, K. Tao, Vitulli, Giovanni, Forty, Ellen J., Mercer, Paul F., Morrell, Josie L., Barrett, John W., Rogers, Rebecca F., Hafeji, Maryam, Bibby, Lloyd I., Gower, Elaine, Morrison, Valerie S., Man, Yim, Roper, James A., Luckett, Jeni C., Borthwick, Lee A., Barksby, Ben S., Burgoyne, Rachel A., Barnes, Rory, Le, Joelle, Flint, David J., Pyne, Susan, Habgood, Anthony, Organ, Louise A., Joseph, Chitra, Edwards-Pritchard, Rochelle C., Maher, Toby M., Fisher, Andrew J., Gudmann, Natasja Stæhr, Leeming, Diana J., Chambers, Rachel C., Lukey, Pauline T., Marshall, Richard P., Macdonald, Simon J. F., Jenkins, R. Gisli, Slack, Robert J.

“…The αvβ6 integrin plays a key role in the activation of transforming growth factor-β (TGFβ), a pro-fibrotic mediator that is pivotal to the development of…”
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Protection of synapses against Alzheimer's-linked toxins: Insulin signaling prevents the pathogenic binding of Aβ oligomers by De Felice, Fernanda G, Vieira, Marcelo N.N, Bomfim, Theresa R, Decker, Helena, Velasco, Pauline T, Lambert, Mary P, Viola, Kirsten L, Zhao, Wei-Qin, Ferreira, Sergio T, Klein, William L

“…Synapse deterioration underlying severe memory loss in early Alzheimer's disease (AD) is thought to be caused by soluble amyloid beta (Aβ) oligomers…”
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