Search Results - "Pauli, Chantal"

Suppression of insulin feedback enhances the efficacy of PI3K inhibitors by Hopkins, Benjamin D., Pauli, Chantal, Du, Xing, Wang, Diana G., Li, Xiang, Wu, David, Amadiume, Solomon C., Goncalves, Marcus D., Hodakoski, Cindy, Lundquist, Mark R., Bareja, Rohan, Ma, Yan, Harris, Emily M., Sboner, Andrea, Beltran, Himisha, Rubin, Mark A., Mukherjee, Siddhartha, Cantley, Lewis C.

“…Mutations in PIK3CA , which encodes the p110α subunit of the insulin-activated phosphatidylinositol-3 kinase (PI3K), and loss of function mutations in PTEN ,…”
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High-fructose corn syrup enhances intestinal tumor growth in mice by Goncalves, Marcus D, Lu, Changyuan, Tutnauer, Jordan, Hartman, Travis E, Hwang, Seo-Kyoung, Murphy, Charles J, Pauli, Chantal, Morris, Roxanne, Taylor, Sam, Bosch, Kaitlyn, Yang, Sukjin, Wang, Yumei, Van Riper, Justin, Lekaye, H Carl, Roper, Jatin, Kim, Young, Chen, Qiuying, Gross, Steven S, Rhee, Kyu Y, Cantley, Lewis C, Yun, Jihye

“…Excessive consumption of beverages sweetened with high-fructose corn syrup (HFCS) is associated with obesity and with an increased risk of colorectal cancer…”
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Personalized In Vitro and In Vivo Cancer Models to Guide Precision Medicine by Pauli, Chantal, Hopkins, Benjamin D, Prandi, Davide, Shaw, Reid, Fedrizzi, Tarcisio, Sboner, Andrea, Sailer, Verena, Augello, Michael, Puca, Loredana, Rosati, Rachele, McNary, Terra J, Churakova, Yelena, Cheung, Cynthia, Triscott, Joanna, Pisapia, David, Rao, Rema, Mosquera, Juan Miguel, Robinson, Brian, Faltas, Bishoy M, Emerling, Brooke E, Gadi, Vijayakrishna K, Bernard, Brady, Elemento, Olivier, Beltran, Himisha, Demichelis, Francesca, Kemp, Christopher J, Grandori, Carla, Cantley, Lewis C, Rubin, Mark A

“…Precision medicine is an approach that takes into account the influence of individuals' genes, environment, and lifestyle exposures to tailor interventions…”
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Patient derived organoids to model rare prostate cancer phenotypes by Puca, Loredana, Bareja, Rohan, Prandi, Davide, Shaw, Reid, Benelli, Matteo, Karthaus, Wouter R., Hess, Judy, Sigouros, Michael, Donoghue, Adam, Kossai, Myriam, Gao, Dong, Cyrta, Joanna, Sailer, Verena, Vosoughi, Aram, Pauli, Chantal, Churakova, Yelena, Cheung, Cynthia, Deonarine, Lesa Dayal, McNary, Terra J., Rosati, Rachele, Tagawa, Scott T., Nanus, David M., Mosquera, Juan Miguel, Sawyers, Charles L., Chen, Yu, Inghirami, Giorgio, Rao, Rema A., Grandori, Carla, Elemento, Olivier, Sboner, Andrea, Demichelis, Francesca, Rubin, Mark A., Beltran, Himisha

“…A major hurdle in the study of rare tumors is a lack of existing preclinical models. Neuroendocrine prostate cancer is an uncommon and aggressive histologic…”
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Transplantation of engineered organoids enables rapid generation of metastatic mouse models of colorectal cancer by O'Rourke, Kevin P, Loizou, Evangelia, Livshits, Geulah, Schatoff, Emma M, Baslan, Timour, Manchado, Eusebio, Simon, Janelle, Romesser, Paul B, Leach, Benjamin, Han, Teng, Pauli, Chantal, Beltran, Himisha, Rubin, Mark A, Dow, Lukas E, Lowe, Scott W

“…Genetically engineered colon organoids form tumors that undergo a stepwise progression toward metastatic disease after orthotopic transplantation. Colorectal…”
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Aberrant positivity for BCOR immunohistochemistry in merkel cell carcinoma - a potential diagnostic pitfall by Vetter, Viola Katharina, Haberecker, Martina, Huber, Florian Alexander, Pauli, Chantal

“…Merkel cell carcinoma (MCC) is a rare, aggressive primary cutaneous neuroendocrine carcinoma, frequently associated with clonal Merkel cell polyomavirus…”
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CD8 + T-cells restrict the development of peritoneal metastasis and support the efficacy of hyperthermic intraperitoneal chemotherapy (HIPEC) by Roth, Lilian, Huynh-Russo, Linda, Heeb, Laura, Ulugöl, Sima, Freire Dos Santos, Rafael, Breuer, Eva, Ungethüm, Udo, Haberecker, Martina, Pauli, Chantal, Koelzer, Viktor, Lehmann, Kuno, Gupta, Anurag

“…Multimodal therapy for peritoneal metastasis (PM) including cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) provides…”
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Gout tophus detection—A comparison of dual-energy CT (DECT) and histology by Melzer, Ralph, MD, Pauli, Chantal, MD, Treumann, Thomas, MD, Krauss, Bernhard, PhD

“…Abstract Objectives To compare dual-energy CT images (DECT) directly with gold standard histology. Methods A 85-year-old woman with chronic recurrent gouty…”
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Anterior cruciate ligament changes in the human knee joint in aging and osteoarthritis by Hasegawa, Akihiko, Otsuki, Shuhei, Pauli, Chantal, Miyaki, Shigeru, Patil, Shantanu, Steklov, Nikolai, Kinoshita, Mitsuo, Koziol, James, D'Lima, Darryl D., Lotz, Martin K.

“…Objective The development and patterns of spontaneous age‐related changes in the anterior cruciate ligament (ACL) and their relationship to articular cartilage…”
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CUP-Syndrom – Diagnostik aus Sicht der Pathologie by Pauli Chantal Prof Dr med

“…ZusammenfassungProblemstellungDie histologische und immunhistochemische Aufarbeitung von Tumormaterial aus Metastasen eines bis dahin unbekannten Primärtumors…”
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The long non-coding RNA HOTAIR contributes to joint-specific gene expression in rheumatoid arthritis by Elhai, Muriel, Micheroli, Raphael, Houtman, Miranda, Mirrahimi, Masoumeh, Moser, Larissa, Pauli, Chantal, Bürki, Kristina, Laimbacher, Andrea, Kania, Gabriela, Klein, Kerstin, Schätzle, Philipp, Frank Bertoncelj, Mojca, Edalat, Sam G., Keusch, Leandra, Khmelevskaya, Alexandra, Toitou, Melpomeni, Geiss, Celina, Rauer, Thomas, Sakkou, Maria, Kollias, George, Armaka, Marietta, Distler, Oliver, Ospelt, Caroline

“…Although patients with rheumatoid arthritis (RA) typically exhibit symmetrical joint involvement, some patients develop alternative disease patterns in…”
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A Functional Precision Oncology Approach to Identify Treatment Strategies for Myxofibrosarcoma Patients by Pauli, Chantal, De Boni, Lamberto, Pauwels, Jonathan E, Chen, Yanjiang, Planas-Paz, Lara, Shaw, Reid, Emerling, Brooke M, Grandori, Carla, Hopkins, Benjamin D, Rubin, Mark A

“…In this era of precision medicine, numerous workflows for the targeting of high-recurrent mutations in common tumor types have been developed, leaving patients…”
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Cross-species evaluation of fibroblast activation protein alpha as potential imaging target for soft tissue sarcoma: a comparative immunohistochemical study in humans, dogs, and cats by Beer, Patricia, Pauli, Chantal, Haberecker, Martina, Grest, Paula, Beebe, Erin, Fuchs, Daniel, Markkanen, Enni, Krudewig, Christiane, Nolff, Mirja Christine

“…Introduction Complete surgical tumor resection is paramount in the management of soft tissue sarcoma (STS) in humans, dogs, and cats alike. Near-infrared…”
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Establishment, characterization and functional testing of two novel ex vivo extraskeletal myxoid chondrosarcoma (EMC) cell models by Bangerter, Jana Lucia, Harnisch, Kim Jannis, Chen, Yanjiang, Hagedorn, Catherine, Planas-Paz, Lara, Pauli, Chantal

“…Extraskeletal myxoid chondrosarcoma (EMC) is a malignant mesenchymal neoplasm of uncertain differentiation as classified by the WHO Classification of Tumours…”
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Zone‐specific gene expression patterns in articular cartilage by Grogan, Shawn P., Duffy, Stuart F., Pauli, Chantal, Koziol, James A., Su, Andrew I., D'Lima, Darryl D., Lotz, Martin K.

“…Objective To identify novel genes and pathways specific to the superficial zone (SZ), middle zone (MZ), and deep zone (DZ) of normal articular cartilage…”
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Unravelling homologous recombination repair deficiency and therapeutic opportunities in soft tissue and bone sarcoma by Planas‐Paz, Lara, Pliego‐Mendieta, Alicia, Hagedorn, Catherine, Aguilera‐Garcia, Domingo, Haberecker, Martina, Arnold, Fabian, Herzog, Marius, Bankel, Lorenz, Guggenberger, Roman, Steiner, Sabrina, Chen, Yanjiang, Kahraman, Abdullah, Zoche, Martin, Rubin, Mark A, Moch, Holger, Britschgi, Christian, Pauli, Chantal

“…Defects in homologous recombination repair (HRR) in tumors correlate with poor prognosis and metastases development. Determining HRR deficiency (HRD) is of…”
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Conservative surgical treatment with fertility preservation in a young adult with NTRK rearranged spindle cell neoplasm of the uterine cervix by Bühler, Marco M., Honcharova-Biletska, Hanna, Pauli, Chantal, Chronas, Dimitrios, Bolten, Kristina

“…•NTRK rearranged spindle cell neoplasms of the lower female genital tract are an emerging entity.•Characteristic histomorphological changes can give hints for…”
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S100A1 and S100B Expression Patterns Identify Differentiation Status of Human Articular Chondrocytes by Diaz-Romero, Jose, Quintin, Aurelie, Schoenholzer, Eric, Pauli, Chantal, Despont, Alain, Zumstein, Matthias A., Kohl, Sandro, Nesic, Dobrila

“…Many studies in the field of cell‐based cartilage repair have focused on identifying markers associated with the differentiation status of human articular…”
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Drug screening and genome editing in human pancreatic cancer organoids identifies drug-gene interactions and candidates for off-label therapy by Hirt, Christian K., Booij, Tijmen H., Grob, Linda, Simmler, Patrik, Toussaint, Nora C., Keller, David, Taube, Doreen, Ludwig, Vanessa, Goryachkin, Alexander, Pauli, Chantal, Lenggenhager, Daniela, Stekhoven, Daniel J., Stirnimann, Christian U., Endhardt, Katharina, Ringnalda, Femke, Villiger, Lukas, Siebenhüner, Alexander, Karkampouna, Sofia, De Menna, Marta, Beshay, Janette, Klett, Hagen, Kruithof-de Julio, Marianna, Schüler, Julia, Schwank, Gerald

“…Pancreatic cancer (PDAC) is a highly aggressive malignancy for which the identification of novel therapies is urgently needed. Here, we establish a human PDAC…”
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Cancer Sample Biobanking at the Next Level: Combining Tissue With Living Cell Repositories to Promote Precision Medicine by Bolck, Hella A., Pauli, Chantal, Göbel, Elisabeth, Mühlbauer, Katharina, Dettwiler, Susanne, Moch, Holger, Schraml, Peter

“…Biorespositories of formalin-fixed and paraffin-embedded (FFPE) or fresh frozen human tissues from malignant diseases generated as integral part of the…”
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