Search Results - "Paulin, L."

Sensitive ELISA Method for the Measurement of Catabolites of Antibody–Drug Conjugates (ADCs) in Target Cancer Cells by Salomon, Paulin L, Singh, Rajeeva

“…A new, sensitive ELISA method has been developed which measures catabolites in cells and media upon processing of antibody–drug conjugates (ADCs) by target…”
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More than constipation – bowel symptoms in Parkinson's disease and their connection to gut microbiota by Mertsalmi, T. H., Aho, V. T. E., Pereira, P. A. B., Paulin, L., Pekkonen, E., Auvinen, P., Scheperjans, F.

“…Background and purpose The majority of Parkinson's disease (PD) patients suffer from gastrointestinal symptoms of which constipation is considered the most…”
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Analysis of Fungal Flora in Indoor Dust by Ribosomal DNA Sequence Analysis, Quantitative PCR, and Culture by Pitkäranta, M, Meklin, T, Hyvärinen, A, Paulin, L, Auvinen, P, Nevalainen, A, Rintala, H

“…In recent years increasing attention has been given to the potential health effects of fungal exposure in indoor environments. We used large-scale sequencing…”
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Significant disparities in allergy prevalence and microbiota between the young people in Finnish and Russian Karelia by Ruokolainen, L., Paalanen, L., Karkman, A., Laatikainen, T., Hertzen, L., Vlasoff, T., Markelova, O., Masyuk, V., Auvinen, P., Paulin, L., Alenius, H., Fyhrquist, N., Hanski, I., Mäkelä, M. J., Zilber, E., Jousilahti, P., Vartiainen, E., Haahtela, T.

“…Summary Background Atopic allergy has been more common among schoolchildren in Finland, as compared to Russian Karelia. These adjacent regions show one of the…”
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Primary Results on Safety and Efficacy From the LEADLESS II–Phase 2 Worldwide Clinical Trial by Reddy, Vivek Y., Exner, Derek V., Doshi, Rahul, Tomassoni, Gery, Bunch, T. Jared, Estes, N.A. Mark, Neužil, Petr, Paulin, Frédéric L., Garcia Guerrero, Juan Jose, Cantillon, Daniel J.

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Optimizing Lysosomal Activation of Antibody–Drug Conjugates (ADCs) by Incorporation of Novel Cleavable Dipeptide Linkers by Salomon, Paulin L, Reid, Emily E, Archer, Katie E, Harris, Luke, Maloney, Erin K, Wilhelm, Alan J, Miller, Michael L, Chari, Ravi V. J, Keating, Thomas A, Singh, Rajeeva

“…Although peptide linkers are used in multiple clinical-stage ADCs, there are only few reports on optimizing peptide linkers for efficient lysosomal proteolysis…”
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Using amplicon sequencing of rpoB for identification of inoculant rhizobia from peanut nodules by Mousavi, S.A., Gao, Y., Penttinen, P., Frostegård, Å., Paulin, L., Lindström, K.

“…To improve the nitrogen fixation, legume crops are often inoculated with selected effective rhizobia. However, there is large variation in how well the…”
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Mechanisms behind the varying severity of Aleutian mink disease virus: Comparison of three farms with a different disease status by Virtanen, J., Aaltonen, K., Moisander-Jylhä, A.-M., Nordgren, H., Paulin, L., Peura, J., Vapalahti, O., Kant, R., Sironen, T.

“…Aleutian mink disease virus (AMDV) is distributed widely among mink farms and wild mustelids despite ongoing attempts to stop the spread. The severity of…”
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Exercise and arrhythmic risk in TMEM43 p.S358L arrhythmogenic right ventricular cardiomyopathy by Paulin, Frédéric L., Hodgkinson, Kathleen A., MacLaughlan, Sarah, Stuckless, Susan N., Templeton, Christina, Shah, Suryakant, Bremner, Heather, Roberts, Jason D., Young, Terry-Lynn, Parfrey, Patrick S., Connors, Sean P.

“…High-level exercise has been associated with a malignant phenotype in desmosomal and genotype-negative forms of arrhythmogenic right ventricular cardiomyopathy…”
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Comparison of microbial communities in marinated and unmarinated broiler meat by metagenomics by Nieminen, T.T., Koskinen, K., Laine, P., Hultman, J., Säde, E., Paulin, L., Paloranta, A., Johansson, P., Björkroth, J., Auvinen, P.

“…Most raw poultry sold in Finland at the retail level is mixed with marinades containing oil, sugar, spices and acetic acid and packaged under modified…”
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Bidirectional Ventricular Tachycardia in a Postoperative Patient by Duffett, Stephen A., Balan, Marko, Paulin, Frédéric L., Connors, Sean P.

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Reply to Yalta and Yetkin—Cardiac Sarcoidosis: Indications for Implantable Cardioverter-Defibrillator Therapy by Duffett, Stephen A., Paulin, Frédéric L.

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Antibody–Drug Conjugates with Indolinobenzodiazepine Dimer Payloads: DNA-Binding Mechanism of Indolinobenzodiazepine Dimer Catabolites in Target Cancer Cells by Singh, Rajeeva, Reid, Emily E, Harris, Luke, Salomon, Paulin L, Miller, Michael L, Chari, Ravi V. J, Keating, Thomas A

“…DNA-targeting indolinobenzodiazepine dimer (IGN) payloads are used in several clinical-stage antibody–drug conjugates. IGN drugs alkylate DNA through the…”
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Determination of fungal succession during municipal solid waste composting using a cloning-based analysis by Hultman, J, Vasara, T, Partanen, P, Kurola, J, Kontro, M.H, Paulin, L, Auvinen, P, Romantschuk, M

“…The microbiota at industrial full-scale composting plants has earlier been fragmentarily studied with molecular methods. Here, fungal communities from…”
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A systemic disease mimicking a rheumatoid arthritis by Legrand, M, Nouvier, M, Paulin, L, Deschamps, B, Pialat, J B, Coury, F

“…Rare systemic diseases such as amyloidosis can mimic inflammatory rheumatic diseases. Because of their poor prognosis, physicians should rule them out at the…”
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Characterization of psychrotrophic bacterial communities in modified atmosphere-packed meat with terminal restriction fragment length polymorphism by Nieminen, T.T., Vihavainen, E., Paloranta, A., Lehto, J., Paulin, L., Auvinen, P., Solismaa, M., Björkroth, K.J.

“…Characterization of psychrotrophic lactic acid bacteria (LAB) and Brochothrix thermosphacta communities is needed to understand the microbial ecology of…”
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Morphometric Differentiation Among Anastrepha fraterculus (Diptera: Tephritidae) Exploiting Sympatric Alternate Hosts by Gómez-Cendra, P. V, Paulin, L. E, Oroño, L, Ovruski, S. M, Vilardi, J. C

“…Anastrepha fraterculus (Wiedemann) is currently considered a complex of cryptic species infesting fruits from Mexico to Argentina and represents an interesting…”
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Home interventions are effective at decreasing indoor nitrogen dioxide concentrations by Paulin, L. M., Diette, G. B., Scott, M., McCormack, M. C., Matsui, E. C., Curtin-Brosnan, J., Williams, D. L., Kidd-Taylor, A., Shea, M., Breysse, P. N., Hansel, N. N.

“…Nitrogen dioxide (NO2), a by‐product of combustion produced by indoor gas appliances such as cooking stoves, is associated with respiratory symptoms in those…”
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Multiple Intramyocardial Masses in an Otherwise Healthy 35-Year-Old Woman by Powell, Ramsey G.G., Paulin, Frédéric L., Flemming, Jeffrey, Harris, Scott, Duffett, Stephen A.

“…Sarcoidosis with manifest cardiac involvement typically presents with heart failure, conduction abnormalities, or ventricular arrhythmias. Here, we present a…”
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Effects of the use of biocontrol agent (Phlebiopsis gigantea) on fungal communities on the surface of Picea abies stumps by Terhonen, E, Sun, H, Buée, M, Kasanen, R, Paulin, L, Asiegbu, F.O

“…•We used 454-pyrosequencing approach as this has not done before.•We had longer time period (1, 6 and 13years) than previous studies.•Stump treatment should…”
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